CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

33 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
33
With full pages
3
Scaffold SMILES

c1ccc(C2Nc3ccccc3C(c3ccccc3)N2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2Nc3ccccc3C(c3ccccc3)N2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

Ethyl 2-[6-bromo-2-(2-methoxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C25H25BrN2O3, CAS 5861-51-8
Ethyl 2-[6-bromo-2-(2-methoxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 5861-51-8C25H25BrN2O3
[6-Bromo-2-(4-methoxyphenyl)-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl]acetic acid chemical structure, C23H21BrN2O3, CAS 330850-63-0
[6-Bromo-2-(4-methoxyphenyl)-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl]acetic acid
CAS 330850-63-0C23H21BrN2O3
Methyl 2-[6-bromo-2-(4-methoxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C24H23BrN2O3, CAS 5868-31-5
Methyl 2-[6-bromo-2-(4-methoxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 5868-31-5C24H23BrN2O3
Methyl [6-methyl-4-phenyl-2-(3,4,5-trimethoxyphenyl)-1,4-dihydroquinazolin-3(2H)-yl]acetate chemical structure, C27H30N2O5, CAS 330850-71-0
Methyl [6-methyl-4-phenyl-2-(3,4,5-trimethoxyphenyl)-1,4-dihydroquinazolin-3(2H)-yl]acetate
CAS 330850-71-0C27H30N2O5
[6-Bromo-2-(2-hydroxy-phenyl)-4-phenyl-1,4-dihydro-2H-quinazolin-3-yl]-acetic acid methyl ester chemical structure, C23H21BrN2O3, CAS 330850-65-2
[6-Bromo-2-(2-hydroxy-phenyl)-4-phenyl-1,4-dihydro-2H-quinazolin-3-yl]-acetic acid methyl ester
CAS 330850-65-2C23H21BrN2O3
Ethyl 2-[6-bromo-2-(4-methoxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C25H25BrN2O3, CAS 372977-24-7
Ethyl 2-[6-bromo-2-(4-methoxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 372977-24-7C25H25BrN2O3
Ethyl 2-[6-bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C27H29BrN2O5, CAS 373371-43-8
Ethyl 2-[6-bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 373371-43-8C27H29BrN2O5
2-[6-Bromo-2-(2-hydroxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetic acid chemical structure, C22H19BrN2O3, CAS 330850-66-3
2-[6-Bromo-2-(2-hydroxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetic acid
CAS 330850-66-3C22H19BrN2O3
Methyl 2-[6-bromo-2-(2-fluorophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl]acetate chemical structure, C23H20BrFN2O2, CAS 312527-82-5
Methyl 2-[6-bromo-2-(2-fluorophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl]acetate
CAS 312527-82-5C23H20BrFN2O2
Methyl 2-[6-bromo-2-(2-hydroxy-5-methoxy-3-nitrophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C24H22BrN3O6, CAS 312527-87-0
Methyl 2-[6-bromo-2-(2-hydroxy-5-methoxy-3-nitrophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 312527-87-0C24H22BrN3O6
Methyl 2-[6-bromo-2-(4-chlorophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C23H20BrClN2O2, CAS 378766-22-4
Methyl 2-[6-bromo-2-(4-chlorophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 378766-22-4C23H20BrClN2O2
Methyl 2-[6-bromo-2-(4-nitrophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C23H20BrN3O4, CAS 385406-44-0
Methyl 2-[6-bromo-2-(4-nitrophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 385406-44-0C23H20BrN3O4
Quinazoline, 1,2,3,4-tetrahydro-2-(2-nitrophenyl)-4-phenyl- chemical structure, C20H17N3O2, CAS 84571-13-1
Quinazoline, 1,2,3,4-tetrahydro-2-(2-nitrophenyl)-4-phenyl-
CAS 84571-13-1C20H17N3O2
Methyl 2-[6-bromo-2-(2-chlorophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C23H20BrClN2O2, CAS 381692-67-7
Methyl 2-[6-bromo-2-(2-chlorophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 381692-67-7C23H20BrClN2O2
Methyl {6-bromo-2-[4-(dimethylamino)phenyl]-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl}acetate chemical structure, C25H26BrN3O2, CAS 378764-50-2
Methyl {6-bromo-2-[4-(dimethylamino)phenyl]-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl}acetate
CAS 378764-50-2C25H26BrN3O2
Methyl 2-[6-bromo-2-(4-hydroxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C23H21BrN2O3, CAS 380890-81-3
Methyl 2-[6-bromo-2-(4-hydroxyphenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 380890-81-3C23H21BrN2O3
Ethyl 2-[6-bromo-2-(2-fluorophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate chemical structure, C24H22BrFN2O2, CAS 380903-59-3
Ethyl 2-[6-bromo-2-(2-fluorophenyl)-4-phenyl-2,4-dihydro-1H-quinazolin-3-yl]acetate
CAS 380903-59-3C24H22BrFN2O2
N,N-Dimethyl-4-(4-phenyl-1,2,3,4-tetrahydroquinazolin-2-yl)aniline chemical structure, C22H23N3, CAS 84570-90-1
N,N-Dimethyl-4-(4-phenyl-1,2,3,4-tetrahydroquinazolin-2-yl)aniline
CAS 84570-90-1C22H23N3
2-(4-Methoxyphenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline chemical structure, C21H20N2O, CAS 84570-91-2
2-(4-Methoxyphenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline
CAS 84570-91-2C21H20N2O
2-(4-Nitrophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline chemical structure, C20H17N3O2, CAS 84570-92-3
2-(4-Nitrophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline
CAS 84570-92-3C20H17N3O2
2-(3-Nitrophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline chemical structure, C20H17N3O2, CAS 84570-93-4
2-(3-Nitrophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline
CAS 84570-93-4C20H17N3O2
4-(6-Chloro-4-phenyl-1,2,3,4-tetrahydroquinazolin-2-yl)-N,N-dimethylaniline chemical structure, C22H22ClN3, CAS 84570-95-6
4-(6-Chloro-4-phenyl-1,2,3,4-tetrahydroquinazolin-2-yl)-N,N-dimethylaniline
CAS 84570-95-6C22H22ClN3
6-Chloro-2-(4-methoxyphenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline chemical structure, C21H19ClN2O, CAS 84570-97-8
6-Chloro-2-(4-methoxyphenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline
CAS 84570-97-8C21H19ClN2O
6-Chloro-2-(4-nitrophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline chemical structure, C20H16ClN3O2, CAS 84570-99-0
6-Chloro-2-(4-nitrophenyl)-4-phenyl-1,2,3,4-tetrahydroquinazoline
CAS 84570-99-0C20H16ClN3O2