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Murcko scaffold

Ring system with 2 rings and 19 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
6
With full pages
3
Scaffold SMILES

O=C(NCc1ccccc1)C(=O)NCC1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)C(=O)NCC1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-(Oxolan-2-ylmethyl)-N'-(1-phenylethyl)oxamide chemical structure, C15H20N2O3, CAS 371142-93-7
N-(Oxolan-2-ylmethyl)-N'-(1-phenylethyl)oxamide
CAS 371142-93-7C15H20N2O3
N'-[(2-Methoxyphenyl)methyl]-N-(oxolan-2-ylmethyl)oxamide chemical structure, C15H20N2O4, CAS 404370-19-0
N'-[(2-Methoxyphenyl)methyl]-N-(oxolan-2-ylmethyl)oxamide
CAS 404370-19-0C15H20N2O4
N'-[(2-Methylphenyl)methyl]-N-(oxolan-2-ylmethyl)oxamide chemical structure, C15H20N2O3, CAS 591212-06-5
N'-[(2-Methylphenyl)methyl]-N-(oxolan-2-ylmethyl)oxamide
CAS 591212-06-5C15H20N2O3
N1-(4-fluorobenzyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide chemical structure, C14H17FN2O3, CAS 702650-05-3
N1-(4-fluorobenzyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide
CAS 702650-05-3C14H17FN2O3
N1-(2-chlorobenzyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide chemical structure, C14H17ClN2O3, CAS 339088-60-7
N1-(2-chlorobenzyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide
CAS 339088-60-7C14H17ClN2O3
N-(Oxolan-2-ylmethyl)-N'-[(4-propan-2-ylphenyl)methyl]oxamide chemical structure, C17H24N2O3, CAS 592477-67-3
N-(Oxolan-2-ylmethyl)-N'-[(4-propan-2-ylphenyl)methyl]oxamide
CAS 592477-67-3C17H24N2O3