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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings: 1
Scaffold atoms: 5
Chemicals: 1,868
With full pages: 279

Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold Open the Isothiazole page

Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,489 to 1,536 of 1,868 chemicals

4-{[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl]amino}pentan-1-ol chemical structure, C11H20N2O2S, CAS 2138067-29-3

4-{[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl]amino}pentan-1-ol

CAS 2138067-29-3C₁₁H₂₀N₂O₂S

1-(3-Methoxy-1,2-thiazol-4-yl)pent-4-en-1-one chemical structure, C9H11NO2S, CAS 2172056-70-9

1-(3-Methoxy-1,2-thiazol-4-yl)pent-4-en-1-one

CAS 2172056-70-9C₉H₁₁NO₂S

(2R)-2-Amino-3-(3-methoxy-1,2-thiazol-5-yl)propanoic acid chemical structure, C7H10N2O3S, CAS 1998629-13-2

(2R)-2-Amino-3-(3-methoxy-1,2-thiazol-5-yl)propanoic acid

CAS 1998629-13-2C₇H₁₀N₂O₃S

(3R)-3-Amino-3-(3-methoxy-1,2-thiazol-4-yl)propanamide chemical structure, C7H11N3O2S, CAS 2136079-18-8

(3R)-3-Amino-3-(3-methoxy-1,2-thiazol-4-yl)propanamide

CAS 2136079-18-8C₇H₁₁N₃O₂S

2,2-Difluoro-3-hydroxy-3-(1,2-thiazol-4-yl)propanoic acid chemical structure, C6H5F2NO3S, CAS 2172473-52-6

2,2-Difluoro-3-hydroxy-3-(1,2-thiazol-4-yl)propanoic acid

CAS 2172473-52-6C₆H₅F₂NO₃S

4-(1,2-Thiazol-5-yl)butan-1-ol chemical structure, C7H11NOS, CAS 2010598-12-4

4-(1,2-Thiazol-5-yl)butan-1-ol

CAS 2010598-12-4C₇H₁₁NOS

3-Bromo-1,2-thiazole-4-carbaldehyde chemical structure, C4H2BrNOS, CAS 2248299-10-5

3-Bromo-1,2-thiazole-4-carbaldehyde

CAS 2248299-10-5C₄H₂BrNOS

Methyl 5-amino-1,2-thiazole-3-carboxylate hydrochloride chemical structure, C5H7ClN2O2S, CAS 2460756-44-7

Methyl 5-amino-1,2-thiazole-3-carboxylate hydrochloride

CAS 2460756-44-7C₅H₇ClN₂O₂S

N-(3-Amino-4-methylpentyl)-3,4-dichloro-N-methyl-1,2-thiazole-5-carboxamide hydrochloride chemical structure, C11H18Cl3N3OS, CAS 2743438-36-8

N-(3-Amino-4-methylpentyl)-3,4-dichloro-N-methyl-1,2-thiazole-5-carboxamide hydrochloride

CAS 2743438-36-8C₁₁H₁₈Cl₃N₃OS

tert-Butyl N-[(2R)-4-oxo-4-(1,2-thiazol-3-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2136030-05-0

tert-Butyl N-[(2R)-4-oxo-4-(1,2-thiazol-3-yl)butan-2-yl]carbamate

CAS 2136030-05-0C₁₂H₁₈N₂O₃S

(3R)-3-Amino-1-(1,2-thiazol-5-yl)butan-1-one chemical structure, C7H10N2OS, CAS 2136241-45-5

(3R)-3-Amino-1-(1,2-thiazol-5-yl)butan-1-one

CAS 2136241-45-5C₇H₁₀N₂OS

2-Amino-1-(1,2-thiazol-4-yl)butan-1-one chemical structure, C7H10N2OS, CAS 2013019-63-9

2-Amino-1-(1,2-thiazol-4-yl)butan-1-one

CAS 2013019-63-9C₇H₁₀N₂OS

5-(3-Bromo-2,2-dimethylpropyl)-1,2-thiazole chemical structure, C8H12BrNS, CAS 2013373-76-5

5-(3-Bromo-2,2-dimethylpropyl)-1,2-thiazole

CAS 2013373-76-5C₈H₁₂BrNS

5-(4-Bromo-3,3-dimethylbutyl)-1,2-thiazole chemical structure, C9H14BrNS, CAS 2137702-19-1

5-(4-Bromo-3,3-dimethylbutyl)-1,2-thiazole

CAS 2137702-19-1C₉H₁₄BrNS

[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl](pentan-3-yl)amine chemical structure, C11H20N2OS, CAS 2138567-04-9

[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl](pentan-3-yl)amine

CAS 2138567-04-9C₁₁H₂₀N₂OS

2-{[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl]amino}acetonitrile chemical structure, C8H11N3OS, CAS 2138054-49-4

2-{[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl]amino}acetonitrile

CAS 2138054-49-4C₈H₁₁N₃OS

4-{[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl]amino}butan-2-ol chemical structure, C10H18N2O2S, CAS 2138054-51-8

4-{[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl]amino}butan-2-ol

CAS 2138054-51-8C₁₀H₁₈N₂O₂S

[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl](3-methoxy-2-methylpropyl)amine chemical structure, C11H20N2O2S, CAS 2138545-37-4

[1-(3-Methoxy-1,2-thiazol-5-yl)ethyl](3-methoxy-2-methylpropyl)amine

CAS 2138545-37-4C₁₁H₂₀N₂O₂S

(But-3-yn-2-yl)[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]amine chemical structure, C10H14N2OS, CAS 2138089-79-7

(But-3-yn-2-yl)[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]amine

CAS 2138089-79-7C₁₀H₁₄N₂OS

2,2-Difluoro-2-(3-methoxy-1,2-thiazol-4-yl)acetic acid chemical structure, C6H5F2NO3S, CAS 2138528-82-0

2,2-Difluoro-2-(3-methoxy-1,2-thiazol-4-yl)acetic acid

CAS 2138528-82-0C₆H₅F₂NO₃S

5-(2-Bromoethenyl)-3-methoxy-1,2-thiazole chemical structure, C6H6BrNOS, CAS 2138816-58-5

5-(2-Bromoethenyl)-3-methoxy-1,2-thiazole

CAS 2138816-58-5C₆H₆BrNOS

Methyl 3-(1,2-thiazol-4-yl)prop-2-ynoate chemical structure, C7H5NO2S, CAS 2010108-13-9

Methyl 3-(1,2-thiazol-4-yl)prop-2-ynoate

CAS 2010108-13-9C₇H₅NO₂S

tert-Butyl N-[1-oxo-1-(1,2-thiazol-5-yl)butan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2024860-76-0

tert-Butyl N-[1-oxo-1-(1,2-thiazol-5-yl)butan-2-yl]carbamate

CAS 2024860-76-0C₁₂H₁₈N₂O₃S

4-(Bromomethyl)-3,5-dimethoxy-1,2-thiazole chemical structure, C6H8BrNO2S, CAS 2138261-74-0

4-(Bromomethyl)-3,5-dimethoxy-1,2-thiazole

CAS 2138261-74-0C₆H₈BrNO₂S