Murcko scaffold
Ring system with 3 rings and 21 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 21
- Chemicals
- 6
- With full pages
- 3
Scaffold SMILES
O=C(Nc1ccccc1)Nc1csc(-c2ccccc2)c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
Ethyl 3-[(4-ethoxycarbonylphenyl)carbamoylamino]-5-phenylthiophene-2-carboxylate
CAS 391866-79-8C23H22N2O5S
Methyl 3-(3-(4-nitrophenyl)ureido)-5-phenylthiophene-2-carboxylate
CAS 477326-73-1C19H15N3O5S
Ethyl 5-phenyl-3-(phenylcarbamoylamino)thiophene-2-carboxylate
CAS 391867-59-7C20H18N2O3S
Ethyl 3-[(4-methoxyphenyl)carbamoylamino]-5-phenylthiophene-2-carboxylate
CAS 391866-81-2C21H20N2O4S
Ethyl 3-(3-(4-nitrophenyl)ureido)-5-phenylthiophene-2-carboxylate
CAS 391868-20-5C20H17N3O5S
Methyl 3-[(4-ethoxyphenyl)carbamoylamino]-5-phenylthiophene-2-carboxylate
CAS 477326-74-2C21H20N2O4S