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Murcko scaffold

Ring system with 3 rings and 16 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
18
With full pages
4
Scaffold SMILES

c1ccc(Cc2nc3ncncc3[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2nc3ncncc3[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Phenyl(7H-purin-8-yl)methanol chemical structure, C12H10N4O, CAS 2836-31-9
Phenyl(7H-purin-8-yl)methanol
CAS 2836-31-9C12H10N4O
[2-(Methylsulfanyl)-7H-purin-8-yl](phenyl)methanol chemical structure, C13H12N4OS, CAS 4244-51-3
[2-(Methylsulfanyl)-7H-purin-8-yl](phenyl)methanol
CAS 4244-51-3C13H12N4OS
(2-Amino-7H-purin-8-yl)(phenyl)methanol chemical structure, C12H11N5O, CAS 4460-09-7
(2-Amino-7H-purin-8-yl)(phenyl)methanol
CAS 4460-09-7C12H11N5O
9-Butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine chemical structure, C19H25N5O3, CAS 352519-21-2
9-Butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine
CAS 352519-21-2C19H25N5O3
8-(2-Chloro-3,4,5-trimethoxy-benzyl)-2-fluoro-9-pent-4-ylnyl-9H-purin-6-ylamine chemical structure, C20H21ClFN5O3, CAS 422508-46-1
8-(2-Chloro-3,4,5-trimethoxy-benzyl)-2-fluoro-9-pent-4-ylnyl-9H-purin-6-ylamine
CAS 422508-46-1C20H21ClFN5O3
8-Benzyl-9H-purine-2,6-diamine chemical structure, C12H12N6, CAS 194613-27-9
8-Benzyl-9H-purine-2,6-diamine
CAS 194613-27-9C12H12N6
(6-(Methylthio)-9H-purin-8-yl)(phenyl)methanol chemical structure, C13H12N4OS, CAS 4460-08-6
(6-(Methylthio)-9H-purin-8-yl)(phenyl)methanol
CAS 4460-08-6C13H12N4OS
8-Benzyl-7H-purin-6-amine chemical structure, C12H11N5, CAS 30466-97-8
8-Benzyl-7H-purin-6-amine
CAS 30466-97-8C12H11N5
(6-Amino-2-methyl-7H-purin-8-yl)-phenylmethanol chemical structure, C13H13N5O, CAS 4244-52-4
(6-Amino-2-methyl-7H-purin-8-yl)-phenylmethanol
CAS 4244-52-4C13H13N5O
(2-Amino-6-methylsulfanyl-7H-purin-8-yl)-phenylmethanol chemical structure, C13H13N5OS, CAS 4460-10-0
(2-Amino-6-methylsulfanyl-7H-purin-8-yl)-phenylmethanol
CAS 4460-10-0C13H13N5OS
(6-Amino-7H-purin-8-yl)-phenylmethanol chemical structure, C12H11N5O, CAS 2260-33-5
(6-Amino-7H-purin-8-yl)-phenylmethanol
CAS 2260-33-5C12H11N5O
9-Butyl-8-(4-methoxybenzyl)-9H-purin-6-amine chemical structure, C17H21N5O, CAS 376629-53-7
9-Butyl-8-(4-methoxybenzyl)-9H-purin-6-amine
CAS 376629-53-7C17H21N5O
9-Butyl-8-(3-methoxybenzyl)-9H-purin-6-amine chemical structure, C17H21N5O, CAS 521308-67-8
9-Butyl-8-(3-methoxybenzyl)-9H-purin-6-amine
CAS 521308-67-8C17H21N5O
(6-Methyl-7H-purin-8-yl)-phenylmethanol chemical structure, C13H12N4O, CAS 4244-49-9
(6-Methyl-7H-purin-8-yl)-phenylmethanol
CAS 4244-49-9C13H12N4O
9-Propyl-8-[(3,4,5-trimethoxyphenyl)methyl]-9H-purin-6-amine chemical structure, C18H23N5O3, CAS 376629-07-1
9-Propyl-8-[(3,4,5-trimethoxyphenyl)methyl]-9H-purin-6-amine
CAS 376629-07-1C18H23N5O3
(E)-9-(But-2-en-1-yl)-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine chemical structure, C19H23N5O3, CAS 1454619-18-1
(E)-9-(But-2-en-1-yl)-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine
CAS 1454619-18-1C19H23N5O3
9-(Pent-4-yn-1-yl)-8-[(3,4,5-trimethoxyphenyl)methyl]-9H-purin-6-amine chemical structure, C20H23N5O3, CAS 376629-26-4
9-(Pent-4-yn-1-yl)-8-[(3,4,5-trimethoxyphenyl)methyl]-9H-purin-6-amine
CAS 376629-26-4C20H23N5O3
2-Fluoro-9-(2-isopropoxyethyl)-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine chemical structure, C20H26FN5O4, CAS 422508-27-8
2-Fluoro-9-(2-isopropoxyethyl)-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine
CAS 422508-27-8C20H26FN5O4