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Murcko scaffold

Ring system with 3 rings and 22 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
7
With full pages
3
Scaffold SMILES

O=S(=O)(NC1CCCCC1)c1ccc(-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NC1CCCCC1)c1ccc(-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-(2-Cyanoethyl)-N-cyclohexyl-4-(4-nitrophenyl)benzenesulfonamide chemical structure, C21H23N3O4S, CAS 301354-93-8
N-(2-Cyanoethyl)-N-cyclohexyl-4-(4-nitrophenyl)benzenesulfonamide
CAS 301354-93-8C21H23N3O4S
1-(4'-Methyl-[1,1'-biphenyl]-4-ylsulfonamido)cyclohexanecarboxylic acid chemical structure, C20H23NO4S, CAS 885269-28-3
1-(4'-Methyl-[1,1'-biphenyl]-4-ylsulfonamido)cyclohexanecarboxylic acid
CAS 885269-28-3C20H23NO4S
1-((4'-Chloro-[1,1'-biphenyl])-4-sulfonamido)cyclohexane-1-carboxylic acid chemical structure, C19H20ClNO4S, CAS 885269-38-5
1-((4'-Chloro-[1,1'-biphenyl])-4-sulfonamido)cyclohexane-1-carboxylic acid
CAS 885269-38-5C19H20ClNO4S
1-(4'-Methoxy-4-biphenylylsulfonylamino)cyclohexanecarboxylic acid chemical structure, C20H23NO5S, CAS 885269-48-7
1-(4'-Methoxy-4-biphenylylsulfonylamino)cyclohexanecarboxylic acid
CAS 885269-48-7C20H23NO5S
2',4'-Difluoro-N-(trans-4-hydroxycyclohexyl)biphenyl-4-sulfonamide chemical structure, C18H19F2NO3S, CAS 1218793-54-4
2',4'-Difluoro-N-(trans-4-hydroxycyclohexyl)biphenyl-4-sulfonamide
CAS 1218793-54-4C18H19F2NO3S
Methyl 4-(2',4'-difluorobiphenyl-4-ylsulfonamido)trans-cyclohexanecarboxylate chemical structure, C20H21F2NO4S, CAS 1218794-32-1
Methyl 4-(2',4'-difluorobiphenyl-4-ylsulfonamido)trans-cyclohexanecarboxylate
CAS 1218794-32-1C20H21F2NO4S
[1,1'-Biphenyl]-4-sulfonamide, 4'-chloro-2'-cyano-N-(trans-4-hydroxy-4-methylcyclohexyl)- chemical structure, C20H21ClN2O3S, CAS 1642602-54-7
[1,1'-Biphenyl]-4-sulfonamide, 4'-chloro-2'-cyano-N-(trans-4-hydroxy-4-methylcyclohexyl)-
CAS 1642602-54-7C20H21ClN2O3S