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Murcko scaffold

Ring system with 3 rings and 20 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
13
With full pages
5
Scaffold SMILES

c1ccc(CCC2CCC(C3CCCCC3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCC2CCC(C3CCCCC3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Benzene, 1,2-difluoro-4-[2-(4'-pentyl[1,1'-bicyclohexyl]-4-yl)ethyl]- chemical structure, C25H38F2, CAS 107215-67-8
Benzene, 1,2-difluoro-4-[2-(4'-pentyl[1,1'-bicyclohexyl]-4-yl)ethyl]-
CAS 107215-67-8C25H38F2
Benzene, 1-[2-(4'-pentyl[1,1'-bicyclohexyl]-4-yl)ethyl]-4-(trifluoromethoxy)- chemical structure, C26H39F3O, CAS 133914-50-8
Benzene, 1-[2-(4'-pentyl[1,1'-bicyclohexyl]-4-yl)ethyl]-4-(trifluoromethoxy)-
CAS 133914-50-8C26H39F3O
Benzene, 1-[2-(4'-propyl[1,1'-bicyclohexyl]-4-yl)ethyl]-4-(trifluoromethoxy)- chemical structure, C24H35F3O, CAS 121219-85-0
Benzene, 1-[2-(4'-propyl[1,1'-bicyclohexyl]-4-yl)ethyl]-4-(trifluoromethoxy)-
CAS 121219-85-0C24H35F3O
tFPEt5bcH chemical structure, C25H37F3, CAS 144583-01-7
tFPEt5bcH
CAS 144583-01-7C25H37F3
(1r,1's,4r,4'r)-4-[2-(4-Fluorophenyl)ethyl]-4'-propyl-1,1'-bi(cyclohexane) chemical structure, C23H35F, CAS 97941-21-4
(1r,1's,4r,4'r)-4-[2-(4-Fluorophenyl)ethyl]-4'-propyl-1,1'-bi(cyclohexane)
CAS 97941-21-4C23H35F
1,2-Difluoro-4-(2-((trans,trans)-4'-propyl(1,1'-bicyclohexyl)-4-yl)ethyl)benzene chemical structure, C23H34F2, CAS 107215-66-7
1,2-Difluoro-4-(2-((trans,trans)-4'-propyl(1,1'-bicyclohexyl)-4-yl)ethyl)benzene
CAS 107215-66-7C23H34F2
4-[2-[(Trans,trans)-4a(2)-propyl[1,1a(2)-bicyclohexyl]-4-yl]ethyl]benzonitrile chemical structure, C24H35N, CAS 116020-37-2
4-[2-[(Trans,trans)-4a(2)-propyl[1,1a(2)-bicyclohexyl]-4-yl]ethyl]benzonitrile
CAS 116020-37-2C24H35N
1-Fluoro-4-[2-[(trans,trans)-4a(2)-pentyl[1,1a(2)-bicyclohexyl]-4-yl]ethyl]benzene chemical structure, C25H39F, CAS 116020-40-7
1-Fluoro-4-[2-[(trans,trans)-4a(2)-pentyl[1,1a(2)-bicyclohexyl]-4-yl]ethyl]benzene
CAS 116020-40-7C25H39F
(1s,1'r,4r,4'r)-4-Propyl-4'-[2-(3,4,5-trifluorophenyl)ethyl]-1,1'-bi(cyclohexane) chemical structure, C23H33F3, CAS 131819-25-5
(1s,1'r,4r,4'r)-4-Propyl-4'-[2-(3,4,5-trifluorophenyl)ethyl]-1,1'-bi(cyclohexane)
CAS 131819-25-5C23H33F3
4-[2-(4-Ethoxy-2,3-difluorophenyl)ethyl]-4'-propyl-1,1'-bi(cyclohexane) chemical structure, C25H38F2O, CAS 2983457-29-8
4-[2-(4-Ethoxy-2,3-difluorophenyl)ethyl]-4'-propyl-1,1'-bi(cyclohexane)
CAS 2983457-29-8C25H38F2O
1-Ethyl-4-[2-[(trans,trans)-4a(2)-propyl[1,1a(2)-bicyclohexyl]-4-yl]ethyl]benzene chemical structure, C25H40, CAS 121553-94-4
1-Ethyl-4-[2-[(trans,trans)-4a(2)-propyl[1,1a(2)-bicyclohexyl]-4-yl]ethyl]benzene
CAS 121553-94-4C25H40
(1r,1's,4r,4'r)-4-[2-(4-Pentylphenyl)ethyl]-4'-propyl-1,1'-bi(cyclohexane) chemical structure, C28H46, CAS 121553-95-5
(1r,1's,4r,4'r)-4-[2-(4-Pentylphenyl)ethyl]-4'-propyl-1,1'-bi(cyclohexane)
CAS 121553-95-5C28H46
tFPEt4bcH chemical structure, C24H35F3, CAS 171362-73-5
tFPEt4bcH
CAS 171362-73-5C24H35F3