CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
10
With full pages
0
Scaffold SMILES

O=C(CCCc1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCCc1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Chlorambucyl-proline chemical structure, C19H26Cl2N2O3, CAS 81050-71-7
Chlorambucyl-proline
CAS 81050-71-7C19H26Cl2N2O3
L-Proline, 1-(1-oxo-4-phenylbutyl)- chemical structure, C15H19NO3, CAS 86778-86-1
L-Proline, 1-(1-oxo-4-phenylbutyl)-
CAS 86778-86-1C15H19NO3
1-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-proline chemical structure, C15H20N2O4, CAS 62023-67-0
1-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-proline
CAS 62023-67-0C15H20N2O4
4-(4-Methoxyphenyl)-1-[2-(2,2,2-trifluoro-1-hydroxyethyl)-1-pyrrolidinyl]-1-butanone chemical structure, C17H22F3NO3, CAS 119004-27-2
4-(4-Methoxyphenyl)-1-[2-(2,2,2-trifluoro-1-hydroxyethyl)-1-pyrrolidinyl]-1-butanone
CAS 119004-27-2C17H22F3NO3
1-(3-Aminopyrrolidin-1-yl)-4-phenylbutan-1-one chemical structure, C14H20N2O, CAS 1272181-79-9
1-(3-Aminopyrrolidin-1-yl)-4-phenylbutan-1-one
CAS 1272181-79-9C14H20N2O
1-(3-Hydroxypyrrolidin-1-yl)-4-phenylbutan-1-one chemical structure, C14H19NO2, CAS 1273964-31-0
1-(3-Hydroxypyrrolidin-1-yl)-4-phenylbutan-1-one
CAS 1273964-31-0C14H19NO2
4-(4-Chlorophenyl)-4-hydroxy-1-(pyrrolidin-1-yl)butan-1-one chemical structure, C14H18ClNO2, CAS 64081-73-8
4-(4-Chlorophenyl)-4-hydroxy-1-(pyrrolidin-1-yl)butan-1-one
CAS 64081-73-8C14H18ClNO2
4-(4-Bromophenyl)-1-(1-pyrrolidinyl)-1-butanone chemical structure, C14H18BrNO, CAS 13734-68-4
4-(4-Bromophenyl)-1-(1-pyrrolidinyl)-1-butanone
CAS 13734-68-4C14H18BrNO
1-(2-Cyano-4-phenylbutanoyl)-4,4-difluoropyrrolidine-2-carbonitrile chemical structure, C16H15F2N3O, CAS 2392934-90-4
1-(2-Cyano-4-phenylbutanoyl)-4,4-difluoropyrrolidine-2-carbonitrile
CAS 2392934-90-4C16H15F2N3O
4-(4-Chlorophenyl)-1-(3-methoxypyrrolidin-1-yl)butan-1-one chemical structure, C15H20ClNO2, CAS 2344597-85-7
4-(4-Chlorophenyl)-1-(3-methoxypyrrolidin-1-yl)butan-1-one
CAS 2344597-85-7C15H20ClNO2