CompoundList
Sign in
Murcko scaffold

6-Phenyl-2-pyridone scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
360
With full pages
43
Scaffold SMILES

O=c1cccc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-2-pyridone page
Murcko scaffold O=c1cccc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 289 to 336 of 360 chemicals

6-(4-Bromophenyl)-5-ethyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C14H12BrNO3, CAS 1426661-62-2
6-(4-Bromophenyl)-5-ethyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1426661-62-2C14H12BrNO3
6-(3,4-Dimethoxyphenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C15H14N2O3, CAS 235100-55-7
6-(3,4-Dimethoxyphenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 235100-55-7C15H14N2O3
6-(3,5-Dichlorophenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C13H8Cl2N2O, CAS 1956376-45-6
6-(3,5-Dichlorophenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1956376-45-6C13H8Cl2N2O
6-(3,5-Difluorophenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C13H8F2N2O, CAS 1956325-51-1
6-(3,5-Difluorophenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1956325-51-1C13H8F2N2O
6-(3,5-Dimethoxyphenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C15H14N2O3, CAS 1956376-47-8
6-(3,5-Dimethoxyphenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1956376-47-8C15H14N2O3
Dac-2-25 chemical structure, C14H16N2O, CAS 1675245-09-6
Dac-2-25
CAS 1675245-09-6C14H16N2O
6-(3,5-Difluorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid chemical structure, C12H7F2NO3, CAS 1525510-86-4
6-(3,5-Difluorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid
CAS 1525510-86-4C12H7F2NO3
6-(3,5-Dimethylphenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid chemical structure, C14H13NO3, CAS 1557830-18-8
6-(3,5-Dimethylphenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid
CAS 1557830-18-8C14H13NO3
3-Amino-1-methyl-6-(4-methylphenyl)-2(1H)-pyridinone chemical structure, C13H14N2O, CAS 1225672-07-0
3-Amino-1-methyl-6-(4-methylphenyl)-2(1H)-pyridinone
CAS 1225672-07-0C13H14N2O
3-(Aminomethyl)-1-(butan-2-yl)-6-(4-ethylphenyl)-4-methylpyridin-2(1H)-one chemical structure, C19H26N2O, CAS 1267172-88-2
3-(Aminomethyl)-1-(butan-2-yl)-6-(4-ethylphenyl)-4-methylpyridin-2(1H)-one
CAS 1267172-88-2C19H26N2O
1-Methyl-2-oxo-6-phenyl-1,2-dihydropyridine-4-carboxylic acid chemical structure, C13H11NO3, CAS 1368729-11-6
1-Methyl-2-oxo-6-phenyl-1,2-dihydropyridine-4-carboxylic acid
CAS 1368729-11-6C13H11NO3
6-(4-Fluorophenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid chemical structure, C13H10FNO3, CAS 1368556-31-3
6-(4-Fluorophenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
CAS 1368556-31-3C13H10FNO3
6-(4-Methoxyphenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid chemical structure, C14H13NO4, CAS 1368400-32-1
6-(4-Methoxyphenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
CAS 1368400-32-1C14H13NO4
6-(2-Methoxyphenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid chemical structure, C14H13NO4, CAS 1368510-71-7
6-(2-Methoxyphenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
CAS 1368510-71-7C14H13NO4
6-(3-Methoxyphenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid chemical structure, C14H13NO4, CAS 1368982-86-8
6-(3-Methoxyphenyl)-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
CAS 1368982-86-8C14H13NO4
3-Acetyl-6-(2-methoxyphenyl)pyridin-2(1H)-one chemical structure, C14H13NO3, CAS 1517188-98-5
3-Acetyl-6-(2-methoxyphenyl)pyridin-2(1H)-one
CAS 1517188-98-5C14H13NO3
2-Oxo-6-phenyl-1,2-dihydropyridine-3-carbaldehyde chemical structure, C12H9NO2, CAS 1501955-97-0
2-Oxo-6-phenyl-1,2-dihydropyridine-3-carbaldehyde
CAS 1501955-97-0C12H9NO2
5-Bromo-1,2-dihydro-2-oxo-6-phenyl-3-pyridinecarboxylic acid chemical structure, C12H8BrNO3, CAS 1710675-13-0
5-Bromo-1,2-dihydro-2-oxo-6-phenyl-3-pyridinecarboxylic acid
CAS 1710675-13-0C12H8BrNO3
4-(Trifluoromethyl)-2-hydroxy-6-(2-methoxy-5-methylphenyl)pyridine-3-carbonitrile chemical structure, C15H11F3N2O2, CAS 925006-91-3
4-(Trifluoromethyl)-2-hydroxy-6-(2-methoxy-5-methylphenyl)pyridine-3-carbonitrile
CAS 925006-91-3C15H11F3N2O2
6-(5-Chloro-2-methoxyphenyl)-4-(trifluoromethyl)-2-hydroxypyridine-3-carbonitrile chemical structure, C14H8ClF3N2O2, CAS 925006-93-5
6-(5-Chloro-2-methoxyphenyl)-4-(trifluoromethyl)-2-hydroxypyridine-3-carbonitrile
CAS 925006-93-5C14H8ClF3N2O2
6-(5-Ethyl-2-methoxyphenyl)-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinecarbonitrile chemical structure, C16H13F3N2O2, CAS 925006-97-9
6-(5-Ethyl-2-methoxyphenyl)-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinecarbonitrile
CAS 925006-97-9C16H13F3N2O2
6-(5-Fluoro-2-methoxyphenyl)-4-(trifluoromethyl)-2-hydroxypyridine-3-carbonitrile chemical structure, C14H8F4N2O2, CAS 925006-95-7
6-(5-Fluoro-2-methoxyphenyl)-4-(trifluoromethyl)-2-hydroxypyridine-3-carbonitrile
CAS 925006-95-7C14H8F4N2O2
Methyl 1,2-dihydro-6-[4-(methylthio)phenyl]-2-oxo-4-pyridinecarboxylate chemical structure, C14H13NO3S, CAS 925004-58-6
Methyl 1,2-dihydro-6-[4-(methylthio)phenyl]-2-oxo-4-pyridinecarboxylate
CAS 925004-58-6C14H13NO3S
Methyl 6-(4-bromophenyl)-3-cyano-2-hydroxypyridine-4-carboxylate chemical structure, C14H9BrN2O3, CAS 925004-03-1
Methyl 6-(4-bromophenyl)-3-cyano-2-hydroxypyridine-4-carboxylate
CAS 925004-03-1C14H9BrN2O3