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Murcko scaffold

1,2,3,4-Tetrahydro-1,8-naphthyridine scaffold

257 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
257
With full pages
38
Scaffold SMILES

c1cnc2c(c1)CCCN2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydro-1,8-naphthyridine page
Murcko scaffold c1cnc2c(c1)CCCN2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 257 chemicals

tert-Butyl 7-(4-hydroxybutyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C17H26N2O3, CAS 2376266-04-3
tert-Butyl 7-(4-hydroxybutyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 2376266-04-3C17H26N2O3
N-(2-Methoxyethyl)-4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanamide chemical structure, C15H23N3O2, CAS 2376265-90-4
N-(2-Methoxyethyl)-4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanamide
CAS 2376265-90-4C15H23N3O2
N-(2-Methoxyethyl)-4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-butanamine chemical structure, C15H25N3O, CAS 2376265-88-0
N-(2-Methoxyethyl)-4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-butanamine
CAS 2376265-88-0C15H25N3O
Methyl (S)-2-Amino-4-[(2-methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]butanoate chemical structure, C20H34N4O3, CAS 2376266-05-4
Methyl (S)-2-Amino-4-[(2-methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]butanoate
CAS 2376266-05-4C20H34N4O3
Methyl (S)-2-((tert-butoxycarbonyl)amino)-4-((2-methoxyethyl)(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl)amino)butanoate chemical structure, C25H42N4O5, CAS 2376266-16-7
Methyl (S)-2-((tert-butoxycarbonyl)amino)-4-((2-methoxyethyl)(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl)amino)butanoate
CAS 2376266-16-7C25H42N4O5
Methyl 2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylate chemical structure, C11H14N2O2, CAS 2411288-03-2
Methyl 2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylate
CAS 2411288-03-2C11H14N2O2
Methyl 3-(2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanoate hydrochloride chemical structure, C13H19ClN2O2, CAS 2411271-87-7
Methyl 3-(2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanoate hydrochloride
CAS 2411271-87-7C13H19ClN2O2
Methyl 3-(2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanoate chemical structure, C13H18N2O2, CAS 2411269-55-9
Methyl 3-(2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanoate
CAS 2411269-55-9C13H18N2O2
5,6,7,8-Tetrahydro-1,8-naphthyridine-3-carboxylic acid hydrochloride chemical structure, C9H11ClN2O2, CAS 2411263-64-2
5,6,7,8-Tetrahydro-1,8-naphthyridine-3-carboxylic acid hydrochloride
CAS 2411263-64-2C9H11ClN2O2
2-Methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid hydrochloride chemical structure, C10H13ClN2O2, CAS 2408975-33-5
2-Methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid hydrochloride
CAS 2408975-33-5C10H13ClN2O2
2-Methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid chemical structure, C10H12N2O2, CAS 2408971-18-4
2-Methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid
CAS 2408971-18-4C10H12N2O2
Methyl 7,7-dimethyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylate chemical structure, C12H16N2O2, CAS 2412577-43-4
Methyl 7,7-dimethyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylate
CAS 2412577-43-4C12H16N2O2
Methyl 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoate chemical structure, C13H18N2O2, CAS 2639420-21-4
Methyl 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoate
CAS 2639420-21-4C13H18N2O2
3,3-Dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C10H14N2, CAS 2445786-89-8
3,3-Dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 2445786-89-8C10H14N2
5-(8-Boc-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoic Acid chemical structure, C18H26N2O4, CAS 2206777-48-0
5-(8-Boc-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoic Acid
CAS 2206777-48-0C18H26N2O4
8-[(tert-Butoxy)carbonyl]-2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid chemical structure, C15H20N2O4, CAS 2445785-70-4
8-[(tert-Butoxy)carbonyl]-2-methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carboxylic acid
CAS 2445785-70-4C15H20N2O4
6-Bromo-3,3-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine hydrobromide chemical structure, C10H14Br2N2, CAS 2624139-11-1
6-Bromo-3,3-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine hydrobromide
CAS 2624139-11-1C10H14Br2N2
5-Bromo-1-methyl-3,4-dihydro-2H-1,8-naphthyridine chemical structure, C9H11BrN2, CAS 2628351-63-1
5-Bromo-1-methyl-3,4-dihydro-2H-1,8-naphthyridine
CAS 2628351-63-1C9H11BrN2
1,2,3,4-Tetrahydro-1,8-naphthyridin-3-amine chemical structure, C8H11N3, CAS 2749733-49-9
1,2,3,4-Tetrahydro-1,8-naphthyridin-3-amine
CAS 2749733-49-9C8H11N3
5,6,7,8-Tetrahydro-1,8-naphthyridine-2-carbaldehyde hydrochloride chemical structure, C9H11ClN2O, CAS 2803476-82-4
5,6,7,8-Tetrahydro-1,8-naphthyridine-2-carbaldehyde hydrochloride
CAS 2803476-82-4C9H11ClN2O
6-Bromo-3-ethyl-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C10H13BrN2, CAS 2749733-45-5
6-Bromo-3-ethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 2749733-45-5C10H13BrN2
4-Methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-2-carboxylic acid chemical structure, C10H12N2O2, CAS 2137763-00-7
4-Methyl-5,6,7,8-tetrahydro-1,8-naphthyridine-2-carboxylic acid
CAS 2137763-00-7C10H12N2O2
tert-Butyl 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carboxylate chemical structure, C13H18N2O2, CAS 2169355-96-6
tert-Butyl 5,6,7,8-tetrahydro-1,8-naphthyridine-2-carboxylate
CAS 2169355-96-6C13H18N2O2
7-Chloro-1,2,3,4-tetrahydro-1,8-naphthyridine hydrochloride chemical structure, C8H10Cl2N2, CAS 2792186-73-1
7-Chloro-1,2,3,4-tetrahydro-1,8-naphthyridine hydrochloride
CAS 2792186-73-1C8H10Cl2N2