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Murcko scaffold

6-Phenyl-2-pyridone scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
360
With full pages
43
Scaffold SMILES

O=c1cccc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-2-pyridone page
Murcko scaffold O=c1cccc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 360 of 360 chemicals

6-(4-Fluoro-2-methoxyphenyl)-2(1H)-pyridinone chemical structure, C12H10FNO2, CAS 1111111-12-6
6-(4-Fluoro-2-methoxyphenyl)-2(1H)-pyridinone
CAS 1111111-12-6C12H10FNO2
6-(2-Chloro-5-methylphenyl)-2(1H)-pyridinone chemical structure, C12H10ClNO, CAS 1111111-25-1
6-(2-Chloro-5-methylphenyl)-2(1H)-pyridinone
CAS 1111111-25-1C12H10ClNO
6-(2-Acetylphenyl)-2(1H)-pyridinone chemical structure, C13H11NO2, CAS 1111111-60-4
6-(2-Acetylphenyl)-2(1H)-pyridinone
CAS 1111111-60-4C13H11NO2
6-(5-Chloro-2-fluorophenyl)-2(1H)-pyridinone chemical structure, C11H7ClFNO, CAS 1111114-18-1
6-(5-Chloro-2-fluorophenyl)-2(1H)-pyridinone
CAS 1111114-18-1C11H7ClFNO
tert-Butyl {[4-(6-oxo-1,6-dihydropyridin-2-yl)phenyl]methyl}carbamate chemical structure, C17H20N2O3, CAS 1111114-53-4
tert-Butyl {[4-(6-oxo-1,6-dihydropyridin-2-yl)phenyl]methyl}carbamate
CAS 1111114-53-4C17H20N2O3
6-[4-(Bromomethyl)phenyl]-2(1H)-pyridinone chemical structure, C12H10BrNO, CAS 1111114-76-1
6-[4-(Bromomethyl)phenyl]-2(1H)-pyridinone
CAS 1111114-76-1C12H10BrNO
2-(1,6-Dihydro-6-oxo-2-pyridinyl)benzoic acid chemical structure, C12H9NO3, CAS 1111110-81-6
2-(1,6-Dihydro-6-oxo-2-pyridinyl)benzoic acid
CAS 1111110-81-6C12H9NO3
N-[2-(1,6-Dihydro-6-oxo-2-pyridinyl)phenyl]acetamide chemical structure, C13H12N2O2, CAS 1111110-96-3
N-[2-(1,6-Dihydro-6-oxo-2-pyridinyl)phenyl]acetamide
CAS 1111110-96-3C13H12N2O2
6-(4-Fluoro-3-nitrophenyl)pyridin-2-ol chemical structure, C11H7FN2O3, CAS 1111111-77-3
6-(4-Fluoro-3-nitrophenyl)pyridin-2-ol
CAS 1111111-77-3C11H7FN2O3
4-Chloro-6-(2-chlorophenyl)-2(1H)-pyridinone chemical structure, C11H7Cl2NO, CAS 2125950-07-2
4-Chloro-6-(2-chlorophenyl)-2(1H)-pyridinone
CAS 2125950-07-2C11H7Cl2NO
3-Chloro-6-phenylpyridin-2(1H)-one chemical structure, C11H8ClNO, CAS 1805642-81-2
3-Chloro-6-phenylpyridin-2(1H)-one
CAS 1805642-81-2C11H8ClNO
4-Fluoro-6-phenylpyridin-2(1H)-one chemical structure, C11H8FNO, CAS 1806294-79-0
4-Fluoro-6-phenylpyridin-2(1H)-one
CAS 1806294-79-0C11H8FNO
Methyl 6-(3-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate chemical structure, C13H10ClNO3, CAS 2120828-58-0
Methyl 6-(3-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate
CAS 2120828-58-0C13H10ClNO3
3-(1-Aminopropylidene)-1-methyl-6-phenylpyridine-2,4(1H,3H)-dione chemical structure, C15H16N2O2, CAS 62613-70-1
3-(1-Aminopropylidene)-1-methyl-6-phenylpyridine-2,4(1H,3H)-dione
CAS 62613-70-1C15H16N2O2
4-Hydroxy-6-[2-(trifluoromethyl)phenyl]pyridin-2(1H)-one chemical structure, C12H8F3NO2, CAS 2287228-38-8
4-Hydroxy-6-[2-(trifluoromethyl)phenyl]pyridin-2(1H)-one
CAS 2287228-38-8C12H8F3NO2
6-(3-(Hydroxymethyl)phenyl)pyridin-2-ol hydrochloride chemical structure, C12H12ClNO2, CAS 2260937-91-3
6-(3-(Hydroxymethyl)phenyl)pyridin-2-ol hydrochloride
CAS 2260937-91-3C12H12ClNO2
3,5-Dichloro-6-phenylpyridin-2(1H)-one chemical structure, C11H7Cl2NO, CAS 5186-16-3
3,5-Dichloro-6-phenylpyridin-2(1H)-one
CAS 5186-16-3C11H7Cl2NO
3-Bromo-6-phenylpyridin-2(1H)-one chemical structure, C11H8BrNO, CAS 2168372-44-7
3-Bromo-6-phenylpyridin-2(1H)-one
CAS 2168372-44-7C11H8BrNO
4-Amino-6-(2-fluoro-6-methoxyphenyl)-1-isopropyl-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C16H18FN3O3, CAS 2872869-41-3
4-Amino-6-(2-fluoro-6-methoxyphenyl)-1-isopropyl-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 2872869-41-3C16H18FN3O3
6-(4-Amino-3-fluorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11FN2O, CAS 2866425-74-1
6-(4-Amino-3-fluorophenyl)-1-methylpyridin-2(1H)-one
CAS 2866425-74-1C12H11FN2O
6-(4-Amino-3-fluorophenyl)pyridin-2-ol chemical structure, C11H9FN2O, CAS 2639539-40-3
6-(4-Amino-3-fluorophenyl)pyridin-2-ol
CAS 2639539-40-3C11H9FN2O
3-(Aminomethyl)-6-phenyl-4-(trifluoromethyl)-2(1H)-pyridinone chemical structure, C13H11F3N2O, CAS 771583-29-0
3-(Aminomethyl)-6-phenyl-4-(trifluoromethyl)-2(1H)-pyridinone
CAS 771583-29-0C13H11F3N2O
4-(1,2-Dihydro-2-oxo-6-phenylpyridin-3-yl)-2-methyl-2-(methylsulfonyl)butanoic acid chemical structure, C17H19NO5S, CAS 1358778-30-9
4-(1,2-Dihydro-2-oxo-6-phenylpyridin-3-yl)-2-methyl-2-(methylsulfonyl)butanoic acid
CAS 1358778-30-9C17H19NO5S
3-(Aminomethyl)-6-phenyl-1,2-dihydropyridin-2-one hydrochloride chemical structure, C12H13ClN2O, CAS 3026728-79-7
3-(Aminomethyl)-6-phenyl-1,2-dihydropyridin-2-one hydrochloride
CAS 3026728-79-7C12H13ClN2O