Murcko scaffold
Ring system with 3 rings and 22 atoms
81 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 22
- Chemicals
- 81
- With full pages
- 5
Scaffold SMILES
O=C(NC(=S)Nc1ccccc1)c1ccc2ccccc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 81 chemicals
![N-[(2-Fluorophenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C18H13FN2OS, CAS 445418-12-2](/s/SEJGOQNGCPANPV-UHFFFAOYSA-N.svg)
N-[(2-Fluorophenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 445418-12-2C18H13FN2OS
3-Methoxy-N-(phenylcarbamothioyl)naphthalene-2-carboxamide
CAS 364742-50-7C19H16N2O2S
![N-[[2-Chloro-5-(propanoylamino)phenyl]carbamothioyl]naphthalene-2-carboxamide chemical structure, C21H18ClN3O2S, CAS 667867-07-4](/s/DGWDTDLRCHREGB-UHFFFAOYSA-N.svg)
N-[[2-Chloro-5-(propanoylamino)phenyl]carbamothioyl]naphthalene-2-carboxamide
CAS 667867-07-4C21H18ClN3O2S
![N-[(4-Iodophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide chemical structure, C19H15IN2O2S, CAS 445418-71-3](/s/IPXSXCCYXWZENZ-UHFFFAOYSA-N.svg)
N-[(4-Iodophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide
CAS 445418-71-3C19H15IN2O2S
![Methyl 2-{[(2-naphthoylamino)carbonothioyl]amino}benzoate chemical structure, C20H16N2O3S, CAS 445420-44-0](/s/BALXJDJQPBFOIX-UHFFFAOYSA-N.svg)
Methyl 2-{[(2-naphthoylamino)carbonothioyl]amino}benzoate
CAS 445420-44-0C20H16N2O3S
![3-Methoxy-N-[[3-(propanoylamino)phenyl]carbamothioyl]naphthalene-2-carboxamide chemical structure, C22H21N3O3S, CAS 429636-90-8](/s/OHCDGWJNIROLCL-UHFFFAOYSA-N.svg)
3-Methoxy-N-[[3-(propanoylamino)phenyl]carbamothioyl]naphthalene-2-carboxamide
CAS 429636-90-8C22H21N3O3S
![3-Methoxy-N-[(4-methylphenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C20H18N2O2S, CAS 364597-05-7](/s/FEAUMYOEJAHGEY-UHFFFAOYSA-N.svg)
3-Methoxy-N-[(4-methylphenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 364597-05-7C20H18N2O2S
![3-Methoxy-N-[(3-methoxyphenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C20H18N2O3S, CAS 364616-27-3](/s/VLFZRRWDBUOZHX-UHFFFAOYSA-N.svg)
3-Methoxy-N-[(3-methoxyphenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 364616-27-3C20H18N2O3S
![N-[(2-Fluorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide chemical structure, C19H15FN2O2S, CAS 364601-60-5](/s/AQDJYDVUKUUWJQ-UHFFFAOYSA-N.svg)
N-[(2-Fluorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide
CAS 364601-60-5C19H15FN2O2S
![Methyl 2-[(3-methoxynaphthalene-2-carbonyl)carbamothioylamino]benzoate chemical structure, C21H18N2O4S, CAS 371130-59-5](/s/WMEVBXMMDNJWQM-UHFFFAOYSA-N.svg)
Methyl 2-[(3-methoxynaphthalene-2-carbonyl)carbamothioylamino]benzoate
CAS 371130-59-5C21H18N2O4S
![N-[(3,5-Dimethylphenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C20H18N2OS, CAS 431911-12-5](/s/DPYCQDAMPWVMEE-UHFFFAOYSA-N.svg)
N-[(3,5-Dimethylphenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 431911-12-5C20H18N2OS
![N-[(4-Acetylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide chemical structure, C21H18N2O3S, CAS 429655-62-9](/s/USMHLHGSSSJMMU-UHFFFAOYSA-N.svg)
N-[(4-Acetylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide
CAS 429655-62-9C21H18N2O3S
![3-Methoxy-N-[(4-methoxyphenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C20H18N2O3S, CAS 364596-64-5](/s/CFCSTJBKLTXCJY-UHFFFAOYSA-N.svg)
3-Methoxy-N-[(4-methoxyphenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 364596-64-5C20H18N2O3S
![4-Bromo-3-methoxy-N-[(2-methylphenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C20H17BrN2O2S, CAS 836664-39-2](/s/XJJHQVPIAJFKAC-UHFFFAOYSA-N.svg)
4-Bromo-3-methoxy-N-[(2-methylphenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 836664-39-2C20H17BrN2O2S
![N-[(2,4-Difluorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide chemical structure, C19H14F2N2O2S, CAS 445419-72-7](/s/QHVDFYBOUOUNGQ-UHFFFAOYSA-N.svg)
N-[(2,4-Difluorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide
CAS 445419-72-7C19H14F2N2O2S
4-Chloro-3-(naphthalene-2-carbonylcarbamothioylamino)benzoic acid
CAS 532415-85-3C19H13ClN2O3S
![N-[(4-Iodo-2-methylphenyl)carbamothioyl]naphthalene-2-carboxamide chemical structure, C19H15IN2OS, CAS 431980-97-1](/s/ZFKCRBOCQGEAHL-UHFFFAOYSA-N.svg)
N-[(4-Iodo-2-methylphenyl)carbamothioyl]naphthalene-2-carboxamide
CAS 431980-97-1C19H15IN2OS
![3-[(3-Methoxynaphthalene-2-carbonyl)carbamothioylamino]benzoic acid chemical structure, C20H16N2O4S, CAS 433966-33-7](/s/RZMQFHPIJAKKLT-UHFFFAOYSA-N.svg)
3-[(3-Methoxynaphthalene-2-carbonyl)carbamothioylamino]benzoic acid
CAS 433966-33-7C20H16N2O4S
![4-Methyl-3-{[(naphthalen-2-ylcarbonyl)carbamothioyl]amino}benzoic acid chemical structure, C20H16N2O3S, CAS 433971-93-8](/s/BOPDOPYBOBPKCM-UHFFFAOYSA-N.svg)
4-Methyl-3-{[(naphthalen-2-ylcarbonyl)carbamothioyl]amino}benzoic acid
CAS 433971-93-8C20H16N2O3S
![2-Chloro-5-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoic acid chemical structure, C20H15ClN2O4S, CAS 434302-90-6](/s/QYCRNMZTLHBBCS-UHFFFAOYSA-N.svg)
2-Chloro-5-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoic acid
CAS 434302-90-6C20H15ClN2O4S
![2-Chloro-4-{[(naphthalen-2-ylcarbonyl)carbamothioyl]amino}benzoic acid chemical structure, C19H13ClN2O3S, CAS 532956-40-4](/s/IJWCTKIHEGDWLQ-UHFFFAOYSA-N.svg)
2-Chloro-4-{[(naphthalen-2-ylcarbonyl)carbamothioyl]amino}benzoic acid
CAS 532956-40-4C19H13ClN2O3S
![4-Methoxy-3-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoic acid chemical structure, C21H18N2O5S, CAS 434304-96-8](/s/PUYQXSXXBMFZMG-UHFFFAOYSA-N.svg)
4-Methoxy-3-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoic acid
CAS 434304-96-8C21H18N2O5S
![2-Chloro-4-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoic acid chemical structure, C20H15ClN2O4S, CAS 690650-78-3](/s/FJRUZADTHGXIPL-UHFFFAOYSA-N.svg)
2-Chloro-4-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoic acid
CAS 690650-78-3C20H15ClN2O4S
![4-[(3-Methoxynaphthalene-2-carbonyl)carbamothioylamino]benzoic acid chemical structure, C20H16N2O4S, CAS 434287-01-1](/s/KSKPEOGMDRQSLQ-UHFFFAOYSA-N.svg)
4-[(3-Methoxynaphthalene-2-carbonyl)carbamothioylamino]benzoic acid
CAS 434287-01-1C20H16N2O4S
- 4-Methoxy-3-{[(naphthalen-2-ylcarbonyl)carbamothioyl]amino}benzoic acid434287-92-0C20H16N2O4S
- N-[(4-Fluoro-3-nitrophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide356079-64-6C19H14FN3O4S
- N-[(2-Fluoro-5-nitrophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide364625-94-5C19H14FN3O4S
- N-[(3,4-Dichlorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429634-59-3C19H14Cl2N2O2S
- N-[(4-Chlorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429637-65-0C19H15ClN2O2S
- 3-Methoxy-N-[[3-(trifluoromethyl)phenyl]carbamothioyl]naphthalene-2-carboxamide6586-18-1C20H15F3N2O2S
- N-[(2-Hydroxy-3,5-dimethylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429639-56-5C21H20N2O3S
- N-[(4-Acetamidophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429642-31-9C21H19N3O3S
- N-[(2,4-Dimethylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429643-83-4C21H20N2O2S
- Methyl 4-(3-(3-methoxy-2-naphthoyl)thioureido)benzoate330826-77-2C21H18N2O4S
- N-[(2-Hydroxy-4-methylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide364748-34-5C20H18N2O3S
- N-[(5-tert-Butyl-2-hydroxyphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide380307-38-0C23H24N2O3S
- 3-Methoxy-N-[(2-methylphenyl)carbamothioyl]naphthalene-2-carboxamide364743-32-8C20H18N2O2S
- Ethyl 4-({[(3-methoxynaphthalen-2-yl)carbonyl]carbamothioyl}amino)benzoate428859-46-5C22H20N2O4S
- 3-Methoxy-N-[(3-nitrophenyl)carbamothioyl]naphthalene-2-carboxamide428859-51-2C19H15N3O4S
- N-[(3-Chloro-4-methoxyphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide428860-67-7C20H17ClN2O3S
- N-[(2,3-Dichlorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide330829-07-7C19H14Cl2N2O2S
- N-[(3,4-Dimethylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429652-27-7C21H20N2O2S
- N-[(2-Chlorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429652-34-6C19H15ClN2O2S
- N-[(4-Bromophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide429653-64-5C19H15BrN2O2S
- N-[(4-Fluorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide330835-89-7C19H15FN2O2S
- N-[(3-Chloro-4-methylphenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide364747-01-3C20H17ClN2O2S
- 3-Methoxy-N-[(3-methylphenyl)carbamothioyl]naphthalene-2-carboxamide364616-29-5C20H18N2O2S
- N-[(3-Chlorophenyl)carbamothioyl]-3-methoxynaphthalene-2-carboxamide385390-23-8C19H15ClN2O2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CSc1nc(=O)n2ccccc2n1)Nc1ccccc115 chemicals
O=C(CCNc1ccccc1)c1ccc2ccccc2c115 chemicals
O=C(COc1ccccc1)Nc1ccc2c(c1)OCCO215 chemicals![Scaffold O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc1ccccc1](/scaffold/KDRIURZVJMYZNJ-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc1ccccc113 chemicals
O=C(CCc1ccccc1)Nc1ccc2ccccc2c113 chemicals![Scaffold O=C(NCCc1cc2ccccc2[nH]c1=O)c1ccccc1](/scaffold/RLWQKKJAXJDFAZ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1cc2ccccc2[nH]c1=O)c1ccccc112 chemicals
O=C(CCN1CCc2ccccc2C1)Nc1ccccc110 chemicals
O=C(CSc1ccc2ccccc2n1)Nc1ccccc18 chemicals
O=C(CSC1=NS(=O)(=O)c2ccccc2N1)Nc1ccccc18 chemicals
O=C(CCn1cnc2ccccc2c1=O)Nc1ccccc18 chemicals
O=C(NCCc1ccccc1)c1cc2ccccc2oc1=O7 chemicals
O=C(NCCc1ccccc1)c1cc(=O)c2ccccc2o17 chemicals