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Murcko scaffold

2,4-Diphenylquinoline scaffold

60 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
60
With full pages
4
Scaffold SMILES

c1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,4-Diphenylquinoline page
Murcko scaffold c1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

6-Chloro-2-(4-methoxyphenyl)-4-phenylquinoline chemical structure, C22H16ClNO, CAS 21923-46-6
6-Chloro-2-(4-methoxyphenyl)-4-phenylquinoline
CAS 21923-46-6C22H16ClNO
6-Chloro-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinoline chemical structure, C24H20ClNO3, CAS 21923-49-9
6-Chloro-4-phenyl-2-(3,4,5-trimethoxyphenyl)quinoline
CAS 21923-49-9C24H20ClNO3
3-Methyl-2,4-diphenylquinoline chemical structure, C22H17N, CAS 10266-13-4
3-Methyl-2,4-diphenylquinoline
CAS 10266-13-4C22H17N
6-Chloro-2,4-diphenylquinoline chemical structure, C21H14ClN, CAS 21923-40-0
6-Chloro-2,4-diphenylquinoline
CAS 21923-40-0C21H14ClN
6-Nitro-2,4-diphenyl-quinoline chemical structure, C21H14N2O2, CAS 138432-74-3
6-Nitro-2,4-diphenyl-quinoline
CAS 138432-74-3C21H14N2O2
p-(6-Chloro-4-phenyl-2-quinolyl)aniline chemical structure, C21H15ClN2, CAS 21923-52-4
p-(6-Chloro-4-phenyl-2-quinolyl)aniline
CAS 21923-52-4C21H15ClN2
6-Chloro-2-(4-chlorophenyl)-4-phenylquinoline chemical structure, C21H13Cl2N, CAS 21923-45-5
6-Chloro-2-(4-chlorophenyl)-4-phenylquinoline
CAS 21923-45-5C21H13Cl2N
6-Chloro-2-(4-nitrophenyl)-4-phenylquinoline chemical structure, C21H13ClN2O2, CAS 313233-84-0
6-Chloro-2-(4-nitrophenyl)-4-phenylquinoline
CAS 313233-84-0C21H13ClN2O2
2-(4-Bromophenyl)-6-methyl-4-phenylquinoline chemical structure, C22H16BrN, CAS 71858-09-8
2-(4-Bromophenyl)-6-methyl-4-phenylquinoline
CAS 71858-09-8C22H16BrN
6-Chloro-2-(3,4-dimethoxyphenyl)-4-phenylquinoline chemical structure, C23H18ClNO2, CAS 21923-47-7
6-Chloro-2-(3,4-dimethoxyphenyl)-4-phenylquinoline
CAS 21923-47-7C23H18ClNO2
6-Bromo-2-(4-methoxyphenyl)-4-phenylquinoline chemical structure, C22H16BrNO, CAS 71858-14-5
6-Bromo-2-(4-methoxyphenyl)-4-phenylquinoline
CAS 71858-14-5C22H16BrNO
2-(4-Bromophenyl)-6-chloro-4-phenylquinoline chemical structure, C21H13BrClN, CAS 21923-43-3
2-(4-Bromophenyl)-6-chloro-4-phenylquinoline
CAS 21923-43-3C21H13BrClN
6-Bromo-2-(4-bromophenyl)-4-phenylquinoline chemical structure, C21H13Br2N, CAS 71858-13-4
6-Bromo-2-(4-bromophenyl)-4-phenylquinoline
CAS 71858-13-4C21H13Br2N
2-[4-(6-Bromo-4-phenylquinolin-2-yl)phenoxy]acetohydrazide chemical structure, C23H18BrN3O2, CAS 136987-58-1
2-[4-(6-Bromo-4-phenylquinolin-2-yl)phenoxy]acetohydrazide
CAS 136987-58-1C23H18BrN3O2
2-[4-(6-Chloro-4-phenylquinolin-2-yl)phenoxy]acetohydrazide chemical structure, C23H18ClN3O2, CAS 337483-13-3
2-[4-(6-Chloro-4-phenylquinolin-2-yl)phenoxy]acetohydrazide
CAS 337483-13-3C23H18ClN3O2
2-[4-(6-Methyl-4-phenylquinolin-2-yl)phenoxy]acetohydrazide chemical structure, C24H21N3O2, CAS 337483-31-5
2-[4-(6-Methyl-4-phenylquinolin-2-yl)phenoxy]acetohydrazide
CAS 337483-31-5C24H21N3O2
N-[4-(6-Chloro-4-phenylquinolin-2-yl)phenyl]methanesulfonamide chemical structure, C22H17ClN2O2S, CAS 710986-91-7
N-[4-(6-Chloro-4-phenylquinolin-2-yl)phenyl]methanesulfonamide
CAS 710986-91-7C22H17ClN2O2S
4-(6-Bromo-4-(2-chlorophenyl)quinolin-2-yl)phenol chemical structure, C21H13BrClNO, CAS 202192-75-4
4-(6-Bromo-4-(2-chlorophenyl)quinolin-2-yl)phenol
CAS 202192-75-4C21H13BrClNO
4-(6-Methyl-4-phenyl-2-quinolinyl)phenol chemical structure, C22H17NO, CAS 385400-64-6
4-(6-Methyl-4-phenyl-2-quinolinyl)phenol
CAS 385400-64-6C22H17NO
2,4-Diphenylquinoline chemical structure, C21H15N, CAS 1039-51-6
2,4-Diphenylquinoline
CAS 1039-51-6C21H15N
4-(6-Bromo-4-phenylquinolin-2-yl)phenol chemical structure, C21H14BrNO, CAS 202192-66-3
4-(6-Bromo-4-phenylquinolin-2-yl)phenol
CAS 202192-66-3C21H14BrNO
Ethyl 2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]acetate chemical structure, C25H20BrNO3, CAS 136987-56-9
Ethyl 2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]acetate
CAS 136987-56-9C25H20BrNO3
Ethyl 2-[4-(6-chloro-4-phenylquinolin-2-yl)phenoxy]acetate chemical structure, C25H20ClNO3, CAS 333767-09-2
Ethyl 2-[4-(6-chloro-4-phenylquinolin-2-yl)phenoxy]acetate
CAS 333767-09-2C25H20ClNO3
Ethyl 2-[4-(6-methyl-4-phenylquinolin-2-yl)phenoxy]acetate chemical structure, C26H23NO3, CAS 337483-29-1
Ethyl 2-[4-(6-methyl-4-phenylquinolin-2-yl)phenoxy]acetate
CAS 337483-29-1C26H23NO3