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Murcko scaffold

Ring system with 3 rings and 12 atoms

56 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
56
With full pages
7
Scaffold SMILES

c1ccc2c(c1)CCCC21CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCCC21CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 56 of 56 chemicals

7'-Methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine chemical structure, C13H17N, CAS 2167762-80-1
7'-Methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine
CAS 2167762-80-1C13H17N
7'-Ethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine chemical structure, C14H19N, CAS 2167668-06-4
7'-Ethyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine
CAS 2167668-06-4C14H19N
5'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine chemical structure, C12H14ClN, CAS 2168437-55-4
5'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine
CAS 2168437-55-4C12H14ClN
7'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine chemical structure, C12H14ClN, CAS 2168088-68-2
7'-Chloro-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine
CAS 2168088-68-2C12H14ClN
7'-(Trifluoromethyl)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine chemical structure, C13H14F3N, CAS 2172523-60-1
7'-(Trifluoromethyl)-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine
CAS 2172523-60-1C13H14F3N
7'-Fluoro-5'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine chemical structure, C13H16FN, CAS 2167704-77-8
7'-Fluoro-5'-methyl-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-4'-amine
CAS 2167704-77-8C13H16FN
tert-Butyl N-({7'-bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-3-yl}methyl)carbamate chemical structure, C18H24BrNO2, CAS 2680712-55-2
tert-Butyl N-({7'-bromo-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-naphthalen]-3-yl}methyl)carbamate
CAS 2680712-55-2C18H24BrNO2
rel-(1R,2S)-3',4'-Dihydrospiro[cyclopropane-1,1'(2'H)-naphthalene]-2-carboxylic acid chemical structure, C13H14O2
rel-(1R,2S)-3',4'-Dihydrospiro[cyclopropane-1,1'(2'H)-naphthalene]-2-carboxylic acid
C13H14O2