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Murcko scaffold

2,8-Diazaspiro(4.5)decan-3-one scaffold

51 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
51
With full pages
4
Scaffold SMILES

O=C1CC2(CCNCC2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,8-Diazaspiro(4.5)decan-3-one page
Murcko scaffold O=C1CC2(CCNCC2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

8-Methyl-2,8-diazaspiro(4.5)decan-3-one chemical structure, C9H16N2O, CAS 154495-67-7
8-Methyl-2,8-diazaspiro(4.5)decan-3-one
CAS 154495-67-7C9H16N2O
tert-Butyl 3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C13H22N2O3, CAS 169206-67-1
tert-Butyl 3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate
CAS 169206-67-1C13H22N2O3
8-Ethyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C10H18N2O, CAS 154495-68-8
8-Ethyl-2,8-diazaspiro[4.5]decan-3-one
CAS 154495-68-8C10H18N2O
2,8-Diazaspiro(4.5)decan-3-one chemical structure, C8H14N2O, CAS 561314-57-6
2,8-Diazaspiro(4.5)decan-3-one
CAS 561314-57-6C8H14N2O
2,8-Dimethyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C10H18N2O, CAS 757918-52-8
2,8-Dimethyl-2,8-diazaspiro[4.5]decan-3-one
CAS 757918-52-8C10H18N2O
(5R,7S)-7-Methyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C9H16N2O, CAS 1417789-40-2
(5R,7S)-7-Methyl-2,8-diazaspiro[4.5]decan-3-one
CAS 1417789-40-2C9H16N2O
2,8-Diazaspiro[4.5]decan-3-one 2,2,2-trifluoroacetate chemical structure, C10H15F3N2O3, CAS 1242339-85-0
2,8-Diazaspiro[4.5]decan-3-one 2,2,2-trifluoroacetate
CAS 1242339-85-0C10H15F3N2O3
2-Methyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C9H16N2O, CAS 1353506-68-9
2-Methyl-2,8-diazaspiro[4.5]decan-3-one
CAS 1353506-68-9C9H16N2O
2,8-Diazaspiro(4.5)decan-3-one hydrochloride chemical structure, C8H15ClN2O, CAS 945892-88-6
2,8-Diazaspiro(4.5)decan-3-one hydrochloride
CAS 945892-88-6C8H15ClN2O
8-(2-(Methylthio)acetyl)-2,8-diazaspiro[4.5]decan-3-one chemical structure, C11H18N2O2S, CAS 1483760-52-6
8-(2-(Methylthio)acetyl)-2,8-diazaspiro[4.5]decan-3-one
CAS 1483760-52-6C11H18N2O2S
8-(2-Methoxyacetyl)-2,8-diazaspiro[4.5]decan-3-one chemical structure, C11H18N2O3, CAS 1488748-15-7
8-(2-Methoxyacetyl)-2,8-diazaspiro[4.5]decan-3-one
CAS 1488748-15-7C11H18N2O3
2-Ethyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C10H18N2O, CAS 1380386-77-5
2-Ethyl-2,8-diazaspiro[4.5]decan-3-one
CAS 1380386-77-5C10H18N2O
2-Methyl-2,8-diazaspiro[4.5]decan-3-one hydrochloride chemical structure, C9H17ClN2O, CAS 1380300-72-0
2-Methyl-2,8-diazaspiro[4.5]decan-3-one hydrochloride
CAS 1380300-72-0C9H17ClN2O
2-Ethyl-2,8-diazaspiro[4.5]decan-3-one hydrochloride chemical structure, C10H19ClN2O, CAS 1380300-34-4
2-Ethyl-2,8-diazaspiro[4.5]decan-3-one hydrochloride
CAS 1380300-34-4C10H19ClN2O
2-(Propan-2-yl)-2,8-diazaspiro[4.5]decan-3-one hydrochloride chemical structure, C11H21ClN2O, CAS 1380300-45-7
2-(Propan-2-yl)-2,8-diazaspiro[4.5]decan-3-one hydrochloride
CAS 1380300-45-7C11H21ClN2O
2-Isopropyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C11H20N2O, CAS 1380386-81-1
2-Isopropyl-2,8-diazaspiro[4.5]decan-3-one
CAS 1380386-81-1C11H20N2O
8-tert-Butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate chemical structure, C16H26N2O5, CAS 1445951-68-7
8-tert-Butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate
CAS 1445951-68-7C16H26N2O5
4,4-Dimethyl-2,8-diazaspiro[4.5]decan-3-one chemical structure, C10H18N2O, CAS 1402148-93-9
4,4-Dimethyl-2,8-diazaspiro[4.5]decan-3-one
CAS 1402148-93-9C10H18N2O
Di-tert-butyl 4-allyl-3-oxo-2,8-diazaspiro[4.5]decane-2,8-dicarboxylate chemical structure, C21H34N2O5, CAS 1402148-88-2
Di-tert-butyl 4-allyl-3-oxo-2,8-diazaspiro[4.5]decane-2,8-dicarboxylate
CAS 1402148-88-2C21H34N2O5
Di-tert-butyl 4-methyl-3-oxo-2,8-diazaspiro[4.5]decane-2,8-dicarboxylate chemical structure, C19H32N2O5, CAS 1402148-87-1
Di-tert-butyl 4-methyl-3-oxo-2,8-diazaspiro[4.5]decane-2,8-dicarboxylate
CAS 1402148-87-1C19H32N2O5
tert-Butyl 4-ethyl-3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C15H26N2O3, CAS 1402149-00-1
tert-Butyl 4-ethyl-3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1402149-00-1C15H26N2O3
8-(tert-Butoxycarbonyl)-3-oxo-2,8-diazaspiro[4.5]decane-4-carboxylic acid chemical structure, C14H22N2O5, CAS 1160246-82-1
8-(tert-Butoxycarbonyl)-3-oxo-2,8-diazaspiro[4.5]decane-4-carboxylic acid
CAS 1160246-82-1C14H22N2O5
tert-Butyl 1-(hydroxymethyl)-3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C14H24N2O4, CAS 1357353-90-2
tert-Butyl 1-(hydroxymethyl)-3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1357353-90-2C14H24N2O4
2,8-Diazaspiro[4.5]decan-3-one dihydrochloride chemical structure, C8H16Cl2N2O, CAS 1417301-86-0
2,8-Diazaspiro[4.5]decan-3-one dihydrochloride
CAS 1417301-86-0C8H16Cl2N2O