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Murcko scaffold

Ring system with 3 rings and 25 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
19
With full pages
3
Scaffold SMILES

O=C(COc1ccccc1)Nc1ncc(S(=O)(=O)c2ccccc2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ncc(S(=O)(=O)c2ccccc2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-(2-Chlorophenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C17H12ClN3O6S2, CAS 301694-50-8
2-(2-Chlorophenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 301694-50-8C17H12ClN3O6S2
2-(3-Chlorophenoxy)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}acetamide chemical structure, C17H12ClN3O6S2, CAS 301694-52-0
2-(3-Chlorophenoxy)-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}acetamide
CAS 301694-52-0C17H12ClN3O6S2
2-(2,5-Dichlorophenoxy)-N-(5-((4-nitrophenyl)sulfonyl)-2-thiazolyl)acetamide chemical structure, C17H11Cl2N3O6S2, CAS 292053-44-2
2-(2,5-Dichlorophenoxy)-N-(5-((4-nitrophenyl)sulfonyl)-2-thiazolyl)acetamide
CAS 292053-44-2C17H11Cl2N3O6S2
2-(2-tert-Butyl-4-methylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C22H23N3O6S2, CAS 301694-54-2
2-(2-tert-Butyl-4-methylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 301694-54-2C22H23N3O6S2
2-(2-tert-Butylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C21H21N3O6S2, CAS 301694-56-4
2-(2-tert-Butylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 301694-56-4C21H21N3O6S2
2-(2-Methylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C18H15N3O6S2, CAS 301694-58-6
2-(2-Methylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 301694-58-6C18H15N3O6S2
N-[5-(4-Nitrophenyl)sulfonyl-1,3-thiazol-2-yl]-2-phenoxyacetamide chemical structure, C17H13N3O6S2, CAS 292053-06-6
N-[5-(4-Nitrophenyl)sulfonyl-1,3-thiazol-2-yl]-2-phenoxyacetamide
CAS 292053-06-6C17H13N3O6S2
2-(4-Chlorophenoxy)-N-[5-(4-nitrobenzene-1-sulfonyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H12ClN3O6S2, CAS 5750-18-5
2-(4-Chlorophenoxy)-N-[5-(4-nitrobenzene-1-sulfonyl)-1,3-thiazol-2-yl]acetamide
CAS 5750-18-5C17H12ClN3O6S2
2-(4-Bromophenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C17H12BrN3O6S2, CAS 292053-45-3
2-(4-Bromophenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 292053-45-3C17H12BrN3O6S2
2-(4-Methoxyphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C18H15N3O7S2, CAS 302548-30-7
2-(4-Methoxyphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 302548-30-7C18H15N3O7S2
2-(5-Methyl-2-propan-2-ylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C21H21N3O6S2, CAS 292053-46-4
2-(5-Methyl-2-propan-2-ylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 292053-46-4C21H21N3O6S2
2-(4-Ethylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C19H17N3O6S2, CAS 302548-31-8
2-(4-Ethylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 302548-31-8C19H17N3O6S2
2-(4-Chloro-3-methylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C18H14ClN3O6S2, CAS 302548-33-0
2-(4-Chloro-3-methylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 302548-33-0C18H14ClN3O6S2
2-(4-Chloro-3,5-dimethylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C19H16ClN3O6S2, CAS 302548-34-1
2-(4-Chloro-3,5-dimethylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 302548-34-1C19H16ClN3O6S2
N-[5-(4-Nitrophenyl)sulfonyl-1,3-thiazol-2-yl]-2-(4-propan-2-ylphenoxy)acetamide chemical structure, C20H19N3O6S2, CAS 5743-59-9
N-[5-(4-Nitrophenyl)sulfonyl-1,3-thiazol-2-yl]-2-(4-propan-2-ylphenoxy)acetamide
CAS 5743-59-9C20H19N3O6S2
2-(3,5-Dimethylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide chemical structure, C19H17N3O6S2, CAS 347913-51-3
2-(3,5-Dimethylphenoxy)-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]acetamide
CAS 347913-51-3C19H17N3O6S2
2-(4-Chlorophenoxy)-2-methyl-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]propanamide chemical structure, C19H16ClN3O6S2, CAS 599153-10-3
2-(4-Chlorophenoxy)-2-methyl-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]propanamide
CAS 599153-10-3C19H16ClN3O6S2
N-{5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}-2-phenoxypropanamide chemical structure, C18H15N3O6S2, CAS 349542-25-2
N-{5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}-2-phenoxypropanamide
CAS 349542-25-2C18H15N3O6S2
N-{5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}-2-phenoxybutanamide chemical structure, C19H17N3O6S2, CAS 600158-84-7
N-{5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}-2-phenoxybutanamide
CAS 600158-84-7C19H17N3O6S2