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Murcko scaffold

4-(4-Morpholinyl)-2-phenylquinazoline scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
12
With full pages
5
Scaffold SMILES

c1ccc(-c2nc(N3CCOCC3)c3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-Morpholinyl)-2-phenylquinazoline page
Murcko scaffold c1ccc(-c2nc(N3CCOCC3)c3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-(4-Morpholinyl)-2-phenylquinazoline chemical structure, C18H17N3O, CAS 307544-21-4
4-(4-Morpholinyl)-2-phenylquinazoline
CAS 307544-21-4C18H17N3O
4-[2-(4-Nitrophenyl)quinazolin-4-yl]morpholine chemical structure, C18H16N4O3, CAS 384366-70-5
4-[2-(4-Nitrophenyl)quinazolin-4-yl]morpholine
CAS 384366-70-5C18H16N4O3
4-[2-(2-Chlorophenyl)quinazolin-4-yl]morpholine chemical structure, C18H16ClN3O, CAS 332850-33-6
4-[2-(2-Chlorophenyl)quinazolin-4-yl]morpholine
CAS 332850-33-6C18H16ClN3O
4-[2-(4-Chlorophenyl)quinazolin-4-yl]morpholine chemical structure, C18H16ClN3O, CAS 316125-23-2
4-[2-(4-Chlorophenyl)quinazolin-4-yl]morpholine
CAS 316125-23-2C18H16ClN3O
4-[2-(2-Fluorophenyl)quinazolin-4-yl]morpholine chemical structure, C18H16FN3O, CAS 421564-87-6
4-[2-(2-Fluorophenyl)quinazolin-4-yl]morpholine
CAS 421564-87-6C18H16FN3O
4-[2-(2,4-Dichlorophenyl)quinazolin-4-yl]morpholine chemical structure, C18H15Cl2N3O, CAS 332850-35-8
4-[2-(2,4-Dichlorophenyl)quinazolin-4-yl]morpholine
CAS 332850-35-8C18H15Cl2N3O
4-(2-(4-Fluorophenyl)quinazolin-4-yl)morpholine chemical structure, C18H16FN3O, CAS 683779-98-8
4-(2-(4-Fluorophenyl)quinazolin-4-yl)morpholine
CAS 683779-98-8C18H16FN3O
4-[2-(3,4-Dichlorophenyl)quinazolin-4-yl]morpholine chemical structure, C18H15Cl2N3O, CAS 354992-37-3
4-[2-(3,4-Dichlorophenyl)quinazolin-4-yl]morpholine
CAS 354992-37-3C18H15Cl2N3O
4-[2-(3-Nitrophenyl)quinazolin-4-yl]morpholine chemical structure, C18H16N4O3, CAS 383893-78-5
4-[2-(3-Nitrophenyl)quinazolin-4-yl]morpholine
CAS 383893-78-5C18H16N4O3
4-[2-(4-Propoxyphenyl)quinazolin-4-yl]morpholine chemical structure, C21H23N3O2, CAS 381174-79-4
4-[2-(4-Propoxyphenyl)quinazolin-4-yl]morpholine
CAS 381174-79-4C21H23N3O2
4-[2-(4-Chlorophenyl)quinazolin-4-yl]-2,6-dimethylmorpholine chemical structure, C20H20ClN3O, CAS 308300-08-5
4-[2-(4-Chlorophenyl)quinazolin-4-yl]-2,6-dimethylmorpholine
CAS 308300-08-5C20H20ClN3O
2,6-Dimethyl-4-(2-phenylquinazolin-4-yl)morpholine chemical structure, C20H21N3O, CAS 385420-63-3
2,6-Dimethyl-4-(2-phenylquinazolin-4-yl)morpholine
CAS 385420-63-3C20H21N3O