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Murcko scaffold

N-(5-Oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide scaffold

77 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
77
With full pages
16
Scaffold SMILES

O=C1CC(NS(=O)(=O)c2ccccc2)CN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(5-Oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide page
Murcko scaffold O=C1CC(NS(=O)(=O)c2ccccc2)CN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

N-(1-(4-Ethoxyphenyl)-5-oxopyrrolidin-3-yl)-2,5-difluorobenzenesulfonamide chemical structure, C18H18F2N2O4S, CAS 896312-77-9
N-(1-(4-Ethoxyphenyl)-5-oxopyrrolidin-3-yl)-2,5-difluorobenzenesulfonamide
CAS 896312-77-9C18H18F2N2O4S
N-(5-Oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide chemical structure, C16H16N2O3S, CAS 905683-17-2
N-(5-Oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide
CAS 905683-17-2C16H16N2O3S
4-Methoxy-3-methyl-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide chemical structure, C18H20N2O4S, CAS 905683-45-6
4-Methoxy-3-methyl-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide
CAS 905683-45-6C18H20N2O4S
2,5-Difluoro-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide chemical structure, C16H14F2N2O3S, CAS 905683-52-5
2,5-Difluoro-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide
CAS 905683-52-5C16H14F2N2O3S
4-Methoxy-3-methyl-N-(5-oxo-1-(p-tolyl)pyrrolidin-3-yl)benzenesulfonamide chemical structure, C19H22N2O4S, CAS 905683-84-3
4-Methoxy-3-methyl-N-(5-oxo-1-(p-tolyl)pyrrolidin-3-yl)benzenesulfonamide
CAS 905683-84-3C19H22N2O4S
N-(1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl)-4-methoxybenzenesulfonamide chemical structure, C19H22N2O4S, CAS 905684-44-8
N-(1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl)-4-methoxybenzenesulfonamide
CAS 905684-44-8C19H22N2O4S
4-Acetyl-N-(1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl)benzenesulfonamide chemical structure, C20H22N2O4S, CAS 905684-51-7
4-Acetyl-N-(1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl)benzenesulfonamide
CAS 905684-51-7C20H22N2O4S
N-(4-(N-(1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl)sulfamoyl)phenyl)acetamide chemical structure, C20H23N3O4S, CAS 905684-59-5
N-(4-(N-(1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl)sulfamoyl)phenyl)acetamide
CAS 905684-59-5C20H23N3O4S
N-[1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl]-4-methoxy-3-methylbenzene-1-sulfonamide chemical structure, C20H24N2O4S, CAS 905684-87-9
N-[1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl]-4-methoxy-3-methylbenzene-1-sulfonamide
CAS 905684-87-9C20H24N2O4S
2,5-Difluoro-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]benzene-1-sulfonamide chemical structure, C17H16F2N2O4S, CAS 905685-54-3
2,5-Difluoro-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]benzene-1-sulfonamide
CAS 905685-54-3C17H16F2N2O4S
2-Fluoro-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]benzene-1-sulfonamide chemical structure, C17H17FN2O4S, CAS 905685-62-3
2-Fluoro-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]benzene-1-sulfonamide
CAS 905685-62-3C17H17FN2O4S
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]benzenesulfonamide chemical structure, C16H15FN2O3S, CAS 905686-68-2
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]benzenesulfonamide
CAS 905686-68-2C16H15FN2O3S
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]-4-methylbenzene-1-sulfonamide chemical structure, C17H17FN2O3S, CAS 905686-76-2
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]-4-methylbenzene-1-sulfonamide
CAS 905686-76-2C17H17FN2O3S
N-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-4-nitrobenzenesulfonamide chemical structure, C16H14FN3O5S, CAS 905686-91-1
N-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)-4-nitrobenzenesulfonamide
CAS 905686-91-1C16H14FN3O5S
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]benzenesulfonamide chemical structure, C16H15FN2O3S, CAS 905687-14-1
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]benzenesulfonamide
CAS 905687-14-1C16H15FN2O3S
N-(1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl)-4-methoxybenzenesulfonamide chemical structure, C17H17FN2O4S, CAS 905687-27-6
N-(1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl)-4-methoxybenzenesulfonamide
CAS 905687-27-6C17H17FN2O4S
4-Acetyl-N-(1-(4-fluorophenyl)-5-oxopyrrolidin-3-yl)benzenesulfonamide chemical structure, C18H17FN2O4S, CAS 905687-33-4
4-Acetyl-N-(1-(4-fluorophenyl)-5-oxopyrrolidin-3-yl)benzenesulfonamide
CAS 905687-33-4C18H17FN2O4S
N-(1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl)-4-methoxybenzenesulfonamide chemical structure, C17H17ClN2O4S, CAS 905687-67-4
N-(1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl)-4-methoxybenzenesulfonamide
CAS 905687-67-4C17H17ClN2O4S
4-Acetyl-N-(1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl)benzenesulfonamide chemical structure, C18H17ClN2O4S, CAS 905687-74-3
4-Acetyl-N-(1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl)benzenesulfonamide
CAS 905687-74-3C18H17ClN2O4S
N-(1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C18H19ClN2O4S, CAS 905688-02-0
N-(1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl)-4-methoxy-3-methylbenzenesulfonamide
CAS 905688-02-0C18H19ClN2O4S
N-(1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl)-2-fluorobenzenesulfonamide chemical structure, C16H14ClFN2O3S, CAS 905688-09-7
N-(1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl)-2-fluorobenzenesulfonamide
CAS 905688-09-7C16H14ClFN2O3S
4-Methoxy-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide chemical structure, C17H18N2O4S, CAS 896306-70-0
4-Methoxy-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide
CAS 896306-70-0C17H18N2O4S
3,4-Dimethoxy-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide chemical structure, C18H20N2O5S, CAS 896307-22-5
3,4-Dimethoxy-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide
CAS 896307-22-5C18H20N2O5S
2,5-Dimethoxy-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide chemical structure, C18H20N2O5S, CAS 896307-30-5
2,5-Dimethoxy-N-(5-oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide
CAS 896307-30-5C18H20N2O5S