CompoundList
Sign in
Murcko scaffold

Spiro(4.5)decan-8-one scaffold

72 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
72
With full pages
2
Scaffold SMILES

O=C1CCC2(CCCC2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Spiro(4.5)decan-8-one page
Murcko scaffold O=C1CCC2(CCCC2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

6-Methylspiro[4.5]decan-8-one chemical structure, C11H18O, CAS 143768-51-8
6-Methylspiro[4.5]decan-8-one
CAS 143768-51-8C11H18O
6,10-Dimethylspiro[4.5]decan-8-one chemical structure, C12H20O, CAS 88245-92-5
6,10-Dimethylspiro[4.5]decan-8-one
CAS 88245-92-5C12H20O
7,9-Dibromo-6,10-dimethylspiro[4.5]decan-8-one chemical structure, C12H18Br2O, CAS 88245-93-6
7,9-Dibromo-6,10-dimethylspiro[4.5]decan-8-one
CAS 88245-93-6C12H18Br2O
Spiro(4.5)decan-8-one chemical structure, C10H16O, CAS 4027-35-4
Spiro(4.5)decan-8-one
CAS 4027-35-4C10H16O
Isolubimin chemical structure, C15H24O2, CAS 60077-68-1
Isolubimin
CAS 60077-68-1C15H24O2
8-Oxospiro[4.5]decane-7-carbonitrile chemical structure, C11H15NO, CAS 1428757-75-8
8-Oxospiro[4.5]decane-7-carbonitrile
CAS 1428757-75-8C11H15NO
7-Aminospiro[4.5]decan-8-one chemical structure, C10H17NO, CAS 1599848-47-1
7-Aminospiro[4.5]decan-8-one
CAS 1599848-47-1C10H17NO
7-(Aminomethyl)spiro[4.5]decan-8-one chemical structure, C11H19NO, CAS 1823905-45-8
7-(Aminomethyl)spiro[4.5]decan-8-one
CAS 1823905-45-8C11H19NO
Methyl 8-oxospiro[4.5]decane-7-carboxylate chemical structure, C12H18O3, CAS 1602937-10-9
Methyl 8-oxospiro[4.5]decane-7-carboxylate
CAS 1602937-10-9C12H18O3
Ethyl 2-oxo-2-(8-oxospiro[4.5]decan-7-yl)acetate chemical structure, C14H20O4, CAS 1711045-28-1
Ethyl 2-oxo-2-(8-oxospiro[4.5]decan-7-yl)acetate
CAS 1711045-28-1C14H20O4
7-Propanoylspiro[4.5]decan-8-one chemical structure, C13H20O2, CAS 1594104-49-0
7-Propanoylspiro[4.5]decan-8-one
CAS 1594104-49-0C13H20O2
8-Oxospiro[4.5]decane-7-carbaldehyde chemical structure, C11H16O2, CAS 1594785-69-9
8-Oxospiro[4.5]decane-7-carbaldehyde
CAS 1594785-69-9C11H16O2
7-Acetylspiro[4.5]decan-8-one chemical structure, C12H18O2, CAS 1594466-13-3
7-Acetylspiro[4.5]decan-8-one
CAS 1594466-13-3C12H18O2
2-Methylspiro[4.5]decan-8-one chemical structure, C11H18O, CAS 2269476-42-6
2-Methylspiro[4.5]decan-8-one
CAS 2269476-42-6C11H18O
6-Hydroxyspiro[4.5]decan-8-one chemical structure, C10H16O2, CAS 2138534-73-1
6-Hydroxyspiro[4.5]decan-8-one
CAS 2138534-73-1C10H16O2
1-Methylspiro[4.5]decan-8-one chemical structure, C11H18O, CAS 2269476-41-5
1-Methylspiro[4.5]decan-8-one
CAS 2269476-41-5C11H18O
6-(But-3-yn-1-yl)spiro[4.5]decan-8-one chemical structure, C14H20O, CAS 2138527-87-2
6-(But-3-yn-1-yl)spiro[4.5]decan-8-one
CAS 2138527-87-2C14H20O
6-(But-2-yn-1-yl)spiro[4.5]decan-8-one chemical structure, C14H20O, CAS 2138116-01-3
6-(But-2-yn-1-yl)spiro[4.5]decan-8-one
CAS 2138116-01-3C14H20O
6-(Ethoxymethyl)spiro[4.5]decan-8-one chemical structure, C13H22O2, CAS 2138034-86-1
6-(Ethoxymethyl)spiro[4.5]decan-8-one
CAS 2138034-86-1C13H22O2
6-Ethylspiro[4.5]decan-8-one chemical structure, C12H20O, CAS 2138103-04-3
6-Ethylspiro[4.5]decan-8-one
CAS 2138103-04-3C12H20O
6-(3-Hydroxypropyl)spiro[4.5]decan-8-one chemical structure, C13H22O2, CAS 2138560-07-1
6-(3-Hydroxypropyl)spiro[4.5]decan-8-one
CAS 2138560-07-1C13H22O2
2-{8-Oxospiro[4.5]decan-6-yl}acetic acid chemical structure, C12H18O3, CAS 2138034-89-4
2-{8-Oxospiro[4.5]decan-6-yl}acetic acid
CAS 2138034-89-4C12H18O3
6-[(Methylamino)methyl]spiro[4.5]decan-8-one chemical structure, C12H21NO, CAS 2138088-83-0
6-[(Methylamino)methyl]spiro[4.5]decan-8-one
CAS 2138088-83-0C12H21NO
6-(2-Methoxyethyl)spiro[4.5]decan-8-one chemical structure, C13H22O2, CAS 2138103-12-3
6-(2-Methoxyethyl)spiro[4.5]decan-8-one
CAS 2138103-12-3C13H22O2