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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,249 to 1,296 of 1,868 chemicals

tert-Butyl N-[(2R)-1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate chemical structure, C11H16N2O3S, CAS 2137093-51-5
tert-Butyl N-[(2R)-1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate
CAS 2137093-51-5C11H16N2O3S
tert-Butyl N-[(2R)-1-oxo-1-(1,2-thiazol-5-yl)propan-2-yl]carbamate chemical structure, C11H16N2O3S, CAS 2137034-27-4
tert-Butyl N-[(2R)-1-oxo-1-(1,2-thiazol-5-yl)propan-2-yl]carbamate
CAS 2137034-27-4C11H16N2O3S
tert-Butyl N-[(2S)-1-oxo-1-(1,2-thiazol-3-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2137035-80-2
tert-Butyl N-[(2S)-1-oxo-1-(1,2-thiazol-3-yl)butan-2-yl]carbamate
CAS 2137035-80-2C12H18N2O3S
tert-Butyl N-[(2S)-1-oxo-1-(1,2-thiazol-4-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2137035-96-0
tert-Butyl N-[(2S)-1-oxo-1-(1,2-thiazol-4-yl)butan-2-yl]carbamate
CAS 2137035-96-0C12H18N2O3S
tert-Butyl N-[(2S)-1-(3-methyl-1,2-thiazol-5-yl)-1-oxopropan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2137136-02-6
tert-Butyl N-[(2S)-1-(3-methyl-1,2-thiazol-5-yl)-1-oxopropan-2-yl]carbamate
CAS 2137136-02-6C12H18N2O3S
tert-Butyl N-[(2S)-1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate chemical structure, C11H16N2O3S, CAS 2137136-05-9
tert-Butyl N-[(2S)-1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate
CAS 2137136-05-9C11H16N2O3S
tert-Butyl N-[1-(3-methyl-1,2-thiazol-5-yl)-1-oxopropan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2028852-34-6
tert-Butyl N-[1-(3-methyl-1,2-thiazol-5-yl)-1-oxopropan-2-yl]carbamate
CAS 2028852-34-6C12H18N2O3S
tert-Butyl N-[4-oxo-4-(1,2-thiazol-5-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2005503-46-6
tert-Butyl N-[4-oxo-4-(1,2-thiazol-5-yl)butan-2-yl]carbamate
CAS 2005503-46-6C12H18N2O3S
tert-Butyl N-[2-(3-methyl-1,2-thiazol-5-yl)-2-oxoethyl]carbamate chemical structure, C11H16N2O3S, CAS 2020894-66-8
tert-Butyl N-[2-(3-methyl-1,2-thiazol-5-yl)-2-oxoethyl]carbamate
CAS 2020894-66-8C11H16N2O3S
tert-Butyl N-methyl-N-[(2S)-1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2136091-15-9
tert-Butyl N-methyl-N-[(2S)-1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate
CAS 2136091-15-9C12H18N2O3S
tert-Butyl N-[2-methyl-3-oxo-3-(1,2-thiazol-4-yl)propyl]carbamate chemical structure, C12H18N2O3S, CAS 2017048-08-5
tert-Butyl N-[2-methyl-3-oxo-3-(1,2-thiazol-4-yl)propyl]carbamate
CAS 2017048-08-5C12H18N2O3S
tert-Butyl N-methyl-N-[2-oxo-2-(1,2-thiazol-3-yl)ethyl]carbamate chemical structure, C11H16N2O3S, CAS 2008742-28-5
tert-Butyl N-methyl-N-[2-oxo-2-(1,2-thiazol-3-yl)ethyl]carbamate
CAS 2008742-28-5C11H16N2O3S
1-Amino-3-(1,2-thiazol-5-yl)propan-2-one chemical structure, C6H8N2OS, CAS 2026363-29-9
1-Amino-3-(1,2-thiazol-5-yl)propan-2-one
CAS 2026363-29-9C6H8N2OS
tert-Butyl N-[3-oxo-4-(1,2-thiazol-5-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2011038-43-8
tert-Butyl N-[3-oxo-4-(1,2-thiazol-5-yl)butan-2-yl]carbamate
CAS 2011038-43-8C12H18N2O3S
4-(2-Bromoethenyl)-3-methoxy-1,2-thiazole chemical structure, C6H6BrNOS, CAS 2138805-22-6
4-(2-Bromoethenyl)-3-methoxy-1,2-thiazole
CAS 2138805-22-6C6H6BrNOS
Ethyl 3-(1,2-thiazol-4-yl)prop-2-ynoate chemical structure, C8H7NO2S, CAS 2008506-52-1
Ethyl 3-(1,2-thiazol-4-yl)prop-2-ynoate
CAS 2008506-52-1C8H7NO2S
tert-Butyl 3-(1,2-thiazol-3-yl)prop-2-ynoate chemical structure, C10H11NO2S, CAS 2137830-81-8
tert-Butyl 3-(1,2-thiazol-3-yl)prop-2-ynoate
CAS 2137830-81-8C10H11NO2S
tert-Butyl N-[4-oxo-4-(1,2-thiazol-3-yl)butyl]carbamate chemical structure, C12H18N2O3S, CAS 1996449-81-0
tert-Butyl N-[4-oxo-4-(1,2-thiazol-3-yl)butyl]carbamate
CAS 1996449-81-0C12H18N2O3S
2,2-Difluoro-3-(3-methoxy-1,2-thiazol-4-yl)propanoic acid chemical structure, C7H7F2NO3S, CAS 2137916-50-6
2,2-Difluoro-3-(3-methoxy-1,2-thiazol-4-yl)propanoic acid
CAS 2137916-50-6C7H7F2NO3S
2,2-Difluoro-3-(3-methoxy-1,2-thiazol-5-yl)propanoic acid chemical structure, C7H7F2NO3S, CAS 2138337-06-9
2,2-Difluoro-3-(3-methoxy-1,2-thiazol-5-yl)propanoic acid
CAS 2138337-06-9C7H7F2NO3S
2,2-Difluoro-3-{[(1,2-thiazol-4-yl)methyl]amino}propanoic acid chemical structure, C7H8F2N2O2S, CAS 2137572-39-3
2,2-Difluoro-3-{[(1,2-thiazol-4-yl)methyl]amino}propanoic acid
CAS 2137572-39-3C7H8F2N2O2S
(3-Amino-2,2-difluoropropyl)(methyl)[(1,2-thiazol-3-yl)methyl]amine chemical structure, C8H13F2N3S, CAS 2138427-78-6
(3-Amino-2,2-difluoropropyl)(methyl)[(1,2-thiazol-3-yl)methyl]amine
CAS 2138427-78-6C8H13F2N3S
(3-Amino-2,2-difluoropropyl)(methyl)[(1,2-thiazol-5-yl)methyl]amine chemical structure, C8H13F2N3S, CAS 2018154-64-6
(3-Amino-2,2-difluoropropyl)(methyl)[(1,2-thiazol-5-yl)methyl]amine
CAS 2018154-64-6C8H13F2N3S
tert-Butyl N-[1-oxo-1-(1,2-thiazol-4-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2023438-36-8
tert-Butyl N-[1-oxo-1-(1,2-thiazol-4-yl)butan-2-yl]carbamate
CAS 2023438-36-8C12H18N2O3S