CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
4
With full pages
3
Scaffold SMILES

O=C(CSc1nnc(Cc2ccccc2)[nH]1)NC1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(Cc2ccccc2)[nH]1)NC1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

2-[(5-Benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-cyclohexylacetamide chemical structure, C18H24N4OS, CAS 626204-32-8
2-[(5-Benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-cyclohexylacetamide
CAS 626204-32-8C18H24N4OS
N-Cyclohexyl-2-[[5-[(4-methoxyphenyl)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]acetamide chemical structure, C19H26N4O2S, CAS 665016-81-9
N-Cyclohexyl-2-[[5-[(4-methoxyphenyl)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]acetamide
CAS 665016-81-9C19H26N4O2S
2-[[4-Amino-5-[(2-fluorophenyl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-cyclohexyl-N-methylacetamide chemical structure, C18H24FN5OS, CAS 735295-49-5
2-[[4-Amino-5-[(2-fluorophenyl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-cyclohexyl-N-methylacetamide
CAS 735295-49-5C18H24FN5OS
2-[[4-Amino-5-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(1-cyanocyclohexyl)acetamide chemical structure, C19H24N6O2S, CAS 877158-47-9
2-[[4-Amino-5-[(4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(1-cyanocyclohexyl)acetamide
CAS 877158-47-9C19H24N6O2S