CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
16
With full pages
6
Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)o1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccccc2)o1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Ethyl 4-(2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate chemical structure, C17H20N4O4S, CAS 850936-65-1
Ethyl 4-(2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate
CAS 850936-65-1C17H20N4O4S
Ethyl 4-(2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate chemical structure, C18H22N4O4S, CAS 850936-68-4
Ethyl 4-(2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate
CAS 850936-68-4C18H22N4O4S
Ethyl 4-(2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate chemical structure, C18H22N4O4S, CAS 850936-74-2
Ethyl 4-(2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate
CAS 850936-74-2C18H22N4O4S
Ethyl 4-(2-((5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate chemical structure, C18H22N4O4S, CAS 850936-79-7
Ethyl 4-(2-((5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate
CAS 850936-79-7C18H22N4O4S
Ethyl 4-(2-{[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C17H19FN4O4S, CAS 850937-00-7
Ethyl 4-(2-{[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 850937-00-7C17H19FN4O4S
Ethyl 4-(2-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C17H19ClN4O4S, CAS 850937-02-9
Ethyl 4-(2-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 850937-02-9C17H19ClN4O4S
Ethyl 4-(2-{[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C17H19FN4O4S, CAS 850937-06-3
Ethyl 4-(2-{[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 850937-06-3C17H19FN4O4S
Ethyl 4-(2-{[5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C19H24N4O5S, CAS 850937-17-6
Ethyl 4-(2-{[5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 850937-17-6C19H24N4O5S
Ethyl 4-(2-((5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate chemical structure, C17H19ClN4O4S, CAS 850937-58-5
Ethyl 4-(2-((5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate
CAS 850937-58-5C17H19ClN4O4S
Ethyl 4-(2-{[5-(3,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C19H24N4O4S, CAS 851129-41-4
Ethyl 4-(2-{[5-(3,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 851129-41-4C19H24N4O4S
Ethyl 4-({[5-(2,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)piperazine-1-carboxylate chemical structure, C19H24N4O6S, CAS 851129-67-4
Ethyl 4-({[5-(2,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)piperazine-1-carboxylate
CAS 851129-67-4C19H24N4O6S
Ethyl 4-(2-{[5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C19H24N4O6S, CAS 851129-27-6
Ethyl 4-(2-{[5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 851129-27-6C19H24N4O6S
Ethyl 4-({[5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)piperazine-1-carboxylate chemical structure, C18H22N4O5S, CAS 850936-95-7
Ethyl 4-({[5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)piperazine-1-carboxylate
CAS 850936-95-7C18H22N4O5S
Ethyl 4-(2-{[5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C19H24N4O6S, CAS 850937-28-9
Ethyl 4-(2-{[5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 850937-28-9C19H24N4O6S
Ethyl 4-(2-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C18H22N4O5S, CAS 850936-82-2
Ethyl 4-(2-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 850936-82-2C18H22N4O5S
Ethyl 4-(2-{[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate chemical structure, C21H28N4O4S, CAS 851129-23-2
Ethyl 4-(2-{[5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetyl)piperazine-1-carboxylate
CAS 851129-23-2C21H28N4O4S