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Murcko scaffold

Ring system with 4 rings and 22 atoms

840 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
840
With full pages
15
Scaffold SMILES

O=C(NC1CCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 840 chemicals

3-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)-4-methylpentanoic acid chemical structure, C27H32N2O5, CAS 2171356-00-4
3-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)-4-methylpentanoic acid
CAS 2171356-00-4C27H32N2O5
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}acetic acid chemical structure, C22H22N2O5, CAS 2171210-72-1
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}acetic acid
CAS 2171210-72-1C22H22N2O5
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3,3-dimethylbutanoic acid chemical structure, C26H30N2O5, CAS 2171714-20-6
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3,3-dimethylbutanoic acid
CAS 2171714-20-6C26H30N2O5
2-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)-2-methylbutanoic acid chemical structure, C26H30N2O5, CAS 2171424-22-7
2-({[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)-2-methylbutanoic acid
CAS 2171424-22-7C26H30N2O5
3-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-2-hydroxy-2-methylpropanoic acid chemical structure, C24H26N2O6, CAS 2171359-93-4
3-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-2-hydroxy-2-methylpropanoic acid
CAS 2171359-93-4C24H26N2O6
(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-4-hydroxybutanoic acid chemical structure, C24H26N2O6, CAS 2171165-13-0
(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-4-hydroxybutanoic acid
CAS 2171165-13-0C24H26N2O6
2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-5-methylhexanoic acid chemical structure, C27H32N2O5, CAS 2171660-93-6
2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-5-methylhexanoic acid
CAS 2171660-93-6C27H32N2O5
4-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}but-2-ynoic acid chemical structure, C24H22N2O5, CAS 2171803-49-7
4-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}but-2-ynoic acid
CAS 2171803-49-7C24H22N2O5
2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}acetic acid chemical structure, C24H26N2O5, CAS 2172220-08-3
2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}acetic acid
CAS 2172220-08-3C24H26N2O5
4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}butanoic acid chemical structure, C25H28N2O5, CAS 2171804-12-7
4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}butanoic acid
CAS 2171804-12-7C25H28N2O5
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-methylpropanoic acid chemical structure, C25H28N2O5, CAS 2172294-65-2
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-methylpropanoic acid
CAS 2172294-65-2C25H28N2O5
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid chemical structure, C27H32N2O5, CAS 2172320-75-9
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid
CAS 2172320-75-9C27H32N2O5
2-(2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}acetamido)acetic acid chemical structure, C24H25N3O6, CAS 2171169-23-4
2-(2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}acetamido)acetic acid
CAS 2171169-23-4C24H25N3O6
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3-hydroxy-3-methylbutanoic acid chemical structure, C25H28N2O6, CAS 2171322-51-1
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3-hydroxy-3-methylbutanoic acid
CAS 2171322-51-1C25H28N2O6
2-{1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylformamido}acetic acid chemical structure, C23H24N2O5, CAS 2171179-57-8
2-{1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylformamido}acetic acid
CAS 2171179-57-8C23H24N2O5
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid chemical structure, C24H26N2O5, CAS 2171180-49-5
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid
CAS 2171180-49-5C24H26N2O5
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid chemical structure, C25H28N2O5, CAS 2171301-23-6
4-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid
CAS 2171301-23-6C25H28N2O5
(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid chemical structure, C25H28N2O5, CAS 2171211-93-9
(2S)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid
CAS 2171211-93-9C25H28N2O5
3-{1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylformamido}propanoic acid chemical structure, C24H26N2O5, CAS 2171161-72-9
3-{1-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylformamido}propanoic acid
CAS 2171161-72-9C24H26N2O5
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-hydroxypropanoic acid chemical structure, C24H26N2O6, CAS 2171183-06-3
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-hydroxypropanoic acid
CAS 2171183-06-3C24H26N2O6
7-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}heptanoic acid chemical structure, C27H32N2O5, CAS 2171194-19-5
7-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}heptanoic acid
CAS 2171194-19-5C27H32N2O5
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-2-(methoxymethyl)butanoic acid chemical structure, C26H30N2O6, CAS 2171352-62-6
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-2-(methoxymethyl)butanoic acid
CAS 2171352-62-6C26H30N2O6
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3-hydroxy-2-methylpropanoic acid chemical structure, C24H26N2O6, CAS 2171331-84-1
2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3-hydroxy-2-methylpropanoic acid
CAS 2171331-84-1C24H26N2O6
(2R)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-4-methylpentanoic acid chemical structure, C26H30N2O5, CAS 2171244-61-2
(2R)-2-{[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-4-methylpentanoic acid
CAS 2171244-61-2C26H30N2O5