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Heterocyclic building blocks

Isomorphine

Also known as alpha-Isomorphine, (5alpha,6beta)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol, Morphinan-3,6-beta-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-

CAS 143-70-4Formula C17H19NO3Molar mass 285.34 g/molEC 205-607-6
Prohibited, not for trade
Why it is not for trade
Isomorphine chemical structure, C17H19NO3, CAS 143-70-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
143-70-4
Formula
C17H19NO3
Molar mass
285.34 g/mol
EC number
205-607-6
HS code
293499
Category
Heterocyclic building blocks

What is Isomorphine?

Plain description, key identifiers and synonyms

(5alpha,6beta)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol has been reported in Papaver somniferum.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4R,4aR,7R,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
CAS number
143-70-4
EC number
205-607-6
Molecular formula
C17H19NO3
InChIKey
BQJCRHHNABKAKU-NOSXKOESSA-N
InChI
InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13+,16-,17-/m0/s1
Canonical SMILES
CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5
Isomeric SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@@H](C=C4)O

Synonyms

  • alpha-Isomorphine
  • (5alpha,6beta)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
  • Morphinan-3,6-beta-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-
  • 17-Methyl-5alpha-7,8-didehydro-4,5-epoxymorphinan-3,6beta-diol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
285.34 g/molcalc.
Exact mass
285.1365 Dacalc.
LogP (octanol/water)
1.2calc.
Topological polar surface area
52.93 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
21calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.53calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O5

C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O5

5 rings, 18 atoms.

246 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Isomorphine suppliers

Trading restrictions apply to this substance

Narcotic drug

Isomorphine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961, HS 2022 subheading 2939.11 (opium alkaloids and their derivatives)

Our policy on controlled substances

Isomorphine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

Narcotic drug

Isomorphine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961, HS 2022 subheading 2939.11 (opium alkaloids and their derivatives)

Our policy on controlled substances

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Isomorphine is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Isomorphine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Isomorphine, based on the data on this page

What is Isomorphine?

(5alpha,6beta)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol has been reported in Papaver somniferum.

What is the CAS number of Isomorphine?

The CAS registry number of Isomorphine is 143-70-4.

What is the molecular formula and weight of Isomorphine?

The molecular formula of Isomorphine is C17H19NO3 and its molar mass is 285.34 g/mol.

What is Isomorphine used for?

Known uses and roles of Isomorphine include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Isomorphine hazardous?

No GHS hazard classification for Isomorphine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Isomorphine?

Isomorphine is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Isomorphine on CompoundList?

No. Isomorphine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Isomorphine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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