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Murcko scaffold

Ring system with 3 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
7
With full pages
2
Scaffold SMILES

c1ccc(-c2ncnc(Nc3ccncc3)n2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ncnc(Nc3ccncc3)n2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

6-(6-(Trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazine-2,4-diamine chemical structure, C15H9F6N7, CAS 1643852-84-9
6-(6-(Trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazine-2,4-diamine
CAS 1643852-84-9C15H9F6N7
Enasidenib chemical structure, C19H17F6N7O, CAS 1446502-11-9
Enasidenib
CAS 1446502-11-9C19H17F6N7O
1-[(4-{[2-(1,1-Difluoroethyl)pyridin-4-yl]amino}-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl)amino]-2-methylpropan-2-ol chemical structure, C20H20F5N7O, CAS 1446505-52-7
1-[(4-{[2-(1,1-Difluoroethyl)pyridin-4-yl]amino}-6-[6-(trifluoromethyl)pyridin-2-yl]-1,3,5-triazin-2-yl)amino]-2-methylpropan-2-ol
CAS 1446505-52-7C20H20F5N7O
2-N-Propan-2-yl-4-N-[2-(trifluoromethyl)-4-pyridinyl]-6-[6-(trifluoromethyl)-2-pyridinyl]-1,3,5-triazine-2,4-diamine chemical structure, C18H15F6N7, CAS 1446501-77-4
2-N-Propan-2-yl-4-N-[2-(trifluoromethyl)-4-pyridinyl]-6-[6-(trifluoromethyl)-2-pyridinyl]-1,3,5-triazine-2,4-diamine
CAS 1446501-77-4C18H15F6N7
4-Chloro-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine chemical structure, C15H7ClF6N6, CAS 1446507-68-1
4-Chloro-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine
CAS 1446507-68-1C15H7ClF6N6
Enasidenib mesylate chemical structure, C20H21F6N7O4S, CAS 1650550-25-6
Enasidenib mesylate
CAS 1650550-25-6C20H21F6N7O4S
2-N-[(2-Methylpropan-2-yl)oxy]-4-N-[2-(trifluoromethyl)-4-pyridinyl]-6-[6-(trifluoromethyl)-2-pyridinyl]-1,3,5-triazine-2,4-diamine chemical structure, C19H17F6N7O, CAS 2071196-10-4
2-N-[(2-Methylpropan-2-yl)oxy]-4-N-[2-(trifluoromethyl)-4-pyridinyl]-6-[6-(trifluoromethyl)-2-pyridinyl]-1,3,5-triazine-2,4-diamine
CAS 2071196-10-4C19H17F6N7O