CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)Nc1cccc2ncccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1cccc2ncccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(2-Chloro-6-fluorophenyl)-N-quinolin-5-ylacetamide chemical structure, C17H12ClFN2O, CAS 746606-04-2
2-(2-Chloro-6-fluorophenyl)-N-quinolin-5-ylacetamide
CAS 746606-04-2C17H12ClFN2O
2-(3,4-Dichlorophenyl)-N-quinolin-5-ylacetamide chemical structure, C17H12Cl2N2O, CAS 749880-13-5
2-(3,4-Dichlorophenyl)-N-quinolin-5-ylacetamide
CAS 749880-13-5C17H12Cl2N2O
2-(4-Chlorophenyl)-N-quinolin-5-ylacetamide chemical structure, C17H13ClN2O, CAS 712291-94-6
2-(4-Chlorophenyl)-N-quinolin-5-ylacetamide
CAS 712291-94-6C17H13ClN2O
2-(4-Methoxyphenyl)-N-(quinolin-5-yl)acetamide chemical structure, C18H16N2O2, CAS 857039-84-0
2-(4-Methoxyphenyl)-N-(quinolin-5-yl)acetamide
CAS 857039-84-0C18H16N2O2
2-(4-Chlorophenyl)-N-(2-methylquinolin-5-yl)acetamide chemical structure, C18H15ClN2O, CAS 890196-76-6
2-(4-Chlorophenyl)-N-(2-methylquinolin-5-yl)acetamide
CAS 890196-76-6C18H15ClN2O
2-(2-Methylphenyl)-N-(5-quinolinyl)acetamide chemical structure, C18H16N2O, CAS 1014497-97-2
2-(2-Methylphenyl)-N-(5-quinolinyl)acetamide
CAS 1014497-97-2C18H16N2O
N-(8-Butoxyquinolin-5-yl)-2-(4-methoxyphenyl)acetamide chemical structure, C22H24N2O3, CAS 942876-48-4
N-(8-Butoxyquinolin-5-yl)-2-(4-methoxyphenyl)acetamide
CAS 942876-48-4C22H24N2O3
N-(2-Methylquinolin-5-yl)-2-phenylbutanamide chemical structure, C20H20N2O, CAS 1207051-77-1
N-(2-Methylquinolin-5-yl)-2-phenylbutanamide
CAS 1207051-77-1C20H20N2O
N-(2,6-Dimethylquinolin-5-yl)-2-phenylacetamide chemical structure, C19H18N2O, CAS 1315351-13-3
N-(2,6-Dimethylquinolin-5-yl)-2-phenylacetamide
CAS 1315351-13-3C19H18N2O
5-(2-Amino-2-phenylacetamido)quinoline-8-carboxamide chemical structure, C18H16N4O2, CAS 1445782-10-4
5-(2-Amino-2-phenylacetamido)quinoline-8-carboxamide
CAS 1445782-10-4C18H16N4O2