CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
7
With full pages
2
Scaffold SMILES

c1ccc(-c2ccnc(Nc3ccccn3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc(Nc3ccccn3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone chemical structure, C19H18F2N4O2S, CAS 1610358-53-6
((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone
CAS 1610358-53-6C19H18F2N4O2S
(S)-((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone hydrochloride chemical structure, C19H19ClF2N4O2S, CAS 1610368-60-9
(S)-((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone hydrochloride
CAS 1610368-60-9C19H19ClF2N4O2S
5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(methylsulfanyl)methyl]pyridin-2-yl}pyridin-2-amine chemical structure, C19H17F2N3OS, CAS 1602486-04-3
5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(methylsulfanyl)methyl]pyridin-2-yl}pyridin-2-amine
CAS 1602486-04-3C19H17F2N3OS
(2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methanol chemical structure, C18H15F2N3O2, CAS 1602486-05-4
(2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methanol
CAS 1602486-05-4C18H15F2N3O2
Enitociclib chemical structure, C19H18F2N4O2S, CAS 1610408-97-3
Enitociclib
CAS 1610408-97-3C19H18F2N4O2S
(S)-((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone hydrochloride chemical structure, C19H19ClF2N4O2S
(S)-((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone hydrochloride
C19H19ClF2N4O2S
(R)-((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone hydrochloride chemical structure, C19H19ClF2N4O2S, CAS 1610368-59-6
(R)-((2-((5-Fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)pyridin-4-yl)methyl)(imino)(methyl)-l6-sulfanone hydrochloride
CAS 1610368-59-6C19H19ClF2N4O2S