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Murcko scaffold

Ring system with 2 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
10
With full pages
5
Scaffold SMILES

O=C(NNC(=O)c1ccc[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NNC(=O)c1ccc[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Ethyl 2,4-dimethyl-5-[[(3-methylbenzoyl)amino]carbamoyl]-1H-pyrrole-3-carboxylate chemical structure, C18H21N3O4, CAS 865615-23-2
Ethyl 2,4-dimethyl-5-[[(3-methylbenzoyl)amino]carbamoyl]-1H-pyrrole-3-carboxylate
CAS 865615-23-2C18H21N3O4
Ethyl 5-(benzamidocarbamoyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate chemical structure, C17H19N3O4, CAS 825599-53-9
Ethyl 5-(benzamidocarbamoyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS 825599-53-9C17H19N3O4
4-Acetyl-N'-(5-chloro-2-methoxybenzoyl)-3,5-dimethyl-1H-pyrrole-2-carbohydrazide chemical structure, C17H18ClN3O4, CAS 784160-42-5
4-Acetyl-N'-(5-chloro-2-methoxybenzoyl)-3,5-dimethyl-1H-pyrrole-2-carbohydrazide
CAS 784160-42-5C17H18ClN3O4
Ethyl 5-[[(3-bromobenzoyl)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate chemical structure, C17H18BrN3O4, CAS 865615-21-0
Ethyl 5-[[(3-bromobenzoyl)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS 865615-21-0C17H18BrN3O4
Ethyl 5-[[(4-bromobenzoyl)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate chemical structure, C17H18BrN3O4, CAS 849478-35-9
Ethyl 5-[[(4-bromobenzoyl)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS 849478-35-9C17H18BrN3O4
Ethyl 5-[[(4-chlorobenzoyl)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate chemical structure, C17H18ClN3O4, CAS 850090-27-6
Ethyl 5-[[(4-chlorobenzoyl)amino]carbamoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS 850090-27-6C17H18ClN3O4
4-Acetyl-N'-(4-bromobenzoyl)-3,5-dimethyl-1H-pyrrole-2-carbohydrazide chemical structure, C16H16BrN3O3, CAS 794538-13-9
4-Acetyl-N'-(4-bromobenzoyl)-3,5-dimethyl-1H-pyrrole-2-carbohydrazide
CAS 794538-13-9C16H16BrN3O3
1H-Pyrrole-2-carboxylic acid, 2-[3-(trifluoromethyl)benzoyl]hydrazide chemical structure, C13H10F3N3O2, CAS 259792-95-5
1H-Pyrrole-2-carboxylic acid, 2-[3-(trifluoromethyl)benzoyl]hydrazide
CAS 259792-95-5C13H10F3N3O2
N'-(4-Methoxybenzoyl)-1H-pyrrole-2-carbohydrazide chemical structure, C13H13N3O3, CAS 1111575-81-5
N'-(4-Methoxybenzoyl)-1H-pyrrole-2-carbohydrazide
CAS 1111575-81-5C13H13N3O3
4-Bromo-N'-(3-methoxy-4-methylbenzoyl)-1-methyl-1H-pyrrole-2-carbohydrazide chemical structure, C15H16BrN3O3, CAS 1010411-23-0
4-Bromo-N'-(3-methoxy-4-methylbenzoyl)-1-methyl-1H-pyrrole-2-carbohydrazide
CAS 1010411-23-0C15H16BrN3O3