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Murcko scaffold

1-Morpholin-4-yl-2-(5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone scaffold

17 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 17
With full pages: 5

Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)[nH]1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Morpholin-4-yl-2-(5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone page

Murcko scaffold O=C(CSc1nnc(-c2ccccc2)[nH]1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-[[5-(4-tert-Butylphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C19H26N4O2S, CAS 313400-75-8

2-[[5-(4-tert-Butylphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 313400-75-8C₁₉H₂₆N₄O₂S

2-[(4-Methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-morpholin-4-ylethanone chemical structure, C15H18N4O2S, CAS 482653-72-5

2-[(4-Methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-morpholin-4-ylethanone

CAS 482653-72-5C₁₅H₁₈N₄O₂S

2-[[5-(2-Methoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C15H18N4O3S, CAS 634167-48-9

2-[[5-(2-Methoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 634167-48-9C₁₅H₁₈N₄O₃S

1-Morpholin-4-yl-2-(5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone chemical structure, C14H16N4O2S, CAS 457943-72-5

1-Morpholin-4-yl-2-(5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone

CAS 457943-72-5C₁₄H₁₆N₄O₂S

2-[[5-(4-Chlorophenyl)-4-propyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C17H21ClN4O2S, CAS 663214-40-2

2-[[5-(4-Chlorophenyl)-4-propyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 663214-40-2C₁₇H₂₁ClN₄O₂S

2-[[4-Methyl-5-(4-nitrophenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C15H17N5O4S, CAS 482659-92-7

2-[[4-Methyl-5-(4-nitrophenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 482659-92-7C₁₅H₁₇N₅O₄S

2-[[5-(2,4-Dichlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C17H18Cl2N4O2S, CAS 727368-81-2

2-[[5-(2,4-Dichlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 727368-81-2C₁₇H₁₈Cl₂N₄O₂S

N-[4-[4-Methyl-5-(2-morpholin-4-yl-2-oxoethyl)sulfanyl-1,2,4-triazol-3-yl]phenyl]acetamide chemical structure, C17H21N5O3S, CAS 500266-36-4

N-[4-[4-Methyl-5-(2-morpholin-4-yl-2-oxoethyl)sulfanyl-1,2,4-triazol-3-yl]phenyl]acetamide

CAS 500266-36-4C₁₇H₂₁N₅O₃S

2-[[5-(4-Chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C16H19ClN4O2S, CAS 332934-69-7

2-[[5-(4-Chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 332934-69-7C₁₆H₁₉ClN₄O₂S

1-Morpholin-4-yl-2-[[5-(4-nitrophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C17H19N5O4S, CAS 692774-19-9

1-Morpholin-4-yl-2-[[5-(4-nitrophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]ethanone

CAS 692774-19-9C₁₇H₁₉N₅O₄S

2-[[5-(4-Ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C16H20N4O2S, CAS 852296-47-0

2-[[5-(4-Ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 852296-47-0C₁₆H₂₀N₄O₂S

2-((4-Allyl-5-(5-bromo-2-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-1-morpholinoethanone chemical structure, C17H19BrN4O3S, CAS 892194-89-7

2-((4-Allyl-5-(5-bromo-2-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-1-morpholinoethanone

CAS 892194-89-7C₁₇H₁₉BrN₄O₃S

2-((4-Ethyl-5-(2-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-1-morpholinoethanone chemical structure, C16H20N4O3S, CAS 831243-81-3

2-((4-Ethyl-5-(2-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-1-morpholinoethanone

CAS 831243-81-3C₁₆H₂₀N₄O₃S

2-((5-(5-Bromo-2-hydroxyphenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-1-morpholinoethanone chemical structure, C16H19BrN4O3S, CAS 896656-65-8

2-((5-(5-Bromo-2-hydroxyphenyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-1-morpholinoethanone

CAS 896656-65-8C₁₆H₁₉BrN₄O₃S

2-[[5-(2-Methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C16H20N4O3S, CAS 892699-82-0

2-[[5-(2-Methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 892699-82-0C₁₆H₂₀N₄O₃S

2-[[5-(3-Methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone chemical structure, C16H20N4O3S, CAS 876903-84-3

2-[[5-(3-Methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylethanone

CAS 876903-84-3C₁₆H₂₀N₄O₃S

2-[[5-(4-Methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylpropan-1-one chemical structure, C16H20N4O2S, CAS 1016488-70-2

2-[[5-(4-Methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-1-morpholin-4-ylpropan-1-one

CAS 1016488-70-2C₁₆H₂₀N₄O₂S