CompoundList
Sign in
Murcko scaffold

1,2,3,4-Tetrahydro-1,8-naphthyridine scaffold

257 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
257
With full pages
38
Scaffold SMILES

c1cnc2c(c1)CCCN2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydro-1,8-naphthyridine page
Murcko scaffold c1cnc2c(c1)CCCN2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 257 chemicals

3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-ol chemical structure, C11H16N2O, CAS 669076-64-6
3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-ol
CAS 669076-64-6C11H16N2O
1,2,3,4-Tetrahydro-1,8-naphthyridin-4-amine chemical structure, C8H11N3, CAS 2580211-18-1
1,2,3,4-Tetrahydro-1,8-naphthyridin-4-amine
CAS 2580211-18-1C8H11N3
4-(Iodoethynyl)-1,5,6,7-tetrahydro-1,8-naphthyridine chemical structure, C10H9IN2, CAS 1174297-61-0
4-(Iodoethynyl)-1,5,6,7-tetrahydro-1,8-naphthyridine
CAS 1174297-61-0C10H9IN2
1,2,3,4-Tetrahydro-[1,8]naphthyridine-2-carboxylic acid chemical structure, C9H10N2O2, CAS 1245913-51-2
1,2,3,4-Tetrahydro-[1,8]naphthyridine-2-carboxylic acid
CAS 1245913-51-2C9H10N2O2
2,3,4,8-Tetrahydro-1,8-naphthyridine-4-carboxylic acid chemical structure, C9H10N2O2, CAS 2345601-38-7
2,3,4,8-Tetrahydro-1,8-naphthyridine-4-carboxylic acid
CAS 2345601-38-7C9H10N2O2
tert-Butyl 7-(1-hydroxypropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C16H24N2O3, CAS 959992-13-3
tert-Butyl 7-(1-hydroxypropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 959992-13-3C16H24N2O3
tert-Butyl 5,7-dimethyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxylate chemical structure, C15H22N2O2, CAS 721921-53-5
tert-Butyl 5,7-dimethyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxylate
CAS 721921-53-5C15H22N2O2
5-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)pentanoic acid hydrochloride chemical structure, C13H19ClN2O2, CAS 227751-48-6
5-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)pentanoic acid hydrochloride
CAS 227751-48-6C13H19ClN2O2
5,6,7,8-Tetrahydro-1,8-naphthyridin-2-butyric acid hydrochloride chemical structure, C12H17ClN2O2, CAS 193818-31-4
5,6,7,8-Tetrahydro-1,8-naphthyridin-2-butyric acid hydrochloride
CAS 193818-31-4C12H17ClN2O2
5,6,7,8-Tetrahydro-1,8-naphthyridin-2-amine chemical structure, C8H11N3, CAS 2375262-20-5
5,6,7,8-Tetrahydro-1,8-naphthyridin-2-amine
CAS 2375262-20-5C8H11N3
tert-Butyl 7-(3-ethoxy-3-oxopropyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C18H26N2O4, CAS 1272758-04-9
tert-Butyl 7-(3-ethoxy-3-oxopropyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1272758-04-9C18H26N2O4
tert-Butyl N-[3-(1,2,3,4-tetrahydro-1,8-naphthyridin-2-yl)propyl]carbamate chemical structure, C16H25N3O2, CAS 678987-75-2
tert-Butyl N-[3-(1,2,3,4-tetrahydro-1,8-naphthyridin-2-yl)propyl]carbamate
CAS 678987-75-2C16H25N3O2
5-Ethoxy-1,7-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine chemical structure, C12H18N2O, CAS 62481-29-2
5-Ethoxy-1,7-dimethyl-1,2,3,4-tetrahydro-1,8-naphthyridine
CAS 62481-29-2C12H18N2O
tert-Butyl 7-(1-methoxy-1-oxopropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C17H24N2O4, CAS 1416440-33-9
tert-Butyl 7-(1-methoxy-1-oxopropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1416440-33-9C17H24N2O4
tert-Butyl 7-(2-cyanoethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C16H21N3O2, CAS 1416438-77-1
tert-Butyl 7-(2-cyanoethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1416438-77-1C16H21N3O2
tert-Butyl 7-(3-hydroxypropyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C16H24N2O3, CAS 1416438-76-0
tert-Butyl 7-(3-hydroxypropyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1416438-76-0C16H24N2O3
tert-Butyl 7-(3-oxopropyl)-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxylate chemical structure, C16H22N2O3, CAS 755042-83-2
tert-Butyl 7-(3-oxopropyl)-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxylate
CAS 755042-83-2C16H22N2O3
tert-Butyl 7-(2-methoxy-2-oxoethyl)-4-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C17H24N2O4, CAS 1416440-55-5
tert-Butyl 7-(2-methoxy-2-oxoethyl)-4-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1416440-55-5C17H24N2O4
Methyl 2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoate hydrochloride chemical structure, C12H17ClN2O2, CAS 1416439-20-7
Methyl 2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoate hydrochloride
CAS 1416439-20-7C12H17ClN2O2
2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-ol hydrochloride chemical structure, C11H17ClN2O, CAS 1416438-68-0
2-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-ol hydrochloride
CAS 1416438-68-0C11H17ClN2O
tert-Butyl 7-(1-aminopropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C16H25N3O2, CAS 1416439-47-8
tert-Butyl 7-(1-aminopropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1416439-47-8C16H25N3O2
tert-Butyl 7-(1-methoxy-2-methyl-1-oxopropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate chemical structure, C18H26N2O4, CAS 1416438-93-1
tert-Butyl 7-(1-methoxy-2-methyl-1-oxopropan-2-yl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate
CAS 1416438-93-1C18H26N2O4
Methyl 2-methyl-2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoate hydrochloride chemical structure, C13H19ClN2O2, CAS 1416439-53-6
Methyl 2-methyl-2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoate hydrochloride
CAS 1416439-53-6C13H19ClN2O2
2-Methyl-2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propan-1-ol hydrochloride chemical structure, C12H19ClN2O, CAS 1416438-91-9
2-Methyl-2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propan-1-ol hydrochloride
CAS 1416438-91-9C12H19ClN2O