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Murcko scaffold

1-{[4-(Benzyloxy)phenyl]methyl}piperazine scaffold

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
12
With full pages
3
Scaffold SMILES

c1ccc(COc2ccc(CN3CCNCC3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-{[4-(Benzyloxy)phenyl]methyl}piperazine page
Murcko scaffold c1ccc(COc2ccc(CN3CCNCC3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1-[4-(Benzyloxy)-3-methoxybenzyl]-4-(propylsulfonyl)piperazine chemical structure, C22H30N2O4S, CAS 439939-60-3
1-[4-(Benzyloxy)-3-methoxybenzyl]-4-(propylsulfonyl)piperazine
CAS 439939-60-3C22H30N2O4S
1-[4-(Benzyloxy)benzyl]-4-methylpiperazine chemical structure, C19H24N2O, CAS 415929-58-7
1-[4-(Benzyloxy)benzyl]-4-methylpiperazine
CAS 415929-58-7C19H24N2O
1-[4-(Benzyloxy)-3-methoxybenzyl]-4-ethylpiperazine chemical structure, C21H28N2O2, CAS 415932-58-0
1-[4-(Benzyloxy)-3-methoxybenzyl]-4-ethylpiperazine
CAS 415932-58-0C21H28N2O2
1-[4-(Benzyloxy)-3-methoxybenzyl]-4-(methylsulfonyl)piperazine chemical structure, C20H26N2O4S, CAS 429624-21-5
1-[4-(Benzyloxy)-3-methoxybenzyl]-4-(methylsulfonyl)piperazine
CAS 429624-21-5C20H26N2O4S
1-{[4-(Benzyloxy)phenyl]methyl}piperazine chemical structure, C18H22N2O, CAS 523980-10-1
1-{[4-(Benzyloxy)phenyl]methyl}piperazine
CAS 523980-10-1C18H22N2O
1-[4-(Benzyloxy)-3-methoxybenzyl]piperazine chemical structure, C19H24N2O2, CAS 523980-01-0
1-[4-(Benzyloxy)-3-methoxybenzyl]piperazine
CAS 523980-01-0C19H24N2O2
1-{[4-(Benzyloxy)phenyl]methyl}-4-(3-methoxypropyl)piperazine chemical structure, C22H30N2O2, CAS 918480-12-3
1-{[4-(Benzyloxy)phenyl]methyl}-4-(3-methoxypropyl)piperazine
CAS 918480-12-3C22H30N2O2
1-{[4-(Benzyloxy)phenyl]methyl}piperazine dihydrochloride chemical structure, C18H24Cl2N2O, CAS 2059948-03-5
1-{[4-(Benzyloxy)phenyl]methyl}piperazine dihydrochloride
CAS 2059948-03-5C18H24Cl2N2O
2-(Benzyloxy)-5-((4-(2,2,2-trifluoroethyl)piperazin-1-yl)methyl)benzoic acid dihydrochloride chemical structure, C21H25Cl2F3N2O3, CAS 3078475-82-5
2-(Benzyloxy)-5-((4-(2,2,2-trifluoroethyl)piperazin-1-yl)methyl)benzoic acid dihydrochloride
CAS 3078475-82-5C21H25Cl2F3N2O3
2-(Benzyloxy)-5-((4-isopropylpiperazin-1-yl)methyl)benzoic acid dihydrochloride chemical structure, C22H30Cl2N2O3, CAS 3078562-98-5
2-(Benzyloxy)-5-((4-isopropylpiperazin-1-yl)methyl)benzoic acid dihydrochloride
CAS 3078562-98-5C22H30Cl2N2O3
2-(Benzyloxy)-5-((4-ethylpiperazin-1-yl)methyl)benzoic acid dihydrochloride chemical structure, C21H28Cl2N2O3, CAS 3078561-05-1
2-(Benzyloxy)-5-((4-ethylpiperazin-1-yl)methyl)benzoic acid dihydrochloride
CAS 3078561-05-1C21H28Cl2N2O3
2-(Benzyloxy)-5-((4-methylpiperazin-1-yl)methyl)benzoic acid dihydrochloride chemical structure, C20H26Cl2N2O3, CAS 3078567-93-5
2-(Benzyloxy)-5-((4-methylpiperazin-1-yl)methyl)benzoic acid dihydrochloride
CAS 3078567-93-5C20H26Cl2N2O3