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Murcko scaffold

Ring system with 3 rings and 19 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
21
With full pages
2
Scaffold SMILES

O=C(c1ccccc1)N1CCC(c2ccccc2)=N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCC(c2ccccc2)=N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

[5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](4-methoxyphenyl)methanone chemical structure, C18H15F3N2O3, CAS 376612-06-5
[5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](4-methoxyphenyl)methanone
CAS 376612-06-5C18H15F3N2O3
(4-Chlorophenyl)-[3-(4-chlorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C17H11Cl2F3N2O2, CAS 372086-33-4
(4-Chlorophenyl)-[3-(4-chlorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 372086-33-4C17H11Cl2F3N2O2
[5-Hydroxy-3-(4-nitrophenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]-phenylmethanone chemical structure, C17H12F3N3O4, CAS 352349-93-0
[5-Hydroxy-3-(4-nitrophenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]-phenylmethanone
CAS 352349-93-0C17H12F3N3O4
AC1Mepnb chemical structure, C17H13F3N2O2, CAS 5660-33-3
AC1Mepnb
CAS 5660-33-3C17H13F3N2O2
[3-(4-Bromophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methoxyphenyl)methanone chemical structure, C18H14BrF3N2O3, CAS 375350-31-5
[3-(4-Bromophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methoxyphenyl)methanone
CAS 375350-31-5C18H14BrF3N2O3
[5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-nitrophenyl)methanone chemical structure, C17H12F3N3O4, CAS 5795-34-6
[5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-nitrophenyl)methanone
CAS 5795-34-6C17H12F3N3O4
(2-Hydroxy-3-methylphenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C18H15F3N2O3, CAS 364620-06-4
(2-Hydroxy-3-methylphenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 364620-06-4C18H15F3N2O3
(4-Bromophenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C17H12BrF3N2O2, CAS 376601-84-2
(4-Bromophenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 376601-84-2C17H12BrF3N2O2
[5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(4-iodophenyl)methanone chemical structure, C17H12F3IN2O2, CAS 376621-81-7
[5-Hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(4-iodophenyl)methanone
CAS 376621-81-7C17H12F3IN2O2
(2-Chlorophenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C17H12ClF3N2O2, CAS 352349-92-9
(2-Chlorophenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 352349-92-9C17H12ClF3N2O2
[3-(4-Bromophenyl)-5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](4-methoxyphenyl)methanone chemical structure, C18H14BrF3N2O3, CAS 376605-67-3
[3-(4-Bromophenyl)-5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](4-methoxyphenyl)methanone
CAS 376605-67-3C18H14BrF3N2O3
[3-(4-Bromophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methylphenyl)methanone chemical structure, C18H14BrF3N2O2, CAS 352649-04-8
[3-(4-Bromophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methylphenyl)methanone
CAS 352649-04-8C18H14BrF3N2O2
(4-tert-Butylphenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C21H21F3N2O2, CAS 420816-35-9
(4-tert-Butylphenyl)-[5-hydroxy-3-phenyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 420816-35-9C21H21F3N2O2
(4-Chlorophenyl)-[5-hydroxy-3-(4-nitrophenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C17H11ClF3N3O4, CAS 352349-91-8
(4-Chlorophenyl)-[5-hydroxy-3-(4-nitrophenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 352349-91-8C17H11ClF3N3O4
(4-Chlorophenyl)-[3-(4-fluorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone chemical structure, C17H11ClF4N2O2, CAS 376605-52-6
(4-Chlorophenyl)-[3-(4-fluorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanone
CAS 376605-52-6C17H11ClF4N2O2
[3-(4-Fluorophenyl)-5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](4-methoxyphenyl)methanone chemical structure, C18H14F4N2O3, CAS 364616-15-9
[3-(4-Fluorophenyl)-5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl](4-methoxyphenyl)methanone
CAS 364616-15-9C18H14F4N2O3
[3-(4-Chlorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(2-hydroxyphenyl)methanone chemical structure, C17H12ClF3N2O3, CAS 352346-56-6
[3-(4-Chlorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(2-hydroxyphenyl)methanone
CAS 352346-56-6C17H12ClF3N2O3
[3-(4-Chlorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3,4-dimethoxyphenyl)methanone chemical structure, C19H16ClF3N2O4, CAS 443295-91-8
[3-(4-Chlorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3,4-dimethoxyphenyl)methanone
CAS 443295-91-8C19H16ClF3N2O4
1-Benzoyl-3-(3-bromophenyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol chemical structure, C17H12BrF3N2O2, CAS 352349-85-0
1-Benzoyl-3-(3-bromophenyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol
CAS 352349-85-0C17H12BrF3N2O2
[3-(4-Fluorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methoxyphenyl)methanone chemical structure, C18H14F4N2O3, CAS 364741-82-2
[3-(4-Fluorophenyl)-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methoxyphenyl)methanone
CAS 364741-82-2C18H14F4N2O3
1-(4-Methylbenzoyl)-3-phenyl-4,5-dihydro-1H-pyrazole chemical structure, C17H16N2O, CAS 1421323-58-1
1-(4-Methylbenzoyl)-3-phenyl-4,5-dihydro-1H-pyrazole
CAS 1421323-58-1C17H16N2O