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Murcko scaffold

2-(Thiophen-3-yl)pyrrolidine scaffold

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
22
With full pages
0
Scaffold SMILES

c1cc(C2CCCN2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Thiophen-3-yl)pyrrolidine page
Murcko scaffold c1cc(C2CCCN2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

2-(Thiophen-3-yl)pyrrolidine chemical structure, C8H11NS, CAS 298690-85-4
2-(Thiophen-3-yl)pyrrolidine
CAS 298690-85-4C8H11NS
tert-Butyl 2-(thiophen-3-yl)pyrrolidine-1-carboxylate chemical structure, C13H19NO2S, CAS 1355177-76-2
tert-Butyl 2-(thiophen-3-yl)pyrrolidine-1-carboxylate
CAS 1355177-76-2C13H19NO2S
2-Chloro-1-[2-(thiophen-3-yl)pyrrolidin-1-yl]ethan-1-one chemical structure, C10H12ClNOS, CAS 1179119-21-1
2-Chloro-1-[2-(thiophen-3-yl)pyrrolidin-1-yl]ethan-1-one
CAS 1179119-21-1C10H12ClNOS
1-(2-(Thiophen-3-yl)pyrrolidin-1-yl)ethanone chemical structure, C10H13NOS, CAS 1340217-58-4
1-(2-(Thiophen-3-yl)pyrrolidin-1-yl)ethanone
CAS 1340217-58-4C10H13NOS
1-[2-(Thiophen-3-yl)pyrrolidin-1-yl]prop-2-en-1-one chemical structure, C11H13NOS, CAS 1178943-98-0
1-[2-(Thiophen-3-yl)pyrrolidin-1-yl]prop-2-en-1-one
CAS 1178943-98-0C11H13NOS
1-Ethyl-2-(thiophen-3-yl)pyrrolidin-3-amine chemical structure, C10H16N2S, CAS 1339084-05-7
1-Ethyl-2-(thiophen-3-yl)pyrrolidin-3-amine
CAS 1339084-05-7C10H16N2S
1-Methyl-2-(thiophen-3-yl)pyrrolidin-3-amine chemical structure, C9H14N2S, CAS 1341995-65-0
1-Methyl-2-(thiophen-3-yl)pyrrolidin-3-amine
CAS 1341995-65-0C9H14N2S
2,2-Dimethyl-1-[2-(thiophen-3-yl)pyrrolidin-1-yl]propan-1-one chemical structure, C13H19NOS, CAS 1498742-53-2
2,2-Dimethyl-1-[2-(thiophen-3-yl)pyrrolidin-1-yl]propan-1-one
CAS 1498742-53-2C13H19NOS
2-(Thiophen-3-yl)pyrrolidine-1-carbaldehyde chemical structure, C9H11NOS, CAS 1355233-92-9
2-(Thiophen-3-yl)pyrrolidine-1-carbaldehyde
CAS 1355233-92-9C9H11NOS
2-(2,5-Dimethylthiophen-3-yl)pyrrolidine chemical structure, C10H15NS, CAS 1337290-61-5
2-(2,5-Dimethylthiophen-3-yl)pyrrolidine
CAS 1337290-61-5C10H15NS
2-(4-Methylthiophen-3-yl)pyrrolidine chemical structure, C9H13NS, CAS 1535323-63-7
2-(4-Methylthiophen-3-yl)pyrrolidine
CAS 1535323-63-7C9H13NS
2-(5-Bromothiophen-3-yl)pyrrolidine chemical structure, C8H10BrNS, CAS 1513033-11-8
2-(5-Bromothiophen-3-yl)pyrrolidine
CAS 1513033-11-8C8H10BrNS
2-(5-Chlorothiophen-3-yl)pyrrolidine chemical structure, C8H10ClNS, CAS 1514853-19-0
2-(5-Chlorothiophen-3-yl)pyrrolidine
CAS 1514853-19-0C8H10ClNS
1-Butyl-2-(thiophen-3-yl)pyrrolidine chemical structure, C12H19NS, CAS 1355182-41-0
1-Butyl-2-(thiophen-3-yl)pyrrolidine
CAS 1355182-41-0C12H19NS
1-Methyl-5-(thiophen-3-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H13NO2S, CAS 2098126-71-5
1-Methyl-5-(thiophen-3-yl)pyrrolidine-3-carboxylic acid
CAS 2098126-71-5C10H13NO2S
(1-Methyl-5-(thiophen-3-yl)pyrrolidin-3-yl)methanol chemical structure, C10H15NOS, CAS 2098037-92-2
(1-Methyl-5-(thiophen-3-yl)pyrrolidin-3-yl)methanol
CAS 2098037-92-2C10H15NOS
Methyl 3-(pyrrolidin-2-yl)thiophene-2-carboxylate chemical structure, C10H13NO2S, CAS 1824444-08-7
Methyl 3-(pyrrolidin-2-yl)thiophene-2-carboxylate
CAS 1824444-08-7C10H13NO2S
2-(5-Bromothiophen-3-yl)pyrrolidine hydrochloride chemical structure, C8H11BrClNS, CAS 2742660-96-2
2-(5-Bromothiophen-3-yl)pyrrolidine hydrochloride
CAS 2742660-96-2C8H11BrClNS
rac-(2R,3S)-1-(Propan-2-yl)-2-(thiophen-3-yl)pyrrolidin-3-amine chemical structure, C11H18N2S, CAS 2227689-26-9
rac-(2R,3S)-1-(Propan-2-yl)-2-(thiophen-3-yl)pyrrolidin-3-amine
CAS 2227689-26-9C11H18N2S
rac-(2R,3S)-1-Propyl-2-[5-(trifluoromethyl)thiophen-3-yl]pyrrolidin-3-amine chemical structure, C12H17F3N2S, CAS 2227647-26-7
rac-(2R,3S)-1-Propyl-2-[5-(trifluoromethyl)thiophen-3-yl]pyrrolidin-3-amine
CAS 2227647-26-7C12H17F3N2S
rac-(2R,3S)-1-(Propan-2-yl)-2-[5-(trifluoromethyl)thiophen-3-yl]pyrrolidin-3-amine chemical structure, C12H17F3N2S, CAS 2227897-35-8
rac-(2R,3S)-1-(Propan-2-yl)-2-[5-(trifluoromethyl)thiophen-3-yl]pyrrolidin-3-amine
CAS 2227897-35-8C12H17F3N2S
rac-(2R,3S)-1-Propyl-2-(thiophen-3-yl)pyrrolidin-3-amine chemical structure, C11H18N2S, CAS 2227846-46-8
rac-(2R,3S)-1-Propyl-2-(thiophen-3-yl)pyrrolidin-3-amine
CAS 2227846-46-8C11H18N2S