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Murcko scaffold

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole scaffold

272 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
272
With full pages
23
Scaffold SMILES

c1n[nH]c2c1CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole page
Murcko scaffold c1n[nH]c2c1CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 272 chemicals

tert-Butyl 1-(2-amino-2-oxoethyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate chemical structure, C12H18N4O3, CAS 1270029-91-8
tert-Butyl 1-(2-amino-2-oxoethyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate
CAS 1270029-91-8C12H18N4O3
1-(5,6-Dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)-2-methylpropan-2-ol chemical structure, C9H15N3O, CAS 1270029-94-1
1-(5,6-Dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)-2-methylpropan-2-ol
CAS 1270029-94-1C9H15N3O
tert-Butyl 2-(2-amino-2-oxoethyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate chemical structure, C12H18N4O3, CAS 1270029-90-7
tert-Butyl 2-(2-amino-2-oxoethyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
CAS 1270029-90-7C12H18N4O3
Methyl 2-(5,6-dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)acetate chemical structure, C8H11N3O2, CAS 1329996-84-0
Methyl 2-(5,6-dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)acetate
CAS 1329996-84-0C8H11N3O2
tert-Butyl 2-(Methylsulfonyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate chemical structure, C11H17N3O4S, CAS 1226781-82-3
tert-Butyl 2-(Methylsulfonyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
CAS 1226781-82-3C11H17N3O4S
3-Hydroxymethyl-4,6-dihydro-1H-pyrrolo[3,4-C]pyrazole-5-carboxylic acid tert-butyl ester chemical structure, C11H17N3O3, CAS 1251014-83-1
3-Hydroxymethyl-4,6-dihydro-1H-pyrrolo[3,4-C]pyrazole-5-carboxylic acid tert-butyl ester
CAS 1251014-83-1C11H17N3O3
tert-Butyl 3-(aminomethyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate chemical structure, C11H18N4O2, CAS 1251002-81-9
tert-Butyl 3-(aminomethyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate
CAS 1251002-81-9C11H18N4O2
5-Ethyl-2-methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine chemical structure, C8H14N4, CAS 1420994-43-9
5-Ethyl-2-methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine
CAS 1420994-43-9C8H14N4
2,5-Dimethyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine chemical structure, C7H12N4, CAS 1420850-11-8
2,5-Dimethyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine
CAS 1420850-11-8C7H12N4
tert-Butyl 3-amino-2-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate chemical structure, C11H18N4O2, CAS 1244772-00-6
tert-Butyl 3-amino-2-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
CAS 1244772-00-6C11H18N4O2
2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine chemical structure, C6H10N4, CAS 1251822-66-8
2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-amine
CAS 1251822-66-8C6H10N4
tert-Butyl 1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate chemical structure, C11H17N3O2, CAS 1268520-16-6
tert-Butyl 1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate
CAS 1268520-16-6C11H17N3O2
5-Boc-3-methyl-4,6-dihydro-1H-pyrrolo[3,4-C]pyrazole chemical structure, C11H17N3O2, CAS 951127-35-8
5-Boc-3-methyl-4,6-dihydro-1H-pyrrolo[3,4-C]pyrazole
CAS 951127-35-8C11H17N3O2
tert-Butyl 3-amino-6-methyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(1H)-carboxylate chemical structure, C11H18N4O2, CAS 1196155-05-1
tert-Butyl 3-amino-6-methyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(1H)-carboxylate
CAS 1196155-05-1C11H18N4O2
tert-Butyl 3-amino-6-tert-butyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(1H)-carboxylate chemical structure, C14H24N4O2, CAS 1196152-07-4
tert-Butyl 3-amino-6-tert-butyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(1H)-carboxylate
CAS 1196152-07-4C14H24N4O2
tert-Butyl 3-bromo-1-methyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(1H)-carboxylate chemical structure, C11H16BrN3O2, CAS 1393539-88-2
tert-Butyl 3-bromo-1-methyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(1H)-carboxylate
CAS 1393539-88-2C11H16BrN3O2
3-Methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole hydrochloride chemical structure, C6H10ClN3, CAS 1389264-31-6
3-Methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole hydrochloride
CAS 1389264-31-6C6H10ClN3
1,4,5,6-Tetrahydro-1-methyl-3-(trifluoromethyl)pyrrolo-[3,4-c]-pyrazole hydrochloride chemical structure, C7H9ClF3N3, CAS 1190972-66-7
1,4,5,6-Tetrahydro-1-methyl-3-(trifluoromethyl)pyrrolo-[3,4-c]-pyrazole hydrochloride
CAS 1190972-66-7C7H9ClF3N3
2-(5,6-Dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)ethanol chemical structure, C7H11N3O, CAS 1329996-83-9
2-(5,6-Dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)ethanol
CAS 1329996-83-9C7H11N3O
5-[(tert-Butoxy)carbonyl]-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C12H17N3O4, CAS 2309456-25-3
5-[(tert-Butoxy)carbonyl]-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2309456-25-3C12H17N3O4
2,4,5,6-Tetrahydro-pyrrolo[3,4-c]pyrazole-3-methanamine chemical structure, C6H10N4, CAS 1547100-41-3
2,4,5,6-Tetrahydro-pyrrolo[3,4-c]pyrazole-3-methanamine
CAS 1547100-41-3C6H10N4
5-Methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-amine chemical structure, C6H10N4, CAS 1367946-28-8
5-Methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-amine
CAS 1367946-28-8C6H10N4
2-Ethyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole chemical structure, C7H11N3, CAS 1369368-90-0
2-Ethyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole
CAS 1369368-90-0C7H11N3
2,4-Dimethyl-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazole chemical structure, C7H11N3, CAS 1367938-51-9
2,4-Dimethyl-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazole
CAS 1367938-51-9C7H11N3