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Murcko scaffold

1(2H)-Phthalazinone, 2,4-diphenyl- scaffold

42 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
42
With full pages
8
Scaffold SMILES

O=c1c2ccccc2c(-c2ccccc2)nn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1(2H)-Phthalazinone, 2,4-diphenyl- page
Murcko scaffold O=c1c2ccccc2c(-c2ccccc2)nn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

1(2H)-Phthalazinone, 2,4-diphenyl- chemical structure, C20H14N2O, CAS 36503-83-0
1(2H)-Phthalazinone, 2,4-diphenyl-
CAS 36503-83-0C20H14N2O
2-(2-Amino-5-chlorophenyl)-4-phenylphthalazin-1-one chemical structure, C20H14ClN3O, CAS 296770-33-7
2-(2-Amino-5-chlorophenyl)-4-phenylphthalazin-1-one
CAS 296770-33-7C20H14ClN3O
4-(4-Isopropylphenyl)-2-phenyl-1(2H)-phthalazinone chemical structure, C23H20N2O, CAS 106536-60-1
4-(4-Isopropylphenyl)-2-phenyl-1(2H)-phthalazinone
CAS 106536-60-1C23H20N2O
2-(4-Nitrophenyl)-4-phenyl-1(2H)-phthalazinone chemical structure, C20H13N3O3, CAS 57709-78-1
2-(4-Nitrophenyl)-4-phenyl-1(2H)-phthalazinone
CAS 57709-78-1C20H13N3O3
4-(4-Hydroxyphenyl)-2-[3-(trifluoromethyl)phenyl]-1(2H)-phthalazinone chemical structure, C21H13F3N2O2, CAS 486994-81-4
4-(4-Hydroxyphenyl)-2-[3-(trifluoromethyl)phenyl]-1(2H)-phthalazinone
CAS 486994-81-4C21H13F3N2O2
2-(3,4-Dichlorophenyl)-4-phenylphthalazin-1(2H)-one chemical structure, C20H12Cl2N2O, CAS 332056-25-4
2-(3,4-Dichlorophenyl)-4-phenylphthalazin-1(2H)-one
CAS 332056-25-4C20H12Cl2N2O
2-(5-Chloro-2-nitrophenyl)-4-(4-fluorophenyl)phthalazin-1-one chemical structure, C20H11ClFN3O3, CAS 329922-56-7
2-(5-Chloro-2-nitrophenyl)-4-(4-fluorophenyl)phthalazin-1-one
CAS 329922-56-7C20H11ClFN3O3
3-Nitro-4-(1-oxo-4-phenylphthalazin-2(1H)-yl)benzonitrile chemical structure, C21H12N4O3, CAS 355435-65-3
3-Nitro-4-(1-oxo-4-phenylphthalazin-2(1H)-yl)benzonitrile
CAS 355435-65-3C21H12N4O3
2-(5-Chloro-2-nitro-phenyl)-4-(4-ethyl-phenyl)-2H-phthalazin-1-one chemical structure, C22H16ClN3O3, CAS 300730-53-4
2-(5-Chloro-2-nitro-phenyl)-4-(4-ethyl-phenyl)-2H-phthalazin-1-one
CAS 300730-53-4C22H16ClN3O3
4-(4-Chlorophenyl)-2-(4-fluorophenyl)-1(2H)-phthalazinone chemical structure, C20H12ClFN2O, CAS 338756-80-2
4-(4-Chlorophenyl)-2-(4-fluorophenyl)-1(2H)-phthalazinone
CAS 338756-80-2C20H12ClFN2O
2-(4-Bromophenyl)-7-fluoro-4-(4-fluorophenyl)-1(2H)-phthalazinone chemical structure, C20H11BrF2N2O, CAS 478066-05-6
2-(4-Bromophenyl)-7-fluoro-4-(4-fluorophenyl)-1(2H)-phthalazinone
CAS 478066-05-6C20H11BrF2N2O
2-(4-Chlorophenyl)-7-fluoro-4-(4-fluorophenyl)-1(2H)-phthalazinone chemical structure, C20H11ClF2N2O, CAS 161716-20-7
2-(4-Chlorophenyl)-7-fluoro-4-(4-fluorophenyl)-1(2H)-phthalazinone
CAS 161716-20-7C20H11ClF2N2O
7-Fluoro-2,4-bis(4-fluorophenyl)-1(2H)-phthalazinone chemical structure, C20H11F3N2O, CAS 339009-71-1
7-Fluoro-2,4-bis(4-fluorophenyl)-1(2H)-phthalazinone
CAS 339009-71-1C20H11F3N2O
7-Fluoro-4-(4-fluorophenyl)-2-[4-(trifluoromethyl)phenyl]-1(2H)-phthalazinone chemical structure, C21H11F5N2O, CAS 339009-72-2
7-Fluoro-4-(4-fluorophenyl)-2-[4-(trifluoromethyl)phenyl]-1(2H)-phthalazinone
CAS 339009-72-2C21H11F5N2O
2-(5-Chloro-2-nitrophenyl)-4-(4-methylphenyl)phthalazin-1-one chemical structure, C21H14ClN3O3, CAS 642429-76-3
2-(5-Chloro-2-nitrophenyl)-4-(4-methylphenyl)phthalazin-1-one
CAS 642429-76-3C21H14ClN3O3
2,4-Bis(4-chlorophenyl)phthalazin-1-one chemical structure, C20H12Cl2N2O, CAS 478048-21-4
2,4-Bis(4-chlorophenyl)phthalazin-1-one
CAS 478048-21-4C20H12Cl2N2O
4-(4-Chlorophenyl)-2-phenyl-1(2H)-phthalazinone chemical structure, C20H13ClN2O, CAS 57709-77-0
4-(4-Chlorophenyl)-2-phenyl-1(2H)-phthalazinone
CAS 57709-77-0C20H13ClN2O
4-(4-Chlorophenyl)-2-[4-(trifluoromethoxy)phenyl]phthalazin-1-one chemical structure, C21H12ClF3N2O2, CAS 478048-28-1
4-(4-Chlorophenyl)-2-[4-(trifluoromethoxy)phenyl]phthalazin-1-one
CAS 478048-28-1C21H12ClF3N2O2
6,7-Dichloro-2,4-bis(4-chlorophenyl)phthalazin-1-one chemical structure, C20H10Cl4N2O, CAS 672951-09-6
6,7-Dichloro-2,4-bis(4-chlorophenyl)phthalazin-1-one
CAS 672951-09-6C20H10Cl4N2O
RefChem:381434 chemical structure, C21H16N2O, CAS 57709-75-8
RefChem:381434
CAS 57709-75-8C21H16N2O
6,7-Dichloro-2-(4-chlorophenyl)-4-(4-fluorophenyl)phthalazin-1-one chemical structure, C20H10Cl3FN2O, CAS 161716-25-2
6,7-Dichloro-2-(4-chlorophenyl)-4-(4-fluorophenyl)phthalazin-1-one
CAS 161716-25-2C20H10Cl3FN2O
4-(4-Chlorophenyl)-2-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]phthalazin-1-one chemical structure, C23H17Cl3N2O3, CAS 400087-11-8
4-(4-Chlorophenyl)-2-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]phthalazin-1-one
CAS 400087-11-8C23H17Cl3N2O3
4-(5-Chloro-2-hydroxyphenyl)-2-phenyl-1(2H)-phthalazinone chemical structure, C20H13ClN2O2, CAS 401607-13-4
4-(5-Chloro-2-hydroxyphenyl)-2-phenyl-1(2H)-phthalazinone
CAS 401607-13-4C20H13ClN2O2
2-(4-Chlorophenyl)-4-(4-fluorophenyl)-1(2H)-phthalazinone chemical structure, C20H12ClFN2O, CAS 161716-18-3
2-(4-Chlorophenyl)-4-(4-fluorophenyl)-1(2H)-phthalazinone
CAS 161716-18-3C20H12ClFN2O