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Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(NC1CCN(Cc2ccccc2)C1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCN(Cc2ccccc2)C1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-(1-Benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide chemical structure, C21H26ClN3O2, CAS 70325-83-6
N-(1-Benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide
CAS 70325-83-6C21H26ClN3O2
Nemonapride chemical structure, C21H26ClN3O2, CAS 75272-39-8
Nemonapride
CAS 75272-39-8C21H26ClN3O2
YM-08050 chemical structure, C20H24ClN3O2, CAS 73328-60-6
YM-08050
CAS 73328-60-6C20H24ClN3O2
trans-Nemonapride chemical structure, C21H26ClN3O2, CAS 752154-64-6
trans-Nemonapride
CAS 752154-64-6C21H26ClN3O2
SB-436811 chemical structure, C23H29Cl2N3O2, CAS 346729-66-6
SB-436811
CAS 346729-66-6C23H29Cl2N3O2
N-((3R,4R)-1-Benzyl-4-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide chemical structure, C21H26ClN3O2, CAS 75272-47-8
N-((3R,4R)-1-Benzyl-4-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide
CAS 75272-47-8C21H26ClN3O2
N-(1-Benzylpyrrolidin-3-yl)-2-fluorobenzamide chemical structure, C18H19FN2O, CAS 1031205-66-9
N-(1-Benzylpyrrolidin-3-yl)-2-fluorobenzamide
CAS 1031205-66-9C18H19FN2O
5-Chloro-N-[(2R,3R)-1-[dideuterio(phenyl)methyl]-2-methylpyrrolidin-3-yl]-2-methoxy-4-(trideuteriomethylamino)benzamide chemical structure, C21H26ClN3O2, CAS 2950168-16-6
5-Chloro-N-[(2R,3R)-1-[dideuterio(phenyl)methyl]-2-methylpyrrolidin-3-yl]-2-methoxy-4-(trideuteriomethylamino)benzamide
CAS 2950168-16-6C21H26ClN3O2