Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 23 atoms

25 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 23
Chemicals: 25
With full pages: 4

Scaffold SMILES

O=C(CN1C(=O)NC(c2ccccc2)C1=O)NC1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CN1C(=O)NC(c2ccccc2)C1=O)NC1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

N-(2,3-Dimethylcyclohexyl)-2-[4-ethyl-4-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C21H28FN3O3, CAS 1005272-97-8

N-(2,3-Dimethylcyclohexyl)-2-[4-ethyl-4-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 1005272-97-8C₂₁H₂₈FN₃O₃

2-[4-(4-Chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(2-methylcyclohexyl)acetamide chemical structure, C19H24ClN3O3, CAS 1177741-98-8

2-[4-(4-Chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(2-methylcyclohexyl)acetamide

CAS 1177741-98-8C₁₉H₂₄ClN₃O₃

N-(1-Cyanocyclohexyl)-2-[4-methyl-4-(4-nitrophenyl)-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C19H21N5O5, CAS 956767-35-4

N-(1-Cyanocyclohexyl)-2-[4-methyl-4-(4-nitrophenyl)-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 956767-35-4C₁₉H₂₁N₅O₅

2-(4-(4-Chlorophenyl)-4-ethyl-2,5-dioxoimidazolidin-1-yl)-N-(1-cyanocyclohexyl)acetamide chemical structure, C20H23ClN4O3, CAS 878213-16-2

2-(4-(4-Chlorophenyl)-4-ethyl-2,5-dioxoimidazolidin-1-yl)-N-(1-cyanocyclohexyl)acetamide

CAS 878213-16-2C₂₀H₂₃ClN₄O₃

N-(1-Cyanocyclohexyl)-2-(4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl)acetamide chemical structure, C20H24N4O4, CAS 956366-24-8

N-(1-Cyanocyclohexyl)-2-(4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl)acetamide

CAS 956366-24-8C₂₀H₂₄N₄O₄

2-[4-(4-Chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1-cyanocyclohexyl)acetamide chemical structure, C19H21ClN4O3, CAS 956738-54-8

2-[4-(4-Chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1-cyanocyclohexyl)acetamide

CAS 956738-54-8C₁₉H₂₁ClN₄O₃

N-(1-Cyanocyclohexyl)-2-[4-ethyl-4-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C20H23FN4O3, CAS 926612-98-8

N-(1-Cyanocyclohexyl)-2-[4-ethyl-4-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 926612-98-8C₂₀H₂₃FN₄O₃

N-(1-Cyanocyclohexyl)-2-{4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl}acetamide chemical structure, C20H22F2N4O4, CAS 956738-55-9

N-(1-Cyanocyclohexyl)-2-{4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl}acetamide

CAS 956738-55-9C₂₀H₂₂F₂N₄O₄

N-Cyclohexyl-2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C19H25N3O4, CAS 1052561-75-7

N-Cyclohexyl-2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 1052561-75-7C₁₉H₂₅N₃O₄

3-(1-(2-(Cyclohexylamino)-2-oxoethyl)-2,5-dioxo-4-phenylimidazolidin-4-yl)propanoic acid chemical structure, C20H25N3O5, CAS 941905-28-8

3-(1-(2-(Cyclohexylamino)-2-oxoethyl)-2,5-dioxo-4-phenylimidazolidin-4-yl)propanoic acid

CAS 941905-28-8C₂₀H₂₅N₃O₅

N-(1-Cyanocyclohexyl)-2-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetamide chemical structure, C19H22N4O3, CAS 1052572-97-0

N-(1-Cyanocyclohexyl)-2-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetamide

CAS 1052572-97-0C₁₉H₂₂N₄O₃

2-[4-(3-Bromophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1-cyanocyclohexyl)-N-methylacetamide chemical structure, C20H23BrN4O3, CAS 1052580-46-7

2-[4-(3-Bromophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1-cyanocyclohexyl)-N-methylacetamide

CAS 1052580-46-7C₂₀H₂₃BrN₄O₃

N-(1-Cyanocyclohexyl)-2-[4-methyl-4-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C20H24N4O3, CAS 1008291-66-4

N-(1-Cyanocyclohexyl)-2-[4-methyl-4-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 1008291-66-4C₂₀H₂₄N₄O₃

N-(1-Cyanocyclohexyl)-2-[4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-methylacetamide chemical structure, C20H22Cl2N4O3, CAS 1052616-77-9

N-(1-Cyanocyclohexyl)-2-[4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-methylacetamide

CAS 1052616-77-9C₂₀H₂₂Cl₂N₄O₃

N-(1-Cyanocyclohexyl)-N-methyl-2-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetamide chemical structure, C20H24N4O3, CAS 1052579-52-8

N-(1-Cyanocyclohexyl)-N-methyl-2-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetamide

CAS 1052579-52-8C₂₀H₂₄N₄O₃

N-(1-Cyanocyclohexyl)-2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetamide chemical structure, C20H24N4O3, CAS 1008021-88-2

N-(1-Cyanocyclohexyl)-2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetamide

CAS 1008021-88-2C₂₀H₂₄N₄O₃

N-(1-Cyanocyclohexyl)-2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-methylacetamide chemical structure, C20H23FN4O3, CAS 1134676-50-8

N-(1-Cyanocyclohexyl)-2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-methylacetamide

CAS 1134676-50-8C₂₀H₂₃FN₄O₃

2-[4-(2-Chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1-cyanocyclohexyl)acetamide chemical structure, C19H21ClN4O3, CAS 1008446-55-6

2-[4-(2-Chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1-cyanocyclohexyl)acetamide

CAS 1008446-55-6C₁₉H₂₁ClN₄O₃

N-(1-Cyanocyclohexyl)-2-{4-methyl-2,5-dioxo-4-[2-(trifluoromethyl)phenyl]imidazolidin-1-yl}acetamide chemical structure, C20H21F3N4O3, CAS 1223373-78-1

N-(1-Cyanocyclohexyl)-2-{4-methyl-2,5-dioxo-4-[2-(trifluoromethyl)phenyl]imidazolidin-1-yl}acetamide

CAS 1223373-78-1C₂₀H₂₁F₃N₄O₃

N-(1-Cyanocyclohexyl)-2-[4-methyl-2,5-dioxo-4-[3-(trifluoromethyl)phenyl]imidazolidin-1-yl]acetamide chemical structure, C20H21F3N4O3, CAS 1223483-91-7

N-(1-Cyanocyclohexyl)-2-[4-methyl-2,5-dioxo-4-[3-(trifluoromethyl)phenyl]imidazolidin-1-yl]acetamide

CAS 1223483-91-7C₂₀H₂₁F₃N₄O₃

N-(1-Cyanocyclohexyl)-2-[4-(2-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C19H21FN4O3, CAS 1252316-92-9

N-(1-Cyanocyclohexyl)-2-[4-(2-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 1252316-92-9C₁₉H₂₁FN₄O₃

N-(1-Cyanocyclohexyl)-2-[4-(3-cyanophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C20H21N5O3, CAS 1252485-20-3

N-(1-Cyanocyclohexyl)-2-[4-(3-cyanophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 1252485-20-3C₂₀H₂₁N₅O₃

N-(1-Cyanocyclohexyl)-N-methyl-2-[4-methyl-4-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl]acetamide chemical structure, C21H26N4O3, CAS 1287132-26-6

N-(1-Cyanocyclohexyl)-N-methyl-2-[4-methyl-4-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl]acetamide

CAS 1287132-26-6C₂₁H₂₆N₄O₃

N-(1-Cyanocyclohexyl)-2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)-N-methylacetamide chemical structure, C21H26N4O3, CAS 1240641-27-3

N-(1-Cyanocyclohexyl)-2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)-N-methylacetamide

CAS 1240641-27-3C₂₁H₂₆N₄O₃

N-(1-Cyanocyclohexyl)-2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-methylacetamide
1276436-79-3C₂₁H₂₆N₄O₄