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Murcko scaffold

6-Phenyl-2-pyridone scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
360
With full pages
43
Scaffold SMILES

O=c1cccc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-2-pyridone page
Murcko scaffold O=c1cccc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 360 chemicals

6-(2-Fluoro-3-trifluoromethylphenyl)-2-hydroxypyridine chemical structure, C12H7F4NO, CAS 1261940-08-2
6-(2-Fluoro-3-trifluoromethylphenyl)-2-hydroxypyridine
CAS 1261940-08-2C12H7F4NO
6-(4-Fluoro-3-trifluoromethylphenyl)-2-hydroxypyridine chemical structure, C12H7F4NO, CAS 1261896-26-7
6-(4-Fluoro-3-trifluoromethylphenyl)-2-hydroxypyridine
CAS 1261896-26-7C12H7F4NO
6-(3,5-Dicarboxyphenyl)-2-hydroxypyridine chemical structure, C13H9NO5, CAS 1261997-77-6
6-(3,5-Dicarboxyphenyl)-2-hydroxypyridine
CAS 1261997-77-6C13H9NO5
6-[4-(Ethylcarbamoyl)-3-fluorophenyl]-2-hydroxypyridine chemical structure, C14H13FN2O2, CAS 1261893-05-3
6-[4-(Ethylcarbamoyl)-3-fluorophenyl]-2-hydroxypyridine
CAS 1261893-05-3C14H13FN2O2
6-[4-(Ethoxycarbonyl)-3-fluorophenyl]-2-hydroxypyridine chemical structure, C14H12FNO3, CAS 1111105-44-2
6-[4-(Ethoxycarbonyl)-3-fluorophenyl]-2-hydroxypyridine
CAS 1111105-44-2C14H12FNO3
6-(2-Chloro-5-methoxycarbonylphenyl)-2-hydroxypyridine chemical structure, C13H10ClNO3, CAS 1261975-52-3
6-(2-Chloro-5-methoxycarbonylphenyl)-2-hydroxypyridine
CAS 1261975-52-3C13H10ClNO3
6-(3-Chloro-4-methoxycarbonylphenyl)-2-hydroxypyridine chemical structure, C13H10ClNO3, CAS 1261889-32-0
6-(3-Chloro-4-methoxycarbonylphenyl)-2-hydroxypyridine
CAS 1261889-32-0C13H10ClNO3
6-(4-Chloro-3-methoxycarbonylphenyl)-2-hydroxypyridine chemical structure, C13H10ClNO3, CAS 1261997-86-7
6-(4-Chloro-3-methoxycarbonylphenyl)-2-hydroxypyridine
CAS 1261997-86-7C13H10ClNO3
2-Hydroxy-6-(3-methylsulfonylaminophenyl)pyridine chemical structure, C12H12N2O3S, CAS 1261909-93-6
2-Hydroxy-6-(3-methylsulfonylaminophenyl)pyridine
CAS 1261909-93-6C12H12N2O3S
2-Hydroxy-6-(2-methoxy-5-trifluoromethylphenyl)pyridine chemical structure, C13H10F3NO2, CAS 1261910-22-8
2-Hydroxy-6-(2-methoxy-5-trifluoromethylphenyl)pyridine
CAS 1261910-22-8C13H10F3NO2
2-Hydroxy-6-(4-methoxy-3-trifluoromethylphenyl)pyridine chemical structure, C13H10F3NO2, CAS 1261973-77-6
2-Hydroxy-6-(4-methoxy-3-trifluoromethylphenyl)pyridine
CAS 1261973-77-6C13H10F3NO2
6-(2-N,N-Dimethylsulfamoylphenyl)-2-hydroxypyridine chemical structure, C13H14N2O3S, CAS 1261940-49-1
6-(2-N,N-Dimethylsulfamoylphenyl)-2-hydroxypyridine
CAS 1261940-49-1C13H14N2O3S
6-(3-N,N-Dimethylsulfamoylphenyl)-2-hydroxypyridine chemical structure, C13H14N2O3S, CAS 1261974-13-3
6-(3-N,N-Dimethylsulfamoylphenyl)-2-hydroxypyridine
CAS 1261974-13-3C13H14N2O3S
6-(4-N,N-Dimethylsulfamoylphenyl)-2-hydroxypyridine chemical structure, C13H14N2O3S, CAS 1261910-38-6
6-(4-N,N-Dimethylsulfamoylphenyl)-2-hydroxypyridine
CAS 1261910-38-6C13H14N2O3S
6-(3-Boc-aminophenyl)-2-hydroxypyridine chemical structure, C16H18N2O3, CAS 1261993-40-1
6-(3-Boc-aminophenyl)-2-hydroxypyridine
CAS 1261993-40-1C16H18N2O3
6-(4-Boc-aminophenyl)-2-hydroxypyridine chemical structure, C16H18N2O3, CAS 1111114-28-3
6-(4-Boc-aminophenyl)-2-hydroxypyridine
CAS 1111114-28-3C16H18N2O3
6-(3-T-Butylsulfamoylphenyl)-2-hydroxypyridine chemical structure, C15H18N2O3S, CAS 1261940-68-4
6-(3-T-Butylsulfamoylphenyl)-2-hydroxypyridine
CAS 1261940-68-4C15H18N2O3S
6-(4-T-Butylsulfamoylphenyl)-2-hydroxypyridine chemical structure, C15H18N2O3S, CAS 1261940-78-6
6-(4-T-Butylsulfamoylphenyl)-2-hydroxypyridine
CAS 1261940-78-6C15H18N2O3S
6-(3-Fluorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile chemical structure, C13H6F4N2O, CAS 1271477-23-6
6-(3-Fluorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile
CAS 1271477-23-6C13H6F4N2O
4-(Trifluoromethyl)-6-(4-trifluoromethylphenyl)-1,2-dihydro-2-oxopyridine-3-carbonitrile chemical structure, C14H6F6N2O, CAS 951231-23-5
4-(Trifluoromethyl)-6-(4-trifluoromethylphenyl)-1,2-dihydro-2-oxopyridine-3-carbonitrile
CAS 951231-23-5C14H6F6N2O
6-(3,4-Dichlorophenyl)-3-hydroxy-1-methylpyridin-2-one chemical structure, C12H9Cl2NO2, CAS 1333146-43-2
6-(3,4-Dichlorophenyl)-3-hydroxy-1-methylpyridin-2-one
CAS 1333146-43-2C12H9Cl2NO2
6-(4-Chlorophenyl)-3-hydroxy-1-methylpyridin-2(1H)-one chemical structure, C12H10ClNO2, CAS 1333146-82-9
6-(4-Chlorophenyl)-3-hydroxy-1-methylpyridin-2(1H)-one
CAS 1333146-82-9C12H10ClNO2
6-(3-Bromophenyl)pyridin-2(1H)-one chemical structure, C11H8BrNO, CAS 149557-05-1
6-(3-Bromophenyl)pyridin-2(1H)-one
CAS 149557-05-1C11H8BrNO
6-(3,5-Dipropoxyphenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile chemical structure, C18H20N2O3, CAS 142499-57-8
6-(3,5-Dipropoxyphenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile
CAS 142499-57-8C18H20N2O3