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Murcko scaffold

3-(1H-Imidazol-2-yl)pyridine scaffold

76 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 76
With full pages: 6

Scaffold SMILES

c1cncc(-c2ncc[nH]2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 3-(1H-Imidazol-2-yl)pyridine page

Murcko scaffold c1cncc(-c2ncc[nH]2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 76 of 76 chemicals

2-(4-Methyl-3-pyridyl)imidazole-5-carbaldehyde chemical structure, C10H9N3O, CAS 1596856-34-6

2-(4-Methyl-3-pyridyl)imidazole-5-carbaldehyde

CAS 1596856-34-6C₁₀H₉N₃O

2-(6-Methoxy-3-pyridyl)imidazole-5-methanol chemical structure, C10H11N3O2, CAS 1599122-39-0

2-(6-Methoxy-3-pyridyl)imidazole-5-methanol

CAS 1599122-39-0C₁₀H₁₁N₃O₂

5-(1-Methyl-1H-imidazol-2-yl)pyridine-3-carbaldehyde chemical structure, C10H9N3O, CAS 1600303-12-5

5-(1-Methyl-1H-imidazol-2-yl)pyridine-3-carbaldehyde

CAS 1600303-12-5C₁₀H₉N₃O

2-(6-Bromo-3-pyridinyl)-N,N-dimethyl-1H-imidazole-5-carboxamide chemical structure, C11H11BrN4O, CAS 1516936-05-2

2-(6-Bromo-3-pyridinyl)-N,N-dimethyl-1H-imidazole-5-carboxamide

CAS 1516936-05-2C₁₁H₁₁BrN₄O

2-Chloro-5-(5-chloro-1H-imidazol-2-yl)pyridine chemical structure, C8H5Cl2N3, CAS 1516951-57-7

2-Chloro-5-(5-chloro-1H-imidazol-2-yl)pyridine

CAS 1516951-57-7C₈H₅Cl₂N₃

2-Chloro-5-[4-chloro-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imidazol-2-yl]pyridine chemical structure, C14H19Cl2N3OSi, CAS 1516935-50-4

2-Chloro-5-[4-chloro-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imidazol-2-yl]pyridine

CAS 1516935-50-4C₁₄H₁₉Cl₂N₃OSi

3-Chloro-5-(1H-imidazol-2-yl)pyridine chemical structure, C8H6ClN3, CAS 1211589-64-8

3-Chloro-5-(1H-imidazol-2-yl)pyridine

CAS 1211589-64-8C₈H₆ClN₃

2-Bromo-3-(1H-imidazol-2-yl)-6-(trifluoromethyl)pyridine chemical structure, C9H5BrF3N3, CAS 1211515-72-8

2-Bromo-3-(1H-imidazol-2-yl)-6-(trifluoromethyl)pyridine

CAS 1211515-72-8C₉H₅BrF₃N₃

2-Chloro-5-(1H-imidazol-2-yl)-3-(trifluoromethyl)pyridine chemical structure, C9H5ClF3N3, CAS 1211536-85-4

2-Chloro-5-(1H-imidazol-2-yl)-3-(trifluoromethyl)pyridine

CAS 1211536-85-4C₉H₅ClF₃N₃

2-(6-Chloropyridin-3-yl)-4-methyl-1H-imidazole-5-carboxylic acid chemical structure, C10H8ClN3O2, CAS 1823244-41-2

2-(6-Chloropyridin-3-yl)-4-methyl-1H-imidazole-5-carboxylic acid

CAS 1823244-41-2C₁₀H₈ClN₃O₂

2-Bromo-5-(1H-imidazol-2-yl)pyridine chemical structure, C8H6BrN3, CAS 1211583-15-1

2-Bromo-5-(1H-imidazol-2-yl)pyridine

CAS 1211583-15-1C₈H₆BrN₃

2-Methoxy-3-(5-methyl-2-imidazolyl)pyridine chemical structure, C10H11N3O, CAS 1862868-53-8

2-Methoxy-3-(5-methyl-2-imidazolyl)pyridine

CAS 1862868-53-8C₁₀H₁₁N₃O

2-Methoxy-5-(5-methyl-2-imidazolyl)pyridine chemical structure, C10H11N3O, CAS 1866859-90-6

2-Methoxy-5-(5-methyl-2-imidazolyl)pyridine

CAS 1866859-90-6C₁₀H₁₁N₃O

4-Methyl-2-(pyridin-3-yl)-1H-imidazole-5-carboxylic acid dihydrochloride chemical structure, C10H11Cl2N3O2, CAS 2172503-56-7

4-Methyl-2-(pyridin-3-yl)-1H-imidazole-5-carboxylic acid dihydrochloride

CAS 2172503-56-7C₁₀H₁₁Cl₂N₃O₂

(5-(1H-Imidazol-2-yl)pyridin-3-yl)boronic acid chemical structure, C8H8BN3O2, CAS 2256747-82-5

(5-(1H-Imidazol-2-yl)pyridin-3-yl)boronic acid

CAS 2256747-82-5C₈H₈BN₃O₂

N-(1-Cyanobutyl)-5-methyl-2-pyridin-3-yl-1H-imidazole-4-carboxamide chemical structure, C15H17N5O, CAS 2249434-08-8

N-(1-Cyanobutyl)-5-methyl-2-pyridin-3-yl-1H-imidazole-4-carboxamide

CAS 2249434-08-8C₁₅H₁₇N₅O

2-(6-Chloro-pyridin-3-yl)-1,5-dimethyl-1H-imidazole-4-carboxylic acid ethyl ester chemical structure, C13H14ClN3O2, CAS 2514967-29-2

2-(6-Chloro-pyridin-3-yl)-1,5-dimethyl-1H-imidazole-4-carboxylic acid ethyl ester

CAS 2514967-29-2C₁₃H₁₄ClN₃O₂

2-Bromo-5-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)pyridine chemical structure, C10H7BrF3N3, CAS 2873378-19-7

2-Bromo-5-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)pyridine

CAS 2873378-19-7C₁₀H₇BrF₃N₃

5-(1-Methyl-1H-imidazol-2-yl)pyridine-2-carbaldehyde chemical structure, C10H9N3O, CAS 2138302-92-6

5-(1-Methyl-1H-imidazol-2-yl)pyridine-2-carbaldehyde

CAS 2138302-92-6C₁₀H₉N₃O

4-Methyl-5-(1-methyl-1H-imidazol-2-yl)pyridin-3-amine chemical structure, C10H12N4, CAS 2137742-84-6

4-Methyl-5-(1-methyl-1H-imidazol-2-yl)pyridin-3-amine

CAS 2137742-84-6C₁₀H₁₂N₄

3-(1H-Imidazol-2-yl)-4-methylpyridin-2-amine chemical structure, C9H10N4, CAS 2137709-29-4

3-(1H-Imidazol-2-yl)-4-methylpyridin-2-amine

CAS 2137709-29-4C₉H₁₀N₄

2,3,6-Trifluoro-5-(1-methyl-1H-imidazol-2-yl)pyridine chemical structure, C9H6F3N3, CAS 2138081-60-2

2,3,6-Trifluoro-5-(1-methyl-1H-imidazol-2-yl)pyridine

CAS 2138081-60-2C₉H₆F₃N₃

3-(1-Ethyl-1H-imidazol-2-yl)-2,5,6-trifluoropyridine chemical structure, C10H8F3N3, CAS 2138061-56-8

3-(1-Ethyl-1H-imidazol-2-yl)-2,5,6-trifluoropyridine

CAS 2138061-56-8C₁₀H₈F₃N₃

2-Fluoro-5-(1-methyl-1H-imidazol-2-yl)pyridine chemical structure, C9H8FN3, CAS 2137761-82-9

2-Fluoro-5-(1-methyl-1H-imidazol-2-yl)pyridine

CAS 2137761-82-9C₉H₈FN₃