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Murcko scaffold

Ring system with 4 rings and 22 atoms

49 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 49
With full pages: 6

Scaffold SMILES

c1ccc(-c2cc(N3CCNCC3)c3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(-c2cc(N3CCNCC3)c3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

4-(4-Methylpiperazino)-2-phenylquinoline chemical structure, C20H21N3, CAS 181775-68-8

4-(4-Methylpiperazino)-2-phenylquinoline

CAS 181775-68-8C₂₀H₂₁N₃

2-(4-tert-Butylphenyl)-4-(4-methyl-1-piperazinyl)quinoline dihydrochloride chemical structure, C24H31Cl2N3, CAS 853344-32-8

2-(4-tert-Butylphenyl)-4-(4-methyl-1-piperazinyl)quinoline dihydrochloride

CAS 853344-32-8C₂₄H₃₁Cl₂N₃

2-(4-Ethylphenyl)-4-(4-methyl-1-piperazinyl)quinoline hydrobromide chemical structure, C22H26BrN3, CAS 853349-59-4

2-(4-Ethylphenyl)-4-(4-methyl-1-piperazinyl)quinoline hydrobromide

CAS 853349-59-4C₂₂H₂₆BrN₃

2-(4-Ethylphenyl)-4-(4-methyl-1-piperazinyl)quinoline hydrochloride chemical structure, C22H26ClN3, CAS 853349-62-9

2-(4-Ethylphenyl)-4-(4-methyl-1-piperazinyl)quinoline hydrochloride

CAS 853349-62-9C₂₂H₂₆ClN₃

2-(4-Methoxyphenyl)-4-(4-methyl-1-piperazinyl) quinoline hydrobromide chemical structure, C21H24ClN3O, CAS 853333-45-6

2-(4-Methoxyphenyl)-4-(4-methyl-1-piperazinyl) quinoline hydrobromide

CAS 853333-45-6C₂₁H₂₄ClN₃O

2-(4-Methoxyphenyl)-4-(2-methyl-1-piperazinyl)quinoline hydrobromide chemical structure, C21H24BrN3O, CAS 853333-46-7

2-(4-Methoxyphenyl)-4-(2-methyl-1-piperazinyl)quinoline hydrobromide

CAS 853333-46-7C₂₁H₂₄BrN₃O

2-Phenyl-4-(piperazin-1-yl)-6-(trifluoromethoxy)quinoline hydrochloride chemical structure, C20H19ClF3N3O, CAS 1333257-55-8

2-Phenyl-4-(piperazin-1-yl)-6-(trifluoromethoxy)quinoline hydrochloride

CAS 1333257-55-8C₂₀H₁₉ClF₃N₃O

2-Phenyl-4-(piperazin-1-yl)-6-(trifluoromethyl)quinoline hydrochloride chemical structure, C20H19ClF3N3, CAS 1333256-92-0

2-Phenyl-4-(piperazin-1-yl)-6-(trifluoromethyl)quinoline hydrochloride

CAS 1333256-92-0C₂₀H₁₉ClF₃N₃

2-Phenyl-4-(piperazin-1-yl)-7-(trifluoromethoxy)quinoline hydrochloride chemical structure, C20H19ClF3N3O, CAS 1333254-97-9

2-Phenyl-4-(piperazin-1-yl)-7-(trifluoromethoxy)quinoline hydrochloride

CAS 1333254-97-9C₂₀H₁₉ClF₃N₃O

2-Phenyl-4-(piperazin-1-yl)-7-(trifluoromethyl)quinoline hydrochloride chemical structure, C20H19ClF3N3, CAS 1333257-75-2

2-Phenyl-4-(piperazin-1-yl)-7-(trifluoromethyl)quinoline hydrochloride

CAS 1333257-75-2C₂₀H₁₉ClF₃N₃

2-Phenyl-4-(piperazin-1-yl)-8-(trifluoromethoxy)quinoline hydrochloride chemical structure, C20H19ClF3N3O, CAS 1333253-20-5

2-Phenyl-4-(piperazin-1-yl)-8-(trifluoromethoxy)quinoline hydrochloride

CAS 1333253-20-5C₂₀H₁₉ClF₃N₃O

2-Phenyl-4-(piperazin-1-yl)-8-(trifluoromethyl)quinoline hydrochloride chemical structure, C20H19ClF3N3, CAS 1333258-42-6

2-Phenyl-4-(piperazin-1-yl)-8-(trifluoromethyl)quinoline hydrochloride

CAS 1333258-42-6C₂₀H₁₉ClF₃N₃

2-Phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H20ClN3, CAS 1333253-32-9

2-Phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333253-32-9C₁₉H₂₀ClN₃

5,7-Dichloro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H18Cl3N3, CAS 1333257-72-9

5,7-Dichloro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333257-72-9C₁₉H₁₈Cl₃N₃

5,7-Difluoro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H18ClF2N3, CAS 1333253-40-9

5,7-Difluoro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333253-40-9C₁₉H₁₈ClF₂N₃

5,7-Dimethyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C21H24ClN3, CAS 1333257-78-5

5,7-Dimethyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333257-78-5C₂₁H₂₄ClN₃

5,8-Dichloro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H18Cl3N3, CAS 1333258-08-4

5,8-Dichloro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333258-08-4C₁₉H₁₈Cl₃N₃

5,8-Difluoro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H18ClF2N3, CAS 1333258-06-2

5,8-Difluoro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333258-06-2C₁₉H₁₈ClF₂N₃

5,8-Dimethyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C21H24ClN3, CAS 1333249-89-0

5,8-Dimethyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333249-89-0C₂₁H₂₄ClN₃

5-Chloro-8-methyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C20H21Cl2N3, CAS 1333253-41-0

5-Chloro-8-methyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333253-41-0C₂₀H₂₁Cl₂N₃

6,8-Dichloro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H18Cl3N3, CAS 1333251-78-7

6,8-Dichloro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333251-78-7C₁₉H₁₈Cl₃N₃

6,8-Difluoro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H18ClF2N3, CAS 1333257-61-6

6,8-Difluoro-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333257-61-6C₁₉H₁₈ClF₂N₃

6,8-Dimethyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C21H24ClN3, CAS 1333257-62-7

6,8-Dimethyl-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333257-62-7C₂₁H₂₄ClN₃

6-Bromo-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride chemical structure, C19H19BrClN3, CAS 1333257-35-4

6-Bromo-2-phenyl-4-(piperazin-1-yl)quinoline hydrochloride

CAS 1333257-35-4C₁₉H₁₉BrClN₃