CompoundList
Sign in
Murcko scaffold

1,8-Dioxaspiro[4.5]decane scaffold

47 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
47
With full pages
6
Scaffold SMILES

C1COC2(C1)CCOCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,8-Dioxaspiro[4.5]decane page
Murcko scaffold C1COC2(C1)CCOCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 47 of 47 chemicals

(2-Ethyl-1,8-dioxaspiro[4.5]decan-2-yl)methanol chemical structure, C11H20O3, CAS 88664-43-1
(2-Ethyl-1,8-dioxaspiro[4.5]decan-2-yl)methanol
CAS 88664-43-1C11H20O3
1,8-Dioxaspiro[4.5]decane chemical structure, C8H14O2, CAS 176-93-2
1,8-Dioxaspiro[4.5]decane
CAS 176-93-2C8H14O2
1,8-Dioxaspiro[4.5]decan-4-amine chemical structure, C8H15NO2, CAS 1779730-52-7
1,8-Dioxaspiro[4.5]decan-4-amine
CAS 1779730-52-7C8H15NO2
{1,8-Dioxaspiro[4.5]decan-4-yl}methanamine chemical structure, C9H17NO2, CAS 1784415-85-5
{1,8-Dioxaspiro[4.5]decan-4-yl}methanamine
CAS 1784415-85-5C9H17NO2
1,8-Dioxaspiro[4.5]decane-4-carboxylic acid chemical structure, C9H14O4, CAS 1785247-75-7
1,8-Dioxaspiro[4.5]decane-4-carboxylic acid
CAS 1785247-75-7C9H14O4
2-(Bromomethyl)-1,8-dioxaspiro(4.5)decane chemical structure, C9H15BrO2, CAS 1851527-23-5
2-(Bromomethyl)-1,8-dioxaspiro(4.5)decane
CAS 1851527-23-5C9H15BrO2
{1,8-Dioxaspiro[4.5]decan-2-yl}methanol chemical structure, C9H16O3, CAS 1864407-98-6
{1,8-Dioxaspiro[4.5]decan-2-yl}methanol
CAS 1864407-98-6C9H16O3
{7-Methyl-1,8-dioxaspiro[4.5]decan-2-yl}methanol chemical structure, C10H18O3, CAS 1878889-89-4
{7-Methyl-1,8-dioxaspiro[4.5]decan-2-yl}methanol
CAS 1878889-89-4C10H18O3
1,8-Dioxaspiro(4.5)decane-2-carboxylic acid chemical structure, C9H14O4, CAS 1864142-23-3
1,8-Dioxaspiro(4.5)decane-2-carboxylic acid
CAS 1864142-23-3C9H14O4
{1,8-Dioxaspiro[4.5]decan-2-yl}methanamine chemical structure, C9H17NO2, CAS 1862994-34-0
{1,8-Dioxaspiro[4.5]decan-2-yl}methanamine
CAS 1862994-34-0C9H17NO2
2-(Iodomethyl)-1,8-dioxaspiro[4.5]decane chemical structure, C9H15IO2, CAS 1878292-67-1
2-(Iodomethyl)-1,8-dioxaspiro[4.5]decane
CAS 1878292-67-1C9H15IO2
{7-Methyl-1,8-dioxaspiro[4.5]decan-2-yl}methanamine chemical structure, C10H19NO2, CAS 1864071-87-3
{7-Methyl-1,8-dioxaspiro[4.5]decan-2-yl}methanamine
CAS 1864071-87-3C10H19NO2
1,8-Dioxaspiro[4.5]decane-2-carbaldehyde chemical structure, C9H14O3, CAS 1872789-41-7
1,8-Dioxaspiro[4.5]decane-2-carbaldehyde
CAS 1872789-41-7C9H14O3
{1,8-Dioxaspiro[4.5]decan-2-yl}methanamine hydrochloride chemical structure, C9H18ClNO2, CAS 2126161-22-4
{1,8-Dioxaspiro[4.5]decan-2-yl}methanamine hydrochloride
CAS 2126161-22-4C9H18ClNO2
tert-Butyl N-{1,8-dioxaspiro[4.5]decan-3-yl}-N-methylcarbamate chemical structure, C14H25NO4, CAS 2059965-57-8
tert-Butyl N-{1,8-dioxaspiro[4.5]decan-3-yl}-N-methylcarbamate
CAS 2059965-57-8C14H25NO4
tert-Butyl N-methyl-N-{7-methyl-1,8-dioxaspiro[4.5]decan-3-yl}carbamate chemical structure, C15H27NO4, CAS 2060036-61-3
tert-Butyl N-methyl-N-{7-methyl-1,8-dioxaspiro[4.5]decan-3-yl}carbamate
CAS 2060036-61-3C15H27NO4
tert-Butyl N-{6-methoxy-1,8-dioxaspiro[4.5]decan-3-yl}-N-methylcarbamate chemical structure, C15H27NO5, CAS 2059933-20-7
tert-Butyl N-{6-methoxy-1,8-dioxaspiro[4.5]decan-3-yl}-N-methylcarbamate
CAS 2059933-20-7C15H27NO5
{1,8-Dioxaspiro[4.5]decan-2-yl}methanesulfonamide chemical structure, C9H17NO4S, CAS 2248330-13-2
{1,8-Dioxaspiro[4.5]decan-2-yl}methanesulfonamide
CAS 2248330-13-2C9H17NO4S
1,8-Dioxaspiro[4.5]decan-2-ylmethanesulfonyl chloride chemical structure, C9H15ClO4S, CAS 2166999-86-4
1,8-Dioxaspiro[4.5]decan-2-ylmethanesulfonyl chloride
CAS 2166999-86-4C9H15ClO4S
1,8-Dioxaspiro(4.5)decan-3-amine hydrochloride chemical structure, C8H16ClNO2, CAS 2411279-28-0
1,8-Dioxaspiro(4.5)decan-3-amine hydrochloride
CAS 2411279-28-0C8H16ClNO2
1,8-Dioxaspiro[4.5]decan-3-amine chemical structure, C8H15NO2, CAS 2001418-88-6
1,8-Dioxaspiro[4.5]decan-3-amine
CAS 2001418-88-6C8H15NO2
1-{1,8-Dioxaspiro[4.5]decan-4-yl}methanamine hydrochloride chemical structure, C9H18ClNO2, CAS 2411245-60-6
1-{1,8-Dioxaspiro[4.5]decan-4-yl}methanamine hydrochloride
CAS 2411245-60-6C9H18ClNO2
(3S,4R)-3-Azido-1,8-dioxaspiro[4.5]decan-4-ol chemical structure, C8H13N3O3, CAS 2550997-12-9
(3S,4R)-3-Azido-1,8-dioxaspiro[4.5]decan-4-ol
CAS 2550997-12-9C8H13N3O3
rac-(3R,4S)-4-Methoxy-1,8-dioxaspiro[4.5]decan-3-amine hydrochloride chemical structure, C9H18ClNO3, CAS 2550997-73-2
rac-(3R,4S)-4-Methoxy-1,8-dioxaspiro[4.5]decan-3-amine hydrochloride
CAS 2550997-73-2C9H18ClNO3