CompoundList
Sign in
Murcko scaffold

N5-phenyl-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine scaffold

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
4
With full pages
3
Scaffold SMILES

N=c1c2cn[nH]c2ncn1Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N5-phenyl-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine page
Murcko scaffold N=c1c2cn[nH]c2ncn1Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

N5-phenyl-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine chemical structure, C11H10N6, CAS 477872-95-0
N5-phenyl-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine
CAS 477872-95-0C11H10N6
N5-(4-chlorophenyl)-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine chemical structure, C11H9ClN6, CAS 338403-44-4
N5-(4-chlorophenyl)-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine
CAS 338403-44-4C11H9ClN6
N5-(2,4-dichlorophenyl)pyrazolo[3,4-d]pyrimidine-4,5-diamine chemical structure, C11H8Cl2N6, CAS 338403-46-6
N5-(2,4-dichlorophenyl)pyrazolo[3,4-d]pyrimidine-4,5-diamine
CAS 338403-46-6C11H8Cl2N6
N5-(2-fluorophenyl)-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine chemical structure, C11H9FN6, CAS 338403-49-9
N5-(2-fluorophenyl)-5H-pyrazolo[3,4-d]pyrimidine-4,5-diamine
CAS 338403-49-9C11H9FN6