CompoundList
Sign in
Murcko scaffold

1,2,3,4-Tetrahydro-1,8-naphthyridine scaffold

257 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
257
With full pages
38
Scaffold SMILES

c1cnc2c(c1)CCCN2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydro-1,8-naphthyridine page
Murcko scaffold c1cnc2c(c1)CCCN2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 257 chemicals

1,8-Naphthyridine, 1,2,3,4-tetrahydro-5-(2-(dimethylamino)ethoxy)-1-methyl- chemical structure, C13H21N3O, CAS 102280-57-9
1,8-Naphthyridine, 1,2,3,4-tetrahydro-5-(2-(dimethylamino)ethoxy)-1-methyl-
CAS 102280-57-9C13H21N3O
3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-amine chemical structure, C11H17N3, CAS 206989-41-5
3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-amine
CAS 206989-41-5C11H17N3
3-(5-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-pentanoylamino)-propionic acid chemical structure, C16H23N3O3, CAS 227751-90-8
3-(5-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-pentanoylamino)-propionic acid
CAS 227751-90-8C16H23N3O3
tert-Butyl 7-chloro-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C13H17ClN2O2, CAS 679392-23-5
tert-Butyl 7-chloro-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 679392-23-5C13H17ClN2O2
1-(7-Methyl-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)ethanone chemical structure, C11H14N2O, CAS 226711-03-1
1-(7-Methyl-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)ethanone
CAS 226711-03-1C11H14N2O
1,8-Naphthyridin-3-ol, 5,6,7,8-tetrahydro-2,4,8-trimethyl- chemical structure, C11H16N2O, CAS 627098-03-7
1,8-Naphthyridin-3-ol, 5,6,7,8-tetrahydro-2,4,8-trimethyl-
CAS 627098-03-7C11H16N2O
2-(3-(Boc-amino)-propyl)-5,6,7,8-tetrahydro-1,8-naphthyridine chemical structure, C16H25N3O2, CAS 227751-86-2
2-(3-(Boc-amino)-propyl)-5,6,7,8-tetrahydro-1,8-naphthyridine
CAS 227751-86-2C16H25N3O2
6-Bromo-5,7-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C10H13BrN2, CAS 698974-42-4
6-Bromo-5,7-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 698974-42-4C10H13BrN2
Methyl 5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoate chemical structure, C14H20N2O2, CAS 227751-47-5
Methyl 5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoate
CAS 227751-47-5C14H20N2O2
7-(2-Hydroxyethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C10H14N2O, CAS 243641-39-6
7-(2-Hydroxyethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 243641-39-6C10H14N2O
tert-Butyl 3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C13H18N2O2, CAS 335030-36-9
tert-Butyl 3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 335030-36-9C13H18N2O2
tert-Butyl 6-bromo-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C13H17BrN2O2, CAS 335030-38-1
tert-Butyl 6-bromo-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 335030-38-1C13H17BrN2O2
N-Methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carbothioamide chemical structure, C10H13N3S, CAS 60782-40-3
N-Methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carbothioamide
CAS 60782-40-3C10H13N3S
5,7-Dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C10H14N2, CAS 65541-95-9
5,7-Dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 65541-95-9C10H14N2
1,2,3,4-Tetrahydro-1,8-naphthyridine chemical structure, C8H10N2, CAS 13623-87-5
1,2,3,4-Tetrahydro-1,8-naphthyridine
CAS 13623-87-5C8H10N2
4-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)butanoic acid chemical structure, C12H16N2O2, CAS 332884-21-6
4-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)butanoic acid
CAS 332884-21-6C12H16N2O2
tert-Butyl 7-formyl-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxylate chemical structure, C14H18N2O3, CAS 912270-39-4
tert-Butyl 7-formyl-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxylate
CAS 912270-39-4C14H18N2O3
tert-Butyl 7-ethenyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxylate chemical structure, C15H20N2O2, CAS 912270-30-5
tert-Butyl 7-ethenyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxylate
CAS 912270-30-5C15H20N2O2
tert-Butyl 7-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C14H20N2O2, CAS 243641-37-4
tert-Butyl 7-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 243641-37-4C14H20N2O2
7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C11H16N2O2, CAS 204452-91-5
7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 204452-91-5C11H16N2O2
6-Bromo-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C8H9BrN2, CAS 1023813-80-0
6-Bromo-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 1023813-80-0C8H9BrN2
(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)methanamine chemical structure, C9H13N3, CAS 332883-10-0
(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)methanamine
CAS 332883-10-0C9H13N3
7-Ethyl-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C10H14N2, CAS 1785021-80-8
7-Ethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 1785021-80-8C10H14N2
tert-Butyl (4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl)carbamate chemical structure, C17H27N3O2, CAS 380396-36-1
tert-Butyl (4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl)carbamate
CAS 380396-36-1C17H27N3O2