Murcko scaffold
Ring system with 2 rings and 9 atoms
35 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 35
- With full pages
- 8
Scaffold SMILES
C1CC2(C1)COCCO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 35 of 35 chemicals
![5,8-Dioxaspiro[3.5]nonan-6-ylmethanesulfonyl chloride chemical structure, C8H13ClO4S, CAS 2168493-47-6](/s/HMONXRHKVBJXMX-UHFFFAOYSA-N.svg)
5,8-Dioxaspiro[3.5]nonan-6-ylmethanesulfonyl chloride
CAS 2168493-47-6C8H13ClO4S
![6-(Iodomethyl)-5,8-dioxaspiro[3.5]nonane chemical structure, C8H13IO2, CAS 2169583-65-5](/s/OWWHNZBFHMSESO-UHFFFAOYSA-N.svg)
6-(Iodomethyl)-5,8-dioxaspiro[3.5]nonane
CAS 2169583-65-5C8H13IO2
![{5,8-Dioxaspiro[3.5]nonan-9-yl}methanol chemical structure, C8H14O3, CAS 2470440-47-0](/s/UEEMEZVHQXFUJI-UHFFFAOYSA-N.svg)
{5,8-Dioxaspiro[3.5]nonan-9-yl}methanol
CAS 2470440-47-0C8H14O3
![5,8-Dioxaspiro[3.5]nonane-9-carboxylic acid chemical structure, C8H12O4, CAS 2383600-74-4](/s/TYYFPTCTXCDHAI-UHFFFAOYSA-N.svg)
5,8-Dioxaspiro[3.5]nonane-9-carboxylic acid
CAS 2383600-74-4C8H12O4
(5,8-Dioxaspiro(3.5)nonan-6-yl)methanol
CAS 2169090-39-3C8H14O3
![5,8-Dioxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C8H12O4, CAS 2167952-49-8](/s/ZMSREWUVHJJPMN-UHFFFAOYSA-N.svg)
5,8-Dioxaspiro[3.5]nonane-2-carboxylic acid
CAS 2167952-49-8C8H12O4
![1-{5,8-Dioxaspiro[3.5]nonan-6-yl}methanamine hydrochloride chemical structure, C8H16ClNO2, CAS 2243515-58-2](/s/WQAWSEFYVXVTOA-UHFFFAOYSA-N.svg)
1-{5,8-Dioxaspiro[3.5]nonan-6-yl}methanamine hydrochloride
CAS 2243515-58-2C8H16ClNO2
![1-{5,8-Dioxaspiro[3.5]nonan-6-yl}methanamine chemical structure, C8H15NO2, CAS 2167506-93-4](/s/VOUFPXXKTUTDQD-UHFFFAOYSA-N.svg)
1-{5,8-Dioxaspiro[3.5]nonan-6-yl}methanamine
CAS 2167506-93-4C8H15NO2
![5,8-Dioxaspiro[3.5]nonane-6-carboxylic acid chemical structure, C8H12O4, CAS 2386539-47-3](/s/PHRVDZLFNMPDEO-UHFFFAOYSA-N.svg)
5,8-Dioxaspiro[3.5]nonane-6-carboxylic acid
CAS 2386539-47-3C8H12O4
![2-{5,8-Dioxaspiro[3.5]nonan-6-yl}ethan-1-amine chemical structure, C9H17NO2, CAS 2648947-63-9](/s/NLMNVFLWSBKMSQ-UHFFFAOYSA-N.svg)
2-{5,8-Dioxaspiro[3.5]nonan-6-yl}ethan-1-amine
CAS 2648947-63-9C9H17NO2
![2-{5,8-Dioxaspiro[3.5]nonan-7-yl}ethan-1-amine hydrochloride chemical structure, C9H18ClNO2, CAS 2648945-75-7](/s/OIXKGCCYSAZAJH-UHFFFAOYSA-N.svg)
2-{5,8-Dioxaspiro[3.5]nonan-7-yl}ethan-1-amine hydrochloride
CAS 2648945-75-7C9H18ClNO2
![2-{5,8-Dioxaspiro[3.5]nonan-7-yl}ethan-1-amine chemical structure, C9H17NO2, CAS 2648945-74-6](/s/HJUBFJLWWBCDLG-UHFFFAOYSA-N.svg)
2-{5,8-Dioxaspiro[3.5]nonan-7-yl}ethan-1-amine
CAS 2648945-74-6C9H17NO2
![1-{5,8-Dioxaspiro[3.5]nonan-2-yl}methanamine hydrochloride chemical structure, C8H16ClNO2, CAS 2648960-95-4](/s/RQGAIEJNUNXRIQ-UHFFFAOYSA-N.svg)
1-{5,8-Dioxaspiro[3.5]nonan-2-yl}methanamine hydrochloride
CAS 2648960-95-4C8H16ClNO2
![1-{5,8-Dioxaspiro[3.5]nonan-2-yl}methanamine chemical structure, C8H15NO2, CAS 2648960-94-3](/s/YIBDSKLYHMQWNK-UHFFFAOYSA-N.svg)
1-{5,8-Dioxaspiro[3.5]nonan-2-yl}methanamine
CAS 2648960-94-3C8H15NO2
![1-{5,8-Dioxaspiro[3.5]nonan-7-yl}methanamine hydrochloride chemical structure, C8H16ClNO2, CAS 2624138-86-7](/s/LWSJOVRNHKEHAZ-UHFFFAOYSA-N.svg)
1-{5,8-Dioxaspiro[3.5]nonan-7-yl}methanamine hydrochloride
CAS 2624138-86-7C8H16ClNO2
![1-{5,8-Dioxaspiro[3.5]nonan-7-yl}methanamine chemical structure, C8H15NO2, CAS 2624134-68-3](/s/PILRYGAQGTWFQW-UHFFFAOYSA-N.svg)
1-{5,8-Dioxaspiro[3.5]nonan-7-yl}methanamine
CAS 2624134-68-3C8H15NO2
![2-{5,8-Dioxaspiro[3.5]nonan-7-yl}acetic acid chemical structure, C9H14O4, CAS 2624140-21-0](/s/BVSPDOWLWRZPLD-UHFFFAOYSA-N.svg)
2-{5,8-Dioxaspiro[3.5]nonan-7-yl}acetic acid
CAS 2624140-21-0C9H14O4
![5,8-Dioxaspiro[3.5]nonane-7-carboxylic acid chemical structure, C8H12O4, CAS 2624131-84-4](/s/GJGDEAIOFOCEPA-UHFFFAOYSA-N.svg)
5,8-Dioxaspiro[3.5]nonane-7-carboxylic acid
CAS 2624131-84-4C8H12O4
(5,8-Dioxaspiro(3.5)nonan-7-yl)methanesulfonyl chloride
CAS 2624140-88-9C8H13ClO4S
![{5,8-Dioxaspiro[3.5]nonan-7-yl}methanol chemical structure, C8H14O3, CAS 2624142-08-9](/s/SNLNDTANJNMANL-UHFFFAOYSA-N.svg)
{5,8-Dioxaspiro[3.5]nonan-7-yl}methanol
CAS 2624142-08-9C8H14O3
![6-(Bromomethyl)-5,8-dioxaspiro[3.5]nonane chemical structure, C8H13BrO2, CAS 2169153-05-1](/s/AVOQXGNZLGJFCQ-UHFFFAOYSA-N.svg)
6-(Bromomethyl)-5,8-dioxaspiro[3.5]nonane
CAS 2169153-05-1C8H13BrO2
![6-(Azidomethyl)-5,8-dioxaspiro[3.5]nonane chemical structure, C8H13N3O2, CAS 2172002-31-0](/s/LFCIIDJOURTRHF-UHFFFAOYSA-N.svg)
6-(Azidomethyl)-5,8-dioxaspiro[3.5]nonane
CAS 2172002-31-0C8H13N3O2
![{5,8-Dioxaspiro[3.5]nonan-6-yl}methanesulfonamide chemical structure, C8H15NO4S, CAS 2168090-40-0](/s/ANQMWHIOIZNNEH-UHFFFAOYSA-N.svg)
{5,8-Dioxaspiro[3.5]nonan-6-yl}methanesulfonamide
CAS 2168090-40-0C8H15NO4S
![{5,8-Dioxaspiro[3.5]nonan-6-yl}methanesulfonyl fluoride chemical structure, C8H13FO4S, CAS 2168797-75-7](/s/DNHCJAPLIVLBBF-UHFFFAOYSA-N.svg)
{5,8-Dioxaspiro[3.5]nonan-6-yl}methanesulfonyl fluoride
CAS 2168797-75-7C8H13FO4S
- 2-(5,8-Dioxaspiro(3.5)nonan-6-yl)acetic acid2167817-13-0C9H14O4
- 9-(Azidomethyl)-5,8-dioxaspiro[3.5]nonane2757999-75-8C8H13N3O2
- 1-{5,8-Dioxaspiro[3.5]nonan-9-yl}methanamine hydrochloride2757999-63-4C8H16ClNO2
- 1-{5,8-Dioxaspiro[3.5]nonan-9-yl}methanamine2757891-67-9C8H15NO2
- {5,8-Dioxaspiro[3.5]nonan-7-yl}methanesulfonyl fluoride2648947-56-0C8H13FO4S
- {5,8-Dioxaspiro[3.5]nonan-7-yl}methanesulfonamide2639446-06-1C8H15NO4S
- 5,8-Dioxaspiro[3.5]nonan-2-amine hydrochloride2680530-54-3C7H14ClNO2
- 5,8-Dioxaspiro[3.5]nonan-2-amine2680530-53-2C7H13NO2
- 2-(Bromomethyl)-5,8-dioxaspiro[3.5]nonane2680543-11-5C8H13BrO2
- 1-{6-Methyl-5,8-dioxaspiro[3.5]nonan-6-yl}methanamine2703773-43-5C9H17NO2
- 9-(Bromomethyl)-5,8-dioxaspiro[3.5]nonane2758001-83-9C8H13BrO2
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2(C1)CCNCC241 chemicals
C1CCC2(CC1)CCC238 chemicals
C1CC2(C1)CCOCC229 chemicals
C1CNCC2(C1)CCC228 chemicals
C1CCC2(CCC2)OC126 chemicals
C1CC2(C1)CNCCO219 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CC1)CNC214 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals