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Murcko scaffold

4,6-Diphenyl-1H-pyridine-2-thione scaffold

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
19
With full pages
4
Scaffold SMILES

S=c1cc(-c2ccccc2)cc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,6-Diphenyl-1H-pyridine-2-thione page
Murcko scaffold S=c1cc(-c2ccccc2)cc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

3-Pyridinecarbonitrile, 1,2-dihydro-4-(4-chlorophenyl)-6-phenyl-2-thioxo- chemical structure, C18H11ClN2S, CAS 78564-16-6
3-Pyridinecarbonitrile, 1,2-dihydro-4-(4-chlorophenyl)-6-phenyl-2-thioxo-
CAS 78564-16-6C18H11ClN2S
4-(4-Methoxy-phenyl)-6-phenyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile chemical structure, C19H14N2OS, CAS 78564-17-7
4-(4-Methoxy-phenyl)-6-phenyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile
CAS 78564-17-7C19H14N2OS
1,2-Dihydro-4,6-diphenyl-2-thioxo-3-pyridinecarbonitrile chemical structure, C18H12N2S, CAS 58327-74-5
1,2-Dihydro-4,6-diphenyl-2-thioxo-3-pyridinecarbonitrile
CAS 58327-74-5C18H12N2S
2-Mercapto-6-(4-methoxyphenyl)-4-phenylnicotinonitrile chemical structure, C19H14N2OS, CAS 78564-18-8
2-Mercapto-6-(4-methoxyphenyl)-4-phenylnicotinonitrile
CAS 78564-18-8C19H14N2OS
4-(2-Chlorophenyl)-2-mercapto-6-phenylnicotinonitrile chemical structure, C18H11ClN2S, CAS 19-16-9
4-(2-Chlorophenyl)-2-mercapto-6-phenylnicotinonitrile
CAS 19-16-9C18H11ClN2S
1,2-Dihydro-4-(4-methylphenyl)-6-phenyl-2-thioxo-3-pyridinecarbonitrile chemical structure, C19H14N2S, CAS 332126-96-2
1,2-Dihydro-4-(4-methylphenyl)-6-phenyl-2-thioxo-3-pyridinecarbonitrile
CAS 332126-96-2C19H14N2S
4-Phenyl-2-thioxo-6-p-tolyl-1,2-dihydro-pyridine-3-carbonitrile chemical structure, C19H14N2S, CAS 78564-19-9
4-Phenyl-2-thioxo-6-p-tolyl-1,2-dihydro-pyridine-3-carbonitrile
CAS 78564-19-9C19H14N2S
4,6-Diphenyl-1H-pyridine-2-thione chemical structure, C17H13NS, CAS 62219-32-3
4,6-Diphenyl-1H-pyridine-2-thione
CAS 62219-32-3C17H13NS
3-Pyridinecarbonitrile, 1,2-dihydro-4-(3-nitrophenyl)-6-phenyl-2-thioxo- chemical structure, C18H11N3O2S, CAS 89451-45-6
3-Pyridinecarbonitrile, 1,2-dihydro-4-(3-nitrophenyl)-6-phenyl-2-thioxo-
CAS 89451-45-6C18H11N3O2S
3-Pyridinecarbonitrile, 1,2-dihydro-4-(2-(difluoromethoxy)phenyl)-6-phenyl-2-thioxo- chemical structure, C19H12F2N2OS, CAS 78578-72-0
3-Pyridinecarbonitrile, 1,2-dihydro-4-(2-(difluoromethoxy)phenyl)-6-phenyl-2-thioxo-
CAS 78578-72-0C19H12F2N2OS
3-Pyridinecarbonitrile, 4-(4-fluorophenyl)-1,2-dihydro-6-phenyl-2-thioxo- chemical structure, C18H11FN2S, CAS 89451-46-7
3-Pyridinecarbonitrile, 4-(4-fluorophenyl)-1,2-dihydro-6-phenyl-2-thioxo-
CAS 89451-46-7C18H11FN2S
Ethyl 4-(4-chlorophenyl)-5-cyano-1,6-dihydro-2-phenyl-6-thioxo-3-pyridinecarboxylate chemical structure, C21H15ClN2O2S, CAS 105199-63-1
Ethyl 4-(4-chlorophenyl)-5-cyano-1,6-dihydro-2-phenyl-6-thioxo-3-pyridinecarboxylate
CAS 105199-63-1C21H15ClN2O2S
1-Amino-4,6-diphenylpyridine-2(1H)-thione chemical structure, C17H14N2S, CAS 70965-50-3
1-Amino-4,6-diphenylpyridine-2(1H)-thione
CAS 70965-50-3C17H14N2S
4,6-Diphenyl-2-sulfanylidene-1,2-dihydropyridine-3,5-dicarbonitrile chemical structure, C19H11N3S, CAS 86625-29-8
4,6-Diphenyl-2-sulfanylidene-1,2-dihydropyridine-3,5-dicarbonitrile
CAS 86625-29-8C19H11N3S
1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione chemical structure, C19H17NOS, CAS 96185-26-1
1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione
CAS 96185-26-1C19H17NOS
2-Mercapto-4,6-bis(4-methoxyphenyl)nicotinonitrile chemical structure, C20H16N2O2S, CAS 128342-39-2
2-Mercapto-4,6-bis(4-methoxyphenyl)nicotinonitrile
CAS 128342-39-2C20H16N2O2S
2-Mercapto-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile chemical structure, C20H16N2OS, CAS 917561-70-7
2-Mercapto-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile
CAS 917561-70-7C20H16N2OS
6-(4-Fluorophenyl)-1,2-dihydro-4-(4-methoxyphenyl)-2-thioxo-3-pyridinecarbonitrile chemical structure, C19H13FN2OS, CAS 885270-02-0
6-(4-Fluorophenyl)-1,2-dihydro-4-(4-methoxyphenyl)-2-thioxo-3-pyridinecarbonitrile
CAS 885270-02-0C19H13FN2OS
6-(3,4-Dimethylphenyl)-2-mercapto-4-(4-methoxyphenyl)nicotinonitrile chemical structure, C21H18N2OS, CAS 885270-05-3
6-(3,4-Dimethylphenyl)-2-mercapto-4-(4-methoxyphenyl)nicotinonitrile
CAS 885270-05-3C21H18N2OS