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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,585 to 1,632 of 1,868 chemicals

3-(4-Bromo-1,2-thiazol-3-yl)propanoic acid chemical structure, C6H6BrNO2S, CAS 1710-81-2
3-(4-Bromo-1,2-thiazol-3-yl)propanoic acid
CAS 1710-81-2C6H6BrNO2S
4-(Methylsulfanyl)-1,2-thiazole-3-carboxylic acid chemical structure, C5H5NO2S2, CAS 2829321-25-5
4-(Methylsulfanyl)-1,2-thiazole-3-carboxylic acid
CAS 2829321-25-5C5H5NO2S2
3-(5-Formyl-1,2-thiazol-4-yl)prop-2-ynoic acid chemical structure, C7H3NO3S, CAS 2169592-59-8
3-(5-Formyl-1,2-thiazol-4-yl)prop-2-ynoic acid
CAS 2169592-59-8C7H3NO3S
3-Chloro-5-(ethylsulfanyl)-1,2-thiazole-4-carbonitrile chemical structure, C6H5ClN2S2, CAS 89581-73-7
3-Chloro-5-(ethylsulfanyl)-1,2-thiazole-4-carbonitrile
CAS 89581-73-7C6H5ClN2S2
4-Methanesulfonyl-1,2-thiazole-3-carboxylic acid chemical structure, C5H5NO4S2, CAS 2870701-86-1
4-Methanesulfonyl-1,2-thiazole-3-carboxylic acid
CAS 2870701-86-1C5H5NO4S2
2-{[4-Cyano-5-(ethylsulfanyl)-1,2-thiazol-3-yl]sulfanyl}acetic acid chemical structure, C8H8N2O2S3, CAS 2825011-80-9
2-{[4-Cyano-5-(ethylsulfanyl)-1,2-thiazol-3-yl]sulfanyl}acetic acid
CAS 2825011-80-9C8H8N2O2S3
2-{[4-Cyano-5-(ethylsulfanyl)-1,2-thiazol-3-yl]oxy}acetic acid chemical structure, C8H8N2O3S2, CAS 2825011-28-5
2-{[4-Cyano-5-(ethylsulfanyl)-1,2-thiazol-3-yl]oxy}acetic acid
CAS 2825011-28-5C8H8N2O3S2
2-(4-Bromo-1,2-thiazol-5-yl)-2-fluoroacetic acid chemical structure, C5H3BrFNO2S, CAS 2138044-52-5
2-(4-Bromo-1,2-thiazol-5-yl)-2-fluoroacetic acid
CAS 2138044-52-5C5H3BrFNO2S
4-(1-Ethoxyethenyl)-1,2-thiazole-3-carboxylic acid chemical structure, C8H9NO3S, CAS 2138237-40-6
4-(1-Ethoxyethenyl)-1,2-thiazole-3-carboxylic acid
CAS 2138237-40-6C8H9NO3S
(2E)-2-[(1,2-Thiazol-4-yl)methylidene]butanoic acid chemical structure, C8H9NO2S, CAS 2138805-54-4
(2E)-2-[(1,2-Thiazol-4-yl)methylidene]butanoic acid
CAS 2138805-54-4C8H9NO2S
2,2-Difluoro-3-(1,2-thiazol-3-yl)propanoic acid chemical structure, C6H5F2NO2S, CAS 2137981-99-6
2,2-Difluoro-3-(1,2-thiazol-3-yl)propanoic acid
CAS 2137981-99-6C6H5F2NO2S
2-(4-Chloro-3-methoxy-1,2-thiazol-5-yl)acetic acid chemical structure, C6H6ClNO3S, CAS 2138568-22-4
2-(4-Chloro-3-methoxy-1,2-thiazol-5-yl)acetic acid
CAS 2138568-22-4C6H6ClNO3S
2-(1,2-Thiazol-4-yl)butanoic acid chemical structure, C7H9NO2S, CAS 1539071-64-1
2-(1,2-Thiazol-4-yl)butanoic acid
CAS 1539071-64-1C7H9NO2S
2-(3-Methoxy-1,2-thiazol-4-yl)propanoic acid chemical structure, C7H9NO3S, CAS 2138072-63-4
2-(3-Methoxy-1,2-thiazol-4-yl)propanoic acid
CAS 2138072-63-4C7H9NO3S
2-(3-Methoxy-1,2-thiazol-4-yl)acetic acid chemical structure, C6H7NO3S, CAS 2138106-63-3
2-(3-Methoxy-1,2-thiazol-4-yl)acetic acid
CAS 2138106-63-3C6H7NO3S
2-Hydroxy-3-(3-methoxy-1,2-thiazol-4-yl)propanoic acid chemical structure, C7H9NO4S, CAS 2172052-29-6
2-Hydroxy-3-(3-methoxy-1,2-thiazol-4-yl)propanoic acid
CAS 2172052-29-6C7H9NO4S
2,2-Difluoro-3-(1,2-thiazol-4-yl)propanoic acid chemical structure, C6H5F2NO2S, CAS 2137983-75-4
2,2-Difluoro-3-(1,2-thiazol-4-yl)propanoic acid
CAS 2137983-75-4C6H5F2NO2S
3-Hydroxy-3-(1,2-thiazol-4-yl)propanoic acid chemical structure, C6H7NO3S, CAS 2147890-85-3
3-Hydroxy-3-(1,2-thiazol-4-yl)propanoic acid
CAS 2147890-85-3C6H7NO3S
3-(3-Methylisothiazol-5-yl)acrylic acid chemical structure, C7H7NO2S, CAS 1577-64-6
3-(3-Methylisothiazol-5-yl)acrylic acid
CAS 1577-64-6C7H7NO2S
tert-Butyl N-methyl-N-[2-oxo-2-(1,2-thiazol-5-yl)ethyl]carbamate chemical structure, C11H16N2O3S, CAS 2018751-82-9
tert-Butyl N-methyl-N-[2-oxo-2-(1,2-thiazol-5-yl)ethyl]carbamate
CAS 2018751-82-9C11H16N2O3S
1-(3-Methoxy-1,2-thiazol-4-yl)-4-methylpentan-1-one chemical structure, C10H15NO2S, CAS 2172476-20-7
1-(3-Methoxy-1,2-thiazol-4-yl)-4-methylpentan-1-one
CAS 2172476-20-7C10H15NO2S
(2S)-2-(Methylamino)-1-(1,2-thiazol-4-yl)propan-1-one chemical structure, C7H10N2OS, CAS 2107806-64-2
(2S)-2-(Methylamino)-1-(1,2-thiazol-4-yl)propan-1-one
CAS 2107806-64-2C7H10N2OS
1-(3-Methoxy-1,2-thiazol-4-yl)butan-1-one chemical structure, C8H11NO2S, CAS 2152358-32-0
1-(3-Methoxy-1,2-thiazol-4-yl)butan-1-one
CAS 2152358-32-0C8H11NO2S
tert-Butyl N-methyl-N-[3-oxo-3-(1,2-thiazol-4-yl)propyl]carbamate chemical structure, C12H18N2O3S, CAS 2020133-41-7
tert-Butyl N-methyl-N-[3-oxo-3-(1,2-thiazol-4-yl)propyl]carbamate
CAS 2020133-41-7C12H18N2O3S