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Murcko scaffold

Ring system with 3 rings and 20 atoms

53 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
53
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1snnc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1snnc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

N-(4-Chlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C15H10ClN3OS, CAS 477857-82-2
N-(4-Chlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 477857-82-2C15H10ClN3OS
N-(4-Bromophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C15H10BrN3OS, CAS 477857-83-3
N-(4-Bromophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 477857-83-3C15H10BrN3OS
N-(3,5-Dichlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C15H9Cl2N3OS, CAS 477857-84-4
N-(3,5-Dichlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 477857-84-4C15H9Cl2N3OS
N-(2,3-Dichlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C15H9Cl2N3OS, CAS 477857-85-5
N-(2,3-Dichlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 477857-85-5C15H9Cl2N3OS
4-Phenyl-N-[3-(trifluoromethyl)phenyl]-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H10F3N3OS, CAS 477857-86-6
4-Phenyl-N-[3-(trifluoromethyl)phenyl]-1,2,3-thiadiazole-5-carboxamide
CAS 477857-86-6C16H10F3N3OS
4-Phenyl-N-[4-(trifluoromethyl)phenyl]-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H10F3N3OS, CAS 477857-87-7
4-Phenyl-N-[4-(trifluoromethyl)phenyl]-1,2,3-thiadiazole-5-carboxamide
CAS 477857-87-7C16H10F3N3OS
Methyl 4-{[(4-phenyl-1,2,3-thiadiazol-5-yl)carbonyl]amino}benzenecarboxylate chemical structure, C17H13N3O3S, CAS 477857-88-8
Methyl 4-{[(4-phenyl-1,2,3-thiadiazol-5-yl)carbonyl]amino}benzenecarboxylate
CAS 477857-88-8C17H13N3O3S
N-(5-Chloro-2-hydroxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C15H10ClN3O2S, CAS 860649-81-6
N-(5-Chloro-2-hydroxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 860649-81-6C15H10ClN3O2S
N-(2-Fluorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H12FN3O2S, CAS 1190288-99-3
N-(2-Fluorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190288-99-3C16H12FN3O2S
N-(3,5-Dimethoxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C17H15N3O3S, CAS 1190265-74-7
N-(3,5-Dimethoxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 1190265-74-7C17H15N3O3S
N-(2-Fluorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C15H10FN3OS, CAS 1190255-52-7
N-(2-Fluorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 1190255-52-7C15H10FN3OS
N-(2,5-Dimethoxyphenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C18H17N3O4S, CAS 1190246-77-5
N-(2,5-Dimethoxyphenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190246-77-5C18H17N3O4S
N-(3-Chloro-4-methoxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H12ClN3O2S, CAS 1190247-54-1
N-(3-Chloro-4-methoxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 1190247-54-1C16H12ClN3O2S
4-(4-Methoxyphenyl)-N-[3-(methylsulfanyl)phenyl]-1,2,3-thiadiazole-5-carboxamide chemical structure, C17H15N3O2S2, CAS 1190260-74-2
4-(4-Methoxyphenyl)-N-[3-(methylsulfanyl)phenyl]-1,2,3-thiadiazole-5-carboxamide
CAS 1190260-74-2C17H15N3O2S2
N-(3,4-Dichlorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H11Cl2N3O2S, CAS 1190296-74-2
N-(3,4-Dichlorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190296-74-2C16H11Cl2N3O2S
N-(3-Chloro-4-fluorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H11ClFN3O2S, CAS 1190266-43-3
N-(3-Chloro-4-fluorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190266-43-3C16H11ClFN3O2S
4-(4-Methoxyphenyl)-N-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H13N3O2S, CAS 1190297-76-7
4-(4-Methoxyphenyl)-N-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 1190297-76-7C16H13N3O2S
4-(4-Methoxyphenyl)-N-(3,4,5-trifluorophenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H10F3N3O2S, CAS 1190260-23-1
4-(4-Methoxyphenyl)-N-(3,4,5-trifluorophenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190260-23-1C16H10F3N3O2S
N-(5-Chloro-2-methoxyphenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C17H14ClN3O3S, CAS 1190301-96-2
N-(5-Chloro-2-methoxyphenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190301-96-2C17H14ClN3O3S
N-(4-Fluorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H12FN3O2S, CAS 1190287-07-0
N-(4-Fluorophenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190287-07-0C16H12FN3O2S
N-(3-Acetylphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C17H13N3O2S, CAS 1190244-39-3
N-(3-Acetylphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 1190244-39-3C17H13N3O2S
N-(5-Chloro-2-methoxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide chemical structure, C16H12ClN3O2S, CAS 1190281-92-5
N-(5-Chloro-2-methoxyphenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide
CAS 1190281-92-5C16H12ClN3O2S
4-(4-Methoxyphenyl)-N-[4-(propan-2-yl)phenyl]-1,2,3-thiadiazole-5-carboxamide chemical structure, C19H19N3O2S, CAS 1190288-14-2
4-(4-Methoxyphenyl)-N-[4-(propan-2-yl)phenyl]-1,2,3-thiadiazole-5-carboxamide
CAS 1190288-14-2C19H19N3O2S
N-(3,4-Dimethoxyphenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide chemical structure, C18H17N3O4S, CAS 1190284-01-5
N-(3,4-Dimethoxyphenyl)-4-(4-methoxyphenyl)-1,2,3-thiadiazole-5-carboxamide
CAS 1190284-01-5C18H17N3O4S