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Murcko scaffold

Ring system with 4 rings and 22 atoms

21 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
21
With full pages
5
Scaffold SMILES

c1ccc(C2=Nc3ccccc3C(c3ccccc3)N2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2=Nc3ccccc3C(c3ccccc3)N2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

(6-Bromo-2,4-diphenylquinazolin-3(4H)-yl)acetic acid chemical structure, C22H17BrN2O2, CAS 313650-47-4
(6-Bromo-2,4-diphenylquinazolin-3(4H)-yl)acetic acid
CAS 313650-47-4C22H17BrN2O2
Methyl 2-(6-bromo-2,4-diphenyl-4H-quinazolin-3-yl)acetate chemical structure, C23H19BrN2O2, CAS 314047-08-0
Methyl 2-(6-bromo-2,4-diphenyl-4H-quinazolin-3-yl)acetate
CAS 314047-08-0C23H19BrN2O2
Methyl [6-bromo-2-(2-chlorophenyl)-4-phenylquinazolin-3(4H)-yl]acetate chemical structure, C23H18BrClN2O2, CAS 328271-34-7
Methyl [6-bromo-2-(2-chlorophenyl)-4-phenylquinazolin-3(4H)-yl]acetate
CAS 328271-34-7C23H18BrClN2O2
Methyl 2-[6-bromo-2-(2-bromophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate chemical structure, C23H18Br2N2O2, CAS 313267-12-8
Methyl 2-[6-bromo-2-(2-bromophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate
CAS 313267-12-8C23H18Br2N2O2
Methyl [6-bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]acetate chemical structure, C26H25BrN2O5, CAS 313267-97-9
Methyl [6-bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]acetate
CAS 313267-97-9C26H25BrN2O5
Ethyl 2-[6-bromo-2-(3-chlorophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate chemical structure, C24H20BrClN2O2, CAS 313268-61-0
Ethyl 2-[6-bromo-2-(3-chlorophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate
CAS 313268-61-0C24H20BrClN2O2
Ethyl 2-(6-bromo-2-(4-chlorophenyl)-4-phenylquinazolin-3(4H)-yl)acetate chemical structure, C24H20BrClN2O2, CAS 313268-62-1
Ethyl 2-(6-bromo-2-(4-chlorophenyl)-4-phenylquinazolin-3(4H)-yl)acetate
CAS 313268-62-1C24H20BrClN2O2
[6-Bromo-2-(3-chloro-phenyl)-4-phenyl-4H-quinazolin-3-yl]-acetic acid hydrazide chemical structure, C22H18BrClN4O, CAS 332018-93-6
[6-Bromo-2-(3-chloro-phenyl)-4-phenyl-4H-quinazolin-3-yl]-acetic acid hydrazide
CAS 332018-93-6C22H18BrClN4O
Methyl 2-[6-methyl-4-phenyl-2-(3,4,5-trimethoxyphenyl)-4H-quinazolin-3-yl]acetate chemical structure, C27H28N2O5, CAS 313267-96-8
Methyl 2-[6-methyl-4-phenyl-2-(3,4,5-trimethoxyphenyl)-4H-quinazolin-3-yl]acetate
CAS 313267-96-8C27H28N2O5
2-(6-Bromo-2,4-diphenylquinazolin-3(4H)-yl)acetohydrazide chemical structure, C22H19BrN4O, CAS 328540-91-6
2-(6-Bromo-2,4-diphenylquinazolin-3(4H)-yl)acetohydrazide
CAS 328540-91-6C22H19BrN4O
2-[6-Bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)-4H-quinazolin-3-yl]acetohydrazide chemical structure, C25H25BrN4O4, CAS 372493-84-0
2-[6-Bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)-4H-quinazolin-3-yl]acetohydrazide
CAS 372493-84-0C25H25BrN4O4
2-[6-Bromo-2-(4-methoxyphenyl)-4-phenyl-4H-quinazolin-3-yl]acetohydrazide chemical structure, C23H21BrN4O2, CAS 375835-56-6
2-[6-Bromo-2-(4-methoxyphenyl)-4-phenyl-4H-quinazolin-3-yl]acetohydrazide
CAS 375835-56-6C23H21BrN4O2
Ethyl [6-bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]acetate chemical structure, C27H27BrN2O5, CAS 353253-21-1
Ethyl [6-bromo-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]acetate
CAS 353253-21-1C27H27BrN2O5
Methyl 2-[6-bromo-2-(4-methoxyphenyl)-4-phenyl-4H-quinazolin-3-yl]acetate chemical structure, C24H21BrN2O3, CAS 375358-29-5
Methyl 2-[6-bromo-2-(4-methoxyphenyl)-4-phenyl-4H-quinazolin-3-yl]acetate
CAS 375358-29-5C24H21BrN2O3
Methyl (6-chloro-2,4-diphenyl-3(4H)-quinazolinyl)acetate chemical structure, C23H19ClN2O2, CAS 374769-91-2
Methyl (6-chloro-2,4-diphenyl-3(4H)-quinazolinyl)acetate
CAS 374769-91-2C23H19ClN2O2
Methyl [6-bromo-2-(4-bromophenyl)-4-phenylquinazolin-3(4H)-yl]acetate chemical structure, C23H18Br2N2O2, CAS 312734-18-2
Methyl [6-bromo-2-(4-bromophenyl)-4-phenylquinazolin-3(4H)-yl]acetate
CAS 312734-18-2C23H18Br2N2O2
Methyl 2-[6-bromo-2-(3-chlorophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate chemical structure, C23H18BrClN2O2, CAS 313268-60-9
Methyl 2-[6-bromo-2-(3-chlorophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate
CAS 313268-60-9C23H18BrClN2O2
Methyl 2-(6-methyl-2,4-diphenyl-3,4-dihydroquinazolin-3-yl)acetate chemical structure, C24H22N2O2, CAS 313968-09-1
Methyl 2-(6-methyl-2,4-diphenyl-3,4-dihydroquinazolin-3-yl)acetate
CAS 313968-09-1C24H22N2O2
Ethyl 2-[6-bromo-2-(4-bromophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate chemical structure, C24H20Br2N2O2, CAS 328541-03-3
Ethyl 2-[6-bromo-2-(4-bromophenyl)-4-phenyl-4H-quinazolin-3-yl]acetate
CAS 328541-03-3C24H20Br2N2O2
6-Methyl-2,4-diphenyl-1,4-dihydroquinazoline chemical structure, C21H18N2, CAS 128256-22-4
6-Methyl-2,4-diphenyl-1,4-dihydroquinazoline
CAS 128256-22-4C21H18N2
Methyl 2-(6-methyl-4-phenyl-2-(2,3,4-trimethoxyphenyl)quinazolin-3(4H)-yl)acetate chemical structure, C27H28N2O5, CAS 1795413-07-8
Methyl 2-(6-methyl-4-phenyl-2-(2,3,4-trimethoxyphenyl)quinazolin-3(4H)-yl)acetate
CAS 1795413-07-8C27H28N2O5