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Murcko scaffold

2-Phenyl-4-(1-piperidinyl)quinazoline scaffold

21 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
21
With full pages
6
Scaffold SMILES

c1ccc(-c2nc(N3CCCCC3)c3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-4-(1-piperidinyl)quinazoline page
Murcko scaffold c1ccc(-c2nc(N3CCCCC3)c3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

2-(4-(4-Methylpiperidin-1-yl)quinazolin-2-yl)phenol chemical structure, C20H21N3O, CAS 354993-43-4
2-(4-(4-Methylpiperidin-1-yl)quinazolin-2-yl)phenol
CAS 354993-43-4C20H21N3O
6-Chloro-2-phenyl-4-piperidin-1-ylquinazoline chemical structure, C19H18ClN3, CAS 350246-90-1
6-Chloro-2-phenyl-4-piperidin-1-ylquinazoline
CAS 350246-90-1C19H18ClN3
4-(4-Methyl-1-piperidinyl)-2-phenylquinazoline chemical structure, C20H21N3, CAS 307544-24-7
4-(4-Methyl-1-piperidinyl)-2-phenylquinazoline
CAS 307544-24-7C20H21N3
2-Phenyl-4-(1-piperidinyl)quinazoline chemical structure, C19H19N3, CAS 332071-25-7
2-Phenyl-4-(1-piperidinyl)quinazoline
CAS 332071-25-7C19H19N3
2-(4-Bromophenyl)-4-piperidin-1-ylquinazoline chemical structure, C19H18BrN3, CAS 352657-22-8
2-(4-Bromophenyl)-4-piperidin-1-ylquinazoline
CAS 352657-22-8C19H18BrN3
2-(4-Fluorophenyl)-4-(piperidin-1-yl)quinazoline chemical structure, C19H18FN3, CAS 503432-04-0
2-(4-Fluorophenyl)-4-(piperidin-1-yl)quinazoline
CAS 503432-04-0C19H18FN3
2-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)quinazoline chemical structure, C20H20FN3, CAS 683779-97-7
2-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)quinazoline
CAS 683779-97-7C20H20FN3
2-(4-Methoxyphenyl)-4-(piperidin-1-yl)quinazoline chemical structure, C20H21N3O, CAS 503432-75-5
2-(4-Methoxyphenyl)-4-(piperidin-1-yl)quinazoline
CAS 503432-75-5C20H21N3O
2-(4-Bromophenyl)-4-(4-methylpiperidin-1-yl)quinazoline chemical structure, C20H20BrN3, CAS 317842-27-6
2-(4-Bromophenyl)-4-(4-methylpiperidin-1-yl)quinazoline
CAS 317842-27-6C20H20BrN3
2-(4-(3,5-Dimethylpiperidin-1-yl)quinazolin-2-yl)phenol chemical structure, C21H23N3O, CAS 421572-99-8
2-(4-(3,5-Dimethylpiperidin-1-yl)quinazolin-2-yl)phenol
CAS 421572-99-8C21H23N3O
2-[4-(3-Methylpiperidin-1-yl)quinazolin-2-yl]phenol chemical structure, C20H21N3O, CAS 442653-02-3
2-[4-(3-Methylpiperidin-1-yl)quinazolin-2-yl]phenol
CAS 442653-02-3C20H21N3O
2-(4-(2-Methylpiperidin-1-yl)quinazolin-2-yl)phenol chemical structure, C20H21N3O, CAS 378752-33-1
2-(4-(2-Methylpiperidin-1-yl)quinazolin-2-yl)phenol
CAS 378752-33-1C20H21N3O
2-(2-Fluorophenyl)-4-(3-methylpiperidin-1-yl)quinazoline chemical structure, C20H20FN3, CAS 422561-35-1
2-(2-Fluorophenyl)-4-(3-methylpiperidin-1-yl)quinazoline
CAS 422561-35-1C20H20FN3
2-Methoxy-6-(4-(3-methylpiperidin-1-yl)quinazolin-2-yl)phenol chemical structure, C21H23N3O2, CAS 799806-83-0
2-Methoxy-6-(4-(3-methylpiperidin-1-yl)quinazolin-2-yl)phenol
CAS 799806-83-0C21H23N3O2
2-[4-(4-Amino-piperidin-1-yl)-7-methyl-quinazolin-2-yl]-phenol chemical structure, C20H22N4O, CAS 757981-49-0
2-[4-(4-Amino-piperidin-1-yl)-7-methyl-quinazolin-2-yl]-phenol
CAS 757981-49-0C20H22N4O
2-(4-(4-Aminopiperidin-1-yl)-7-methylquinazolin-2-yl)-3-fluorophenol chemical structure, C20H21FN4O, CAS 879275-46-4
2-(4-(4-Aminopiperidin-1-yl)-7-methylquinazolin-2-yl)-3-fluorophenol
CAS 879275-46-4C20H21FN4O
1-(2-(2-Hydroxyphenyl)-7-methylquinazolin-4-yl)piperidine-3-carboxylic acid chemical structure, C21H21N3O3, CAS 879275-22-6
1-(2-(2-Hydroxyphenyl)-7-methylquinazolin-4-yl)piperidine-3-carboxylic acid
CAS 879275-22-6C21H21N3O3
2-(4-(4-Aminopiperidin-1-yl)quinazolin-2-yl)phenol chemical structure, C19H20N4O, CAS 879275-44-2
2-(4-(4-Aminopiperidin-1-yl)quinazolin-2-yl)phenol
CAS 879275-44-2C19H20N4O
2-(4-(4-Aminopiperidin-1-yl)-6-fluoroquinazolin-2-yl)phenol chemical structure, C19H19FN4O, CAS 879275-47-5
2-(4-(4-Aminopiperidin-1-yl)-6-fluoroquinazolin-2-yl)phenol
CAS 879275-47-5C19H19FN4O
tert-Butyl 1-(2-(2-hydroxyphenyl)quinazolin-4-yl)piperidin-4-ylcarbamate chemical structure, C24H28N4O3, CAS 879275-43-1
tert-Butyl 1-(2-(2-hydroxyphenyl)quinazolin-4-yl)piperidin-4-ylcarbamate
CAS 879275-43-1C24H28N4O3
2-(4-(3-(Aminomethyl)piperidin-1-yl)-7-methylquinazolin-2-yl)phenol chemical structure, C21H24N4O, CAS 879275-28-2
2-(4-(3-(Aminomethyl)piperidin-1-yl)-7-methylquinazolin-2-yl)phenol
CAS 879275-28-2C21H24N4O