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Murcko scaffold

Ring system with 3 rings and 20 atoms

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
31
With full pages
16
Scaffold SMILES

O=C(Nc1ccccn1)c1cc2ccccc2[nH]c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccn1)c1cc2ccccc2[nH]c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

4-Hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1-prop-2-enylquinoline-3-carboxamide chemical structure, C19H17N3O3, CAS 5238-88-0
4-Hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1-prop-2-enylquinoline-3-carboxamide
CAS 5238-88-0C19H17N3O3
N-(5-Chloropyridin-2-yl)-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C17H14ClN3O3, CAS 331829-38-0
N-(5-Chloropyridin-2-yl)-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 331829-38-0C17H14ClN3O3
4-Hydroxy-2-oxo-1-(prop-2-en-1-yl)-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C18H15N3O3, CAS 303798-35-8
4-Hydroxy-2-oxo-1-(prop-2-en-1-yl)-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 303798-35-8C18H15N3O3
1-Hexyl-4-hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C22H25N3O3, CAS 371226-72-1
1-Hexyl-4-hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 371226-72-1C22H25N3O3
N-(5-Chloropyridin-2-yl)-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C16H12ClN3O3, CAS 331829-36-8
N-(5-Chloropyridin-2-yl)-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 331829-36-8C16H12ClN3O3
1-Butyl-4-hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C20H21N3O3, CAS 368434-12-2
1-Butyl-4-hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 368434-12-2C20H21N3O3
4-Hydroxy-2-oxo-1-propyl-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C18H17N3O3, CAS 84088-66-4
4-Hydroxy-2-oxo-1-propyl-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 84088-66-4C18H17N3O3
1-Ethyl-4-hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C18H17N3O3, CAS 330817-79-3
1-Ethyl-4-hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 330817-79-3C18H17N3O3
1-Butyl-4-hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H19N3O4, CAS 300730-79-4
1-Butyl-4-hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 300730-79-4C19H19N3O4
4-Hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C20H21N3O4, CAS 330817-94-2
4-Hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide
CAS 330817-94-2C20H21N3O4
4-Hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H19N3O3, CAS 368432-68-2
4-Hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide
CAS 368432-68-2C19H19N3O3
4-Hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C15H11N3O4, CAS 330817-92-0
4-Hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 330817-92-0C15H11N3O4
4-Hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C18H17N3O4, CAS 304869-53-2
4-Hydroxy-N-(3-hydroxypyridin-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide
CAS 304869-53-2C18H17N3O4
4-Hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H19N3O3, CAS 330817-82-8
4-Hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide
CAS 330817-82-8C19H19N3O3
4-Hydroxy-2-oxo-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C15H11N3O3, CAS 154019-33-7
4-Hydroxy-2-oxo-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 154019-33-7C15H11N3O3
1-Hexyl-4-hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C22H25N3O3, CAS 330817-90-8
1-Hexyl-4-hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 330817-90-8C22H25N3O3
4-Hydroxy-1-methyl-2-oxo-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C16H13N3O3, CAS 84088-58-4
4-Hydroxy-1-methyl-2-oxo-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 84088-58-4C16H13N3O3
1-Ethyl-4-hydroxy-2-oxo-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C17H15N3O3, CAS 154019-34-8
1-Ethyl-4-hydroxy-2-oxo-N-(pyridin-2-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 154019-34-8C17H15N3O3
4-Hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C21H23N3O3, CAS 330817-87-3
4-Hydroxy-N-(4-methylpyridin-2-yl)-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide
CAS 330817-87-3C21H23N3O3
1-Allyl-4-hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H17N3O3, CAS 370873-32-8
1-Allyl-4-hydroxy-N-(6-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 370873-32-8C19H17N3O3
1-Butyl-4-hydroxy-N-(5-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C20H21N3O3, CAS 330817-85-1
1-Butyl-4-hydroxy-N-(5-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 330817-85-1C20H21N3O3
4-Hydroxy-N-(3-methylpyridin-2-yl)-2-oxo-1-(prop-2-en-1-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H17N3O3, CAS 5238-87-9
4-Hydroxy-N-(3-methylpyridin-2-yl)-2-oxo-1-(prop-2-en-1-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 5238-87-9C19H17N3O3
4-Hydroxy-N-(5-methylpyridin-2-yl)-2-oxo-1-(prop-2-en-1-yl)-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H17N3O3, CAS 300838-43-1
4-Hydroxy-N-(5-methylpyridin-2-yl)-2-oxo-1-(prop-2-en-1-yl)-1,2-dihydroquinoline-3-carboxamide
CAS 300838-43-1C19H17N3O3
4-Hydroxy-1-methyl-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C17H15N3O3, CAS 313980-65-3
4-Hydroxy-1-methyl-N-(4-methylpyridin-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 313980-65-3C17H15N3O3